BRUNO, Valeria Maria Gloria
 Distribuzione geografica
Continente #
NA - Nord America 8.736
EU - Europa 2.118
AS - Asia 1.810
SA - Sud America 54
AF - Africa 43
OC - Oceania 2
Totale 12.763
Nazione #
US - Stati Uniti d'America 8.663
IT - Italia 763
SG - Singapore 747
IN - India 518
CN - Cina 483
FI - Finlandia 342
UA - Ucraina 299
SE - Svezia 229
DE - Germania 138
GB - Regno Unito 77
IE - Irlanda 67
CA - Canada 63
RU - Federazione Russa 62
AR - Argentina 41
BG - Bulgaria 41
TG - Togo 39
BE - Belgio 20
IR - Iran 16
NL - Olanda 14
AT - Austria 13
RO - Romania 13
ID - Indonesia 11
FR - Francia 10
MX - Messico 9
TR - Turchia 8
CH - Svizzera 7
BR - Brasile 6
PL - Polonia 6
VN - Vietnam 6
CL - Cile 5
ES - Italia 4
KR - Corea 4
GR - Grecia 3
JP - Giappone 3
LK - Sri Lanka 3
LT - Lituania 3
SC - Seychelles 3
DK - Danimarca 2
MY - Malesia 2
AE - Emirati Arabi Uniti 1
AU - Australia 1
BD - Bangladesh 1
BO - Bolivia 1
BY - Bielorussia 1
CZ - Repubblica Ceca 1
GE - Georgia 1
HR - Croazia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PY - Paraguay 1
TH - Thailandia 1
TJ - Tagikistan 1
ZA - Sudafrica 1
Totale 12.763
Città #
Fairfield 1.339
Ashburn 820
Chandler 709
Woodbridge 675
Singapore 550
Houston 472
Wilmington 462
Beijing 427
Cambridge 426
Seattle 421
Ann Arbor 327
Princeton 286
Plano 272
San Paolo di Civitate 235
Rome 217
Santa Clara 152
Lawrence 151
Boston 134
Jacksonville 130
Millbury 116
Boardman 98
San Diego 90
Andover 78
Helsinki 78
Norwalk 70
Des Moines 66
Dublin 66
Toronto 48
Fremont 45
Bremen 44
Moscow 43
Sofia 41
Federal 40
Lomé 39
Falls Church 33
Falkenstein 28
San Mateo 28
New York 26
Brussels 20
Bühl 17
Dearborn 17
Milan 15
Mannheim 13
Ottawa 13
Dallas 12
Jakarta 11
Seregno 11
Southend 11
Naples 10
Vienna 10
Buffalo 9
Lecce 9
London 9
Los Angeles 9
Caldogno 8
Istanbul 8
Latina 8
Auburn Hills 7
Bern 7
Florence 7
Indiana 7
Nanjing 7
Ailano 6
Empoli 6
Hefei 6
Laurel 6
Turin 6
Bologna 5
Frankfurt am Main 5
Kunming 5
Phoenix 5
Trumbull 5
Bari 4
Mexico City 4
Newark 4
Trezzano sul Naviglio 4
Aversa 3
Calvizzano 3
Castellammare Di Stabia 3
Colleferro 3
Colombo 3
Fisciano 3
Grafing 3
Guangzhou 3
Kashan 3
Lublin 3
L’Aquila 3
Nanchang 3
Napoli 3
Prescot 3
Provo 3
Sant'Elena Sannita 3
Urbino 3
Agrigento 2
Amsterdam 2
Arezzo 2
Barcelona 2
Capri 2
Casalbordino 2
Caserta 2
Totale 9.673
Nome #
Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice 124
Xanthurenic Acid Activates mGlu2/3 metabotropic glutamate receptors and is a potential trait marker for schizophrenia 122
Alterations in the α2δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies 115
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain 111
Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome. 104
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells 98
D-Aspartate activates mGlu receptors coupled to polyphosphoinositide hydrolysis in neonate rat brain slices 91
Antidepressant activity of fingolimod in mice 91
Activation of excitatory amino acid receptors reduces thymidine incorporation and cell proliferation rate in primary cultures of astrocytes. 90
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors 90
Dickkopf-3 upregulates VEGF in cultured human endothelial cells by activating activin receptor-like Kinase 1 (ALK1) Pathway 86
Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic cerebellar samples from patients with multiple sclerosis 86
Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration 86
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors 82
Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism. 82
Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons 82
The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia 82
Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors. 81
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. 81
Metabotropic glutamate receptors: Beyond the regulation of synaptic transmission 81
Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy") 80
Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons 79
Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications 79
Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy 78
Tic disorders: from pathophysiology to treatment 78
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways 78
Early defect of transforming growth factor β1 formation in Huntington's disease. 78
Comparative effects of levobupivacaine and racemic bupivacaine on excitotoxic neuronal death in culture and N-methyl-D-aspartate-induced seizures in mice 77
Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures 77
Vasorelaxing action of the kynurenine metabolite, xanthurenic acid: the missing link in endotoxin-induced hypotension? 77
Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons 77
ACTIVATION OF CELL-CYCLE-ASSOCIATED PROTEINS IN NEURONAL DEATH: A MANDATORY OR DISPENSABLE PATH? 76
A NOVEL RAT GENE ENCODING A HUMANIN-LIKE PEPTIDE ENDOWED WITH BROAD NEUROPROTECTIVE ACTIVITY 76
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. 76
GABAergic drugs become neurotoxic in cortical neurons pre-exposed to brain-derived neurotrophic factor. 76
ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS PREVENTS NEURONAL APOPTOSIS IN CULTURE 75
The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons 74
Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia 74
TGF-β1 pathway as a new target for neuroprotection in alzheimer's disease 74
Selective activation of group II metabotropic glutamate receptors is protective against excitotoxic neuronal death 74
THE MAMMALIAN HOMOLOGUE OF THE NOVEL PEPTIDE Bv8 IS EXPRESSED IN THE CENTRAL NERVOUS SYSTEM AND SUPPORTS NEURONAL SURVIVAL BY ACTIVATING THE MAP KINASE/PI-3-KINASE PATHWAYS 73
Metabotropic Glutamate Receptors in Glial Cells 73
Enhanced expression of Harvey ras induced by serum deprivation in cultured astrocytes 71
Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors 71
Activation of group-III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures 71
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system 71
Testosterone amplifies excitotoxic damage of cultured oligodendrocytes. 70
Expression of the K(+)/Cl(-) cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors 70
Early defect of transforming growth factor b-1 formation in Huntington's disease 69
Activation of excitatory amino acid receptors regulates growth and proliferation of glial cells in primary cultures 69
Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy. 69
ACTIVATION OF A(1) ADENOSINE OR mGLU3 METABOTROPIC GLUTAMATE RECEPTORS ENHANCES THE RELEASE OF NERVE GROWTH FACTOR AND S-100BETA PROTEIN FROM CULTURED ASTROCYTES 68
Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status 68
Neurotrasmissione mediata da aminoacidi eccitatori. 67
Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO 67
Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures 66
Inositol hexakisphosphate (phytic acid) enhances Ca2+ influx and D-[3H]aspartate release in cultured cerebellar neurons. 66
Protection against hypoxia-induced hepatocyte damage in mGluR5 knockout mice 65
The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders 65
Mouse hepatocytes lacking mGlu5 metabotropic glutamate receptors are less sensitive to hypoxic damage 65
The Wnt Antagonist, Dickkopf-1, as a Target for the Treatment of Neurodegenerative Disorders 65
Fingolimod protects cultured cortical neurons against excitotoxic death 65
Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 64
null 64
(-)-PHCCC, a positive allosteric modulator selective for metabotropic glutamate receptor subtype 4: pharmacological and molecular characterization. 64
Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures 64
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells 64
The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling 63
N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors 61
Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death 61
A Progressive build-up of perineuronal nets in the Somatosensory Cortex Is Associated with the Development of Chronic Pain in Mice 61
Pharmacological activation of mGlu5 receptors with the positive allosteric modulator VU0360172, modulates thalamic GABAergic transmission 60
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice 60
Molecular signaling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes 59
Metabotropic glutamate receptors as drug target in brain ischemia. 57
Metabotropic glutamate receptors and neuronal apoptosis in culture. 57
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders? 56
Receptors for inositolhexakisphosphate in neurons and anterior pituitary cells. 56
Protective role for type 4 metabotropic glutamate receptors against ischemic brain damage 56
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors 56
Growth conditions differentially affect the constitutive expression of primary response genes in cultured cerebellar granule cells 56
Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage 55
(2S,1’R,2’R,3’R)-2-(2,3-Dicarboxycyclopropyl)-glycine (DCG IV): a putative positive modulator of metabotropic glutamate receptors coupled to polyphosphoinositide hydrolysis. 55
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids 55
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death. 54
Thyrotropin releasing hormone (TRH) and its analog, RGH-2202, accelerate maturation of cerebellar neurons in vitro. 54
null 54
Protective action of idebenone against excitotoxic degeneration in cultured cortical neurons. 54
Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes 54
Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus 54
null 54
Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo 53
The preferential. mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy 53
SYSTEMICALLY ADMINISTERED D-GLUCOSE CONJUGATES OF 7-CHLOROKYNURETIC ACID ARE CENTRALLY AVAILABLE AND EXERT ANTICONVULSANT ACTIVITY IN RODENTS 53
GABAergic drugs become neurotoxic in cortical neurons pre-exposed to brain-derived neurotrophic factor. 53
null 53
Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Contributes to the Development of Nigro-Striatal Damage Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice 53
Induction of Dickkopf-1, a negative modulator of the wnt pathway, is required for the development of ischemic neuronal death 52
Indolpyruvic acid (IPA) acts as an antagonist of Mg2+-sensitive glutamate receptors in cerebellar neurons 52
Synthesis, pharmacokinetics and anticonvulsant activity of 7-chlorokynurenic acid prodrugs 52
Totale 7.058
Categoria #
all - tutte 46.221
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.221


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.767 0 0 0 0 0 245 281 302 279 256 341 63
2020/2021861 99 97 53 101 27 68 11 122 99 92 69 23
2021/20222.504 27 184 259 44 357 44 50 274 198 211 311 545
2022/20232.481 561 571 63 256 288 246 13 139 185 25 89 45
2023/20241.322 99 142 44 75 115 296 9 75 7 151 96 213
2024/20251.060 85 148 164 59 260 344 0 0 0 0 0 0
Totale 13.078