CIRONE, Mara
 Distribuzione geografica
Continente #
NA - Nord America 5.228
EU - Europa 1.821
AS - Asia 1.013
AF - Africa 53
SA - Sud America 24
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.143
Nazione #
US - Stati Uniti d'America 5.199
IT - Italia 952
SG - Singapore 456
IN - India 233
CN - Cina 209
SE - Svezia 153
IE - Irlanda 144
FI - Finlandia 143
DE - Germania 99
UA - Ucraina 87
ID - Indonesia 61
GB - Regno Unito 51
BG - Bulgaria 31
RU - Federazione Russa 31
TG - Togo 26
AT - Austria 25
CA - Canada 23
NL - Olanda 22
RO - Romania 19
EG - Egitto 18
JP - Giappone 18
FR - Francia 16
HK - Hong Kong 14
AR - Argentina 13
ES - Italia 11
BE - Belgio 9
KR - Corea 8
CL - Cile 7
GR - Grecia 7
CH - Svizzera 5
ZA - Sudafrica 5
MX - Messico 4
AU - Australia 3
BR - Brasile 3
CY - Cipro 3
TR - Turchia 3
CD - Congo 2
HR - Croazia 2
IR - Iran 2
LT - Lituania 2
LV - Lettonia 2
MY - Malesia 2
PL - Polonia 2
AL - Albania 1
AM - Armenia 1
BY - Bielorussia 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
EU - Europa 1
IS - Islanda 1
JM - Giamaica 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
MA - Marocco 1
MD - Moldavia 1
NO - Norvegia 1
PA - Panama 1
PT - Portogallo 1
SC - Seychelles 1
UY - Uruguay 1
UZ - Uzbekistan 1
Totale 8.143
Città #
Fairfield 865
Rome 449
Ashburn 387
Chandler 376
Woodbridge 376
Houston 340
Singapore 333
Seattle 313
Cambridge 270
Wilmington 269
Dearborn 176
Ann Arbor 158
Dublin 143
Princeton 127
New York 125
Santa Clara 121
San Paolo di Civitate 114
Lawrence 97
Helsinki 77
Plano 72
Beijing 66
Boston 66
Jakarta 61
San Diego 59
Millbury 49
Bremen 40
Andover 36
Milan 36
Latina 31
Jacksonville 28
Sofia 28
Shanghai 27
Lomé 26
Des Moines 23
Norwalk 22
Vienna 20
Toronto 19
Boardman 18
Phoenix 16
Cairo 15
Fremont 15
Okinawa 15
Menlo Park 14
Federal 12
Nuremberg 12
Hefei 11
Los Angeles 11
Barcelona 10
Mannheim 10
Moscow 10
Genoa 9
Hong Kong 9
Lappeenranta 9
Nanjing 9
Washington 9
Brussels 8
London 8
Nanchang 8
Falls Church 7
San Mateo 7
Bühl 6
Frankfurt am Main 6
Grafing 6
Kunming 6
Athens 5
Cerveteri 5
Chicago 5
Falkenstein 5
Guangzhou 5
Pune 5
Santiago 5
Amsterdam 4
Auburn Hills 4
Bern 4
Dallas 4
Jinan 4
Putignano 4
Rimini 4
Sacramento 4
Shenyang 4
Southend 4
Trieste 4
Ahmedabad 3
Al Maḩallah al Kubrá 3
Altavilla Vicentina 3
Atlanta 3
Bologna 3
Brescia 3
Chengdu 3
Clifton 3
Edinburgh 3
Fuzhou 3
Gainesville 3
Istanbul 3
Limassol 3
Muizenberg 3
Padova 3
Pomezia 3
Shenzhen 3
Solna 3
Totale 6.234
Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 186
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 129
Infection by Human Herpesvirus 6 (HHV-6) of human lymphoid T cells occurs through an endocytic pathway. 120
EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation 118
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells 118
Superinfection by Epstein-Barr virus of a subset of Raji cells is independent of HLA class II antigens 114
KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression 106
Human herpesvirus 6 variant A, but not variant B, infects EBV-positive B lymphoid cells, activating the latent EBV genome through a BZLF-1-dependent mechanism 106
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma 105
HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2 105
The activation of KSHV lytic cycle blocks autophagy in PEL cells 104
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways 102
Early interactions of human herpesvirus 6 with lymphoid cells: Role of membrane protein components and glycosaminoglycans in virus binding 102
Differential regulation of miR-21 and miR-146a by Epstein-Barr virus-encoded EBNA2 100
EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3 100
Epstein-Barr virus infection leads to partial phenotypic reversion of terminally differentiated malignant B cells. 100
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death 99
Activation of dendritic cells by tumor cell death 97
Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future 95
Cytotoxic drugs activate KSHV lytic cycle in latently infected PEL cells by inducing a moderate ROS increase controlled by HSF1, NRF2 and p62/SQSTM1 95
Capsaicin-mediated apoptosis of human bladder cancer cells activates dendritic cells via Cd91 94
Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma 94
Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death 90
Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells 89
Events related to Epstein-Barr virus binding and superinfection of Raji cells 87
Capping of Hla Antigens In Human-lymphocytes As Followed By Immunogold Label-fracture 86
Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy 86
Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences 86
Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression 86
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells 85
DENDRITIC CELL DIFFERENTIATION BLOCKED BY PRIMARY EFFUSION LYMPHOMA-RELEASED FACTORS IS PARTIALLY RESTORED BY INHIBITION OF P38 MAPK 85
Stat3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation 85
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma 84
Human herpesvirus 8 (HHV-8) inhibits monocyte differentiation into dendritic cells and impairs their immunostimulatory activity 83
Human herpesvirus 6 and multiple sclerosis: A study of T cell cross-reactivity to viral and myelin basic protein antigens 82
Epigenetic mechanisms do not control viral latency III in primary effusion lymphoma cells infected with a recombinant Epstein-Barr virus. 82
Degradation of mutant p53H175 protein by Zn(II) through autophagy 81
Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin 81
Epstein-Barr Virus Blocks the Autophagic Flux and Appropriates the Autophagic Machinery To Enhance Viral Replication 80
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation 80
Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice 80
Reactivation of mutant p53 by capsaicin, the major constituent of peppers 79
Hyperglycemia triggers HIPK2 protein degradation 77
Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response 77
Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress 77
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy 76
HHV-6 infection in Italy: characterization of an endemic isolate and seroepidemiologic analysis. 76
Cyclooxygenase-2 is induced by p38 MAPK and promotes cell survival 74
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease 74
BFRF1 protein is involved in EBV-mediated autophagy manipulation 74
HHV-8 reduces dendritic cell migration through down-regulation of cell-surface CCR6 and CCR7 and cytoskeleton reorganization 74
Intracellular transport and maturation pathway of human herpesvirus 6 73
Elevated antinuclear antibodies and altered anti-Epstein-Barr virus immune responses. 73
Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses 73
P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions 72
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status 70
Epstein-Barr virus internalization and infectivity are blocked by selective protein kinase C inhibitors 69
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK 69
KSHV ORF67 encoded lytic protein localizes on the nuclear membrane and alters emerin distribution 68
Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line. 68
JNK and Macroautophagy Activation by Bortezomib Has a Pro-Survival Effect in Primary Effusion Lymphoma Cells 68
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression 68
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells 68
Targeting COX-2/PGE2 Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation 67
Consensus guidelines for the detection of immunogenic cell death 67
Epstein-Barr Virus Infection Induces Aberrant TLR Activation Pathway and Fibroblast-Myofibroblast Conversion in Scleroderma. 67
HHV-6B reduces autophagy and induces ER stress in primary monocytes impairing their survival and differentiation into dendritic cells 67
PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function 67
Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization 66
Antiviral filtering capacity of go-coated textiles 66
Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cells 64
Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy 63
Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease? 62
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor 62
Primary Effusion Lymphoma Cell Death Induced by Bortezomib and AG 490 Activates Dendritic Cells through CD91 60
Mutant p53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and p62 that induces chemio-resistance to Apigenin in pancreatic cancer cells 60
PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction 60
Epstein-Barr virus DNA is present both in CD10/CD77 positive and negative subsets of human tonsillar lymphocytes. 59
KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral-driven sarcomagenesis 58
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication 57
EBV and KSHV Infection Dysregulates Autophagy to Optimize Viral Replication, Prevent Immune Recognition and Promote Tumorigenesis 56
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation 56
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway 56
p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53 54
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR 52
Viral Infection and Autophagy Dysregulation. The Case of HHV-6, EBV and KSHV 52
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation 51
The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B 51
Localization of Epstein-Barr virus envelope glycoproteins over the nuclear membrane of virus producing cells 50
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 50
Mutant p53 and cellular stress pathways: a criminal alliance that promotes cancer progression 49
Viral glycoproteins accumulate in newly formed annulate lamellae following infection of lymphoid cells by human herpesvirus 6 49
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells 49
Ire1 alpha/xbp1 axis sustains primary effusion lymphoma cell survival by promoting cytokine release and stat3 activation 49
Hepatitis C virus present in the sera of infected patients interferes with the autophagic process of monocytes impairing their in-vitro differentiation into dendritic cells 49
STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells 47
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells 47
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells 47
Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells 45
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment 43
Totale 7.658
Categoria #
all - tutte 28.692
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.692


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020925 0 0 0 0 0 0 268 186 207 135 60 69
2020/2021936 80 77 45 33 20 26 23 58 108 196 77 193
2021/20221.477 27 56 135 72 160 40 26 142 81 100 382 256
2022/20231.493 240 326 46 157 252 132 16 83 115 29 70 27
2023/20241.079 65 95 54 82 111 192 38 118 19 103 90 112
2024/2025897 53 161 129 157 185 210 2 0 0 0 0 0
Totale 8.645