BRUNO, Valeria Maria Gloria
 Distribuzione geografica
Continente #
NA - Nord America 8.340
EU - Europa 1.856
AS - Asia 1.197
SA - Sud America 50
AF - Africa 42
OC - Oceania 1
Totale 11.486
Nazione #
US - Stati Uniti d'America 8.280
IT - Italia 654
IN - India 518
CN - Cina 470
FI - Finlandia 320
UA - Ucraina 299
SE - Svezia 229
SG - Singapore 162
DE - Germania 94
GB - Regno Unito 69
IE - Irlanda 62
CA - Canada 51
AR - Argentina 41
BG - Bulgaria 41
TG - Togo 38
BE - Belgio 16
IR - Iran 16
RO - Romania 13
AT - Austria 11
NL - Olanda 10
FR - Francia 9
MX - Messico 9
TR - Turchia 8
CH - Svizzera 7
RU - Federazione Russa 6
VN - Vietnam 6
CL - Cile 5
PL - Polonia 4
BR - Brasile 3
ES - Italia 3
GR - Grecia 3
JP - Giappone 3
SC - Seychelles 3
DK - Danimarca 2
KR - Corea 2
LK - Sri Lanka 2
MY - Malesia 2
AE - Emirati Arabi Uniti 1
BD - Bangladesh 1
CZ - Repubblica Ceca 1
HR - Croazia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
NZ - Nuova Zelanda 1
PY - Paraguay 1
TH - Thailandia 1
TJ - Tagikistan 1
ZA - Sudafrica 1
Totale 11.486
Città #
Fairfield 1.339
Ashburn 818
Chandler 709
Woodbridge 675
Houston 472
Wilmington 462
Beijing 427
Cambridge 426
Seattle 420
Ann Arbor 327
Princeton 286
Plano 272
San Paolo di Civitate 235
Rome 191
Lawrence 151
Boston 134
Jacksonville 130
Millbury 116
San Diego 90
Andover 78
Singapore 74
Norwalk 70
Des Moines 66
Dublin 61
Helsinki 56
Boardman 49
Fremont 45
Bremen 44
Toronto 43
Sofia 41
Federal 40
Lomé 38
Falls Church 33
San Mateo 28
New York 26
Bühl 17
Dearborn 17
Brussels 16
Milan 14
Southend 11
Buffalo 9
Lecce 9
Caldogno 8
Istanbul 8
Los Angeles 8
Vienna 8
Auburn Hills 7
Bern 7
Indiana 7
Nanjing 7
Ottawa 7
Ailano 6
Hefei 6
Latina 6
Laurel 6
Turin 6
Florence 5
Kunming 5
Mannheim 5
Naples 5
Phoenix 5
Trumbull 5
Dallas 4
London 4
Mexico City 4
Newark 4
Trezzano sul Naviglio 4
Calvizzano 3
Castellammare Di Stabia 3
Grafing 3
Guangzhou 3
Kashan 3
Lublin 3
L’Aquila 3
Nanchang 3
Napoli 3
Prescot 3
Provo 3
Sant'Elena Sannita 3
Agrigento 2
Arezzo 2
Barcelona 2
Bari 2
Capri 2
Casalbordino 2
Caserta 2
Catania 2
Charleston 2
Chiswick 2
Colleferro 2
Colombo 2
Frascati 2
Genova 2
Guastameroli 2
Gunzenhausen 2
Hangzhou 2
Ho Chi Minh City 2
Hounslow 2
Innsbruck 2
Kilburn 2
Totale 8.790
Nome #
Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice 120
Xanthurenic Acid Activates mGlu2/3 metabotropic glutamate receptors and is a potential trait marker for schizophrenia 105
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain 102
Alterations in the α2δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies 102
Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome. 96
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells 93
Activation of excitatory amino acid receptors reduces thymidine incorporation and cell proliferation rate in primary cultures of astrocytes. 87
Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic cerebellar samples from patients with multiple sclerosis 82
D-Aspartate activates mGlu receptors coupled to polyphosphoinositide hydrolysis in neonate rat brain slices 81
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors 79
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors 79
Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors. 78
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways 78
Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration 77
Antidepressant activity of fingolimod in mice 76
Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons 76
Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications 76
Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons 76
Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy 75
Tic disorders: from pathophysiology to treatment 75
Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism. 75
Dickkopf-3 upregulates VEGF in cultured human endothelial cells by activating activin receptor-like Kinase 1 (ALK1) Pathway 74
Metabotropic glutamate receptors: Beyond the regulation of synaptic transmission 74
Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy") 74
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. 74
ACTIVATION OF CELL-CYCLE-ASSOCIATED PROTEINS IN NEURONAL DEATH: A MANDATORY OR DISPENSABLE PATH? 73
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. 73
The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons 73
Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures 73
GABAergic drugs become neurotoxic in cortical neurons pre-exposed to brain-derived neurotrophic factor. 73
THE MAMMALIAN HOMOLOGUE OF THE NOVEL PEPTIDE Bv8 IS EXPRESSED IN THE CENTRAL NERVOUS SYSTEM AND SUPPORTS NEURONAL SURVIVAL BY ACTIVATING THE MAP KINASE/PI-3-KINASE PATHWAYS 72
Comparative effects of levobupivacaine and racemic bupivacaine on excitotoxic neuronal death in culture and N-methyl-D-aspartate-induced seizures in mice 72
TGF-β1 pathway as a new target for neuroprotection in alzheimer's disease 72
Selective activation of group II metabotropic glutamate receptors is protective against excitotoxic neuronal death 72
Vasorelaxing action of the kynurenine metabolite, xanthurenic acid: the missing link in endotoxin-induced hypotension? 72
Early defect of transforming growth factor β1 formation in Huntington's disease. 72
Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons 71
A NOVEL RAT GENE ENCODING A HUMANIN-LIKE PEPTIDE ENDOWED WITH BROAD NEUROPROTECTIVE ACTIVITY 71
Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia 71
ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS PREVENTS NEURONAL APOPTOSIS IN CULTURE 70
Metabotropic Glutamate Receptors in Glial Cells 70
Expression of the K(+)/Cl(-) cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors 68
The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia 68
Testosterone amplifies excitotoxic damage of cultured oligodendrocytes. 67
Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors 67
Activation of excitatory amino acid receptors regulates growth and proliferation of glial cells in primary cultures 67
Neurotrasmissione mediata da aminoacidi eccitatori. 66
Inositol hexakisphosphate (phytic acid) enhances Ca2+ influx and D-[3H]aspartate release in cultured cerebellar neurons. 66
Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy. 66
Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO 65
Activation of group-III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures 65
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system 65
ACTIVATION OF A(1) ADENOSINE OR mGLU3 METABOTROPIC GLUTAMATE RECEPTORS ENHANCES THE RELEASE OF NERVE GROWTH FACTOR AND S-100BETA PROTEIN FROM CULTURED ASTROCYTES 64
Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures 64
Early defect of transforming growth factor b-1 formation in Huntington's disease 64
null 64
The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders 63
Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 62
Enhanced expression of Harvey ras induced by serum deprivation in cultured astrocytes 62
Mouse hepatocytes lacking mGlu5 metabotropic glutamate receptors are less sensitive to hypoxic damage 62
The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling 61
Protection against hypoxia-induced hepatocyte damage in mGluR5 knockout mice 60
Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status 60
Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures 60
The Wnt Antagonist, Dickkopf-1, as a Target for the Treatment of Neurodegenerative Disorders 60
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells 59
Fingolimod protects cultured cortical neurons against excitotoxic death 59
Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death 58
N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors 57
Receptors for inositolhexakisphosphate in neurons and anterior pituitary cells. 55
Metabotropic glutamate receptors and neuronal apoptosis in culture. 55
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders? 54
Thyrotropin releasing hormone (TRH) and its analog, RGH-2202, accelerate maturation of cerebellar neurons in vitro. 54
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids 54
null 54
Protective role for type 4 metabotropic glutamate receptors against ischemic brain damage 54
null 54
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice 54
Molecular signaling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes 53
Metabotropic glutamate receptors as drug target in brain ischemia. 53
null 53
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors 53
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death. 52
Protective action of idebenone against excitotoxic degeneration in cultured cortical neurons. 52
(-)-PHCCC, a positive allosteric modulator selective for metabotropic glutamate receptor subtype 4: pharmacological and molecular characterization. 52
Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo 51
The preferential. mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy 51
SYSTEMICALLY ADMINISTERED D-GLUCOSE CONJUGATES OF 7-CHLOROKYNURETIC ACID ARE CENTRALLY AVAILABLE AND EXERT ANTICONVULSANT ACTIVITY IN RODENTS 51
Indolpyruvic acid (IPA) acts as an antagonist of Mg2+-sensitive glutamate receptors in cerebellar neurons 51
Synthesis, pharmacokinetics and anticonvulsant activity of 7-chlorokynurenic acid prodrugs 51
Excitatory amino acids stimulate inositol phospholipid hydrolysis and reduce proliferation in cultured astrocytes. 50
Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes 50
Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus 50
Pharmacological activation of mGlu5 receptors with the positive allosteric modulator VU0360172, modulates thalamic GABAergic transmission 50
Induction of Dickkopf-1, a negative modulator of the wnt pathway, is required for the development of ischemic neuronal death 49
Neuroprotective activity of metabotropic glutamate receptor ligands 49
GLIA MODULATE THE RESPONSE OF MURINE CORTICAL-NEURONS TO EXCITOTOXICITY - GLIA EXACERBATE AMPA NEUROTOXICITY 49
GABAergic drugs become neurotoxic in cortical neurons pre-exposed to brain-derived neurotrophic factor. 49
Expression and function of metabotropic glutamate receptors in liver 49
Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Contributes to the Development of Nigro-Striatal Damage Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice 49
Totale 6.608
Categoria #
all - tutte 33.614
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.614


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019899 0 0 0 0 0 0 0 0 0 0 529 370
2019/20202.725 449 113 30 116 250 245 281 302 279 256 341 63
2020/2021861 99 97 53 101 27 68 11 122 99 92 69 23
2021/20222.504 27 184 259 44 357 44 50 274 198 211 311 545
2022/20232.481 561 571 63 256 288 246 13 139 185 25 89 45
2023/20241.096 99 142 44 75 115 296 9 75 7 154 80 0
Totale 11.792