Catalogo dei prodotti della ricerca

GIANNINI, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 10.177
AS - Asia 5.313
EU - Europa 5.153
SA - Sud America 706
Continente sconosciuto - Info sul continente non disponibili 583
AF - Africa 248
OC - Oceania 10
AN - Antartide 1
Totale 22.191
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Nazione #
US - Stati Uniti d'America 9.922
IT - Italia 2.782
SG - Singapore 1.780
CN - Cina 884
HK - Hong Kong 749
VN - Vietnam 743
DE - Germania 563
BR - Brasile 536
IN - India 439
FI - Finlandia 365
SE - Svezia 318
BD - Bangladesh 245
FR - Francia 191
GB - Regno Unito 177
UA - Ucraina 167
CA - Canada 151
RU - Federazione Russa 137
ZA - Sudafrica 81
AT - Austria 71
JP - Giappone 67
ID - Indonesia 66
AR - Argentina 63
NL - Olanda 58
BG - Bulgaria 50
MA - Marocco 48
IQ - Iraq 44
IE - Irlanda 41
TR - Turchia 40
MX - Messico 36
ES - Italia 35
BE - Belgio 33
TG - Togo 31
KR - Corea 30
PK - Pakistan 27
PL - Polonia 26
SA - Arabia Saudita 26
CH - Svizzera 25
RO - Romania 25
EC - Ecuador 23
CL - Cile 21
DZ - Algeria 20
VE - Venezuela 19
EG - Egitto 17
JM - Giamaica 17
CO - Colombia 15
CZ - Repubblica Ceca 15
CI - Costa d'Avorio 14
LB - Libano 14
MY - Malesia 14
PH - Filippine 14
AE - Emirati Arabi Uniti 13
LT - Lituania 13
UZ - Uzbekistan 13
JO - Giordania 12
PT - Portogallo 12
TH - Thailandia 12
KE - Kenya 11
KZ - Kazakistan 11
CR - Costa Rica 10
HR - Croazia 10
TW - Taiwan 10
AU - Australia 9
NI - Nicaragua 9
TN - Tunisia 9
BO - Bolivia 8
IL - Israele 8
IR - Iran 8
PY - Paraguay 7
AL - Albania 6
AZ - Azerbaigian 6
HN - Honduras 6
HU - Ungheria 6
NP - Nepal 6
OM - Oman 6
PA - Panama 6
PE - Perù 6
PS - Palestinian Territory 6
UY - Uruguay 6
GR - Grecia 5
TT - Trinidad e Tobago 5
BB - Barbados 4
AO - Angola 3
BY - Bielorussia 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
EE - Estonia 3
GE - Georgia 3
QA - Qatar 3
RS - Serbia 3
SC - Seychelles 3
AM - Armenia 2
BH - Bahrain 2
CG - Congo 2
ET - Etiopia 2
EU - Europa 2
KG - Kirghizistan 2
LV - Lettonia 2
MV - Maldive 2
NO - Norvegia 2
PR - Porto Rico 2
Totale 21.581
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Città #
Ashburn 1.279
Rome 1.161
Singapore 989
Fairfield 969
Hong Kong 716
San Jose 622
Chandler 498
Woodbridge 466
Seattle 412
Houston 340
Cambridge 303
Dallas 300
Wilmington 283
Los Angeles 280
Ann Arbor 252
Milan 251
Dearborn 250
Ho Chi Minh City 230
New York 220
Munich 209
Beijing 199
Hanoi 183
Helsinki 170
Princeton 147
Santa Clara 144
San Paolo di Civitate 126
Hillsboro 124
The Dalles 112
Lawrence 105
Plano 105
Lauterbourg 96
Buffalo 95
Frankfurt am Main 90
Council Bluffs 81
Turku 79
Grafing 73
San Diego 72
Boardman 71
Boston 68
Millbury 67
Johannesburg 64
Fremont 55
Vienna 52
Jacksonville 50
Tokyo 50
Sofia 49
Toronto 49
São Paulo 48
Naples 44
Bremen 43
Jakarta 43
Montreal 41
Casablanca 40
Andover 39
Columbus 39
Dublin 39
Cosenza 38
Da Nang 37
Phoenix 36
Des Moines 35
Guangzhou 35
Hefei 35
London 35
Moscow 34
Atlanta 32
Lomé 31
Figino 30
Redondo Beach 30
Falkenstein 29
Haiphong 29
Orem 29
Chicago 26
Chennai 25
Nuremberg 24
Norwalk 23
Clementon 22
Federal 22
Washington 22
Bengaluru 21
Redwood City 21
Lappeenranta 20
Shanghai 19
Berlin 18
Latina 18
Warsaw 18
Brussels 17
Hải Dương 17
Arezzo 15
Baghdad 15
Falls Church 15
Miano 15
Ottawa 15
Tianjin 15
Abidjan 14
Amsterdam 14
Istanbul 14
Manchester 14
Palermo 14
Turin 14
Denver 13
Totale 13.997
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Nome #
MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation 383
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation 293
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer 290
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene 276
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors 269
Circulating Cancer-Associated Macrophage-like Cells as a Blood-Based Biomarker of Response to Immune Checkpoint Inhibitors 259
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module 245
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP 244
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma 237
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer 237
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation 227
Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup 220
Identification of novel BRCA1 large genomic rearrangements by a computational algorithm of amplicon-based Next-Generation Sequencing data 218
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 216
Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer 215
IFN-α neutralizing antibodies distinguish LADA from early-onset type 1 diabetes 213
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma 213
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance 213
Next-generation sequencing of BRCA1 and BRCA2 genes for rapid detection of germline mutations in hereditary breast/ovarian cancer 209
RAS mutation conversion in bevacizumab-treated metastatic colorectal cancer patients: a liquid biopsy based study 204
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer. A novel mechanism of intrinsic drug resistance 203
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness 199
Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer. 198
A multidisciplinary approach for the differential diagnosis between multiple primary lung adenocarcinomas and intrapulmonary metastases 198
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors 196
Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology 195
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress 195
Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer 195
Insight into genetic susceptibility to male breast cancer by multigene panel testing: results from a multicenter study in Italy 195
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors 193
Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy 193
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress 193
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma 192
Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production 191
962: Association of SULT1A1 Arg213His polymorphism with male breast cancer risk: a case−control study in Italy 191
961: Low-penetrance alleles and male breast cancer risk: Results from a multicenter study in Italy 191
Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14. 191
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma 187
Association of SULT1A1 Arg²¹³His polymorphism with male breast cancer risk: results from a multicenter study in Italy. 183
True conversions from RAS mutant to RAS wild-type in circulating tumor DNA from metastatic colorectal cancer patients as assessed by methylation and mutational signature 183
Direct correlation between double K-RAS mutation and mucinous carcinoma. A case report 180
Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families 171
Coexistence of three EGFR mutations in an NSCLC patient: A brief report 171
Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy 170
Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk 166
A single-cell transcriptomic analysis of Neuroblastomas revealed a selective cGAS-STING pathway suppression in malignant cells 164
A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer 160
Improving the accuracy of BRCA1/2 mutation prediction: validation of the novel country-customized IC software. 159
733 Common Breast Cancer Susceptibility Alleles in BRCA-positive and BRCA-negative Male Breast Cancer 159
Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: Results from a multicenter study in Italy 155
Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer 155
Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families 154
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy 154
The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond 151
MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells 151
A LYMPHOTACTIN-PRODUCING MONOCLONAL T-CELL LYMPHOPROLIFERATIVE DISORDER WITH EXTREME LYMPHOCYTOPENIA AND PROGRESSIVE LEUKOENCEPHALOPATHY 150
BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy 148
Effective treatment of a platinum-resistant cutaneous squamous cell carcinoma case by EGFR pathway inhibition 148
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma 147
The role of peroxiredoxins in cancer 146
BRCA1 and BRCA2 genetic testing in Italian breast and/or ovarian cancer families: mutation spectrum and prevalence and analysis of mutation prediction models 146
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 146
The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering. 144
Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis 143
Male breast cancer risk associated with pathogenic variants in genes other than BRCA1/2: an Italian case-control study 141
Impact of SARS-CoV-2 vaccination on FcγRIIIA/CD16 dynamics in Natural Killer cells: relevance for antibody-dependent functions 141
2-Aminopurine unravels a role for pRB in the regulation of gene expression by transforming growth factor beta. 141
Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome. 140
BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases 139
Comparison of two blood-based genotyping tests to investigate the KRAS G12C mutation in patients with non-small-cell lung cancer at failure of first-line treatments 139
PALB2 mutations in male breast cancer: a population-based study in Central Italy 138
Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: A case report 138
EGF- and cell-cycle-regulated STAG1/PMEPA1 ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer 137
Molecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille's heel to be exploited for the therapy of MYCN-amplified neuroblastoma. 137
An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy 136
SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation 135
Circulating tumor cells: Exploring intratumor heterogeneity of colorectal cancer 135
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination 134
Galectin-3 Impairment of MYCN-Dependent Apoptosis-Sensitive Phenotype Is Antagonized by Nutlin-3 in Neuroblastoma Cells 134
Candidate genetic modifiers for breast and ovarian cancer risk inBRCA1andBRCA2 mutation carriers 133
A MYCN-MRN complex axis controls replication stress for the safe expansion of neuroprogenitor cells 132
Matched germline and tumor profiling in male breast cancer for the discovery of molecular subtypes with clinical relevance 132
DELAYED AND DEFECTIVE ANTI-HIV IGM RESPONSE IN INFANTS 132
Prevalence of BRCA1 and BRCA2 genomic rearrangements in a cohort of consecutive Italian breast and/or ovarian cancer families 130
HE4 in the differential diagnosis of a pelvic mass: A case report 130
Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations 130
Numb is a suppressor of Hedgehog signaling and targets Gli1 for Itch-dependent ubiquitination. 130
EGF regulates a complex pattern of gene expression and represses smooth muscle differentiation during the neurotypic conversion of the neural-crest-derived TC-1S cell line 129
Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers 129
BRCA1 and BRCA2: The genetic testing and the current management options for mutation carriers 128
MYCN Sensitizes Human Neuroblastoma to Apoptosis by HIPK2 Activation through a DNA Damage Response 128
The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1 128
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of modifiers of BRCA1/2 128
THE RYANODINE RECEPTOR CALCIUM-CHANNEL GENES ARE WIDELY AND DIFFERENTIALLY EXPRESSED IN MURINE BRAIN AND PERIPHERAL-TISSUES 127
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer 127
HMGA molecules in neuroblastic tumors 126
Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: Results from a collaborative multicenter study in Italy 126
Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability 125
Clinical classification of BRCA1 DNA missense variants: H1686Q is a novel pathogenic mutation occurring in the ontogenetically invariant THV motif of the N-terminal BRCT domain 124
Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells 124
Totale 17.244
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Categoria #
all - tutte 61.641
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 335
selected - selezionate 0
volume - volumi 0
Totale 61.976
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.555 0 85 146 86 172 44 53 159 100 93 350 267
2022/20231.875 300 433 125 187 196 175 56 113 157 27 66 40
2023/20241.443 67 105 87 84 153 307 111 114 12 149 128 126
2024/20253.763 89 102 167 182 188 274 312 265 514 335 368 967
2025/20268.063 785 410 815 697 800 419 1.236 337 539 960 514 551
2026/2027749 372 377 0 0 0 0 0 0 0 0 0 0
Totale 22.191