GIANNINI, Giuseppe
 Distribuzione geografica
Continente #
NA - Nord America 6.218
EU - Europa 2.473
AS - Asia 771
AF - Africa 36
SA - Sud America 27
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.531
Nazione #
US - Stati Uniti d'America 6.171
IT - Italia 1.335
SE - Svezia 306
SG - Singapore 291
IN - India 261
DE - Germania 188
CN - Cina 173
FI - Finlandia 156
UA - Ucraina 149
GB - Regno Unito 65
AT - Austria 47
BG - Bulgaria 46
FR - Francia 43
CA - Canada 42
TG - Togo 31
IE - Irlanda 28
BE - Belgio 27
AR - Argentina 22
RO - Romania 22
NL - Olanda 17
CH - Svizzera 14
HK - Hong Kong 11
CZ - Repubblica Ceca 9
IR - Iran 7
ES - Italia 5
AU - Australia 4
KZ - Kazakistan 4
MX - Messico 4
PK - Pakistan 4
JP - Giappone 3
LT - Lituania 3
MY - Malesia 3
ZA - Sudafrica 3
AL - Albania 2
EU - Europa 2
HR - Croazia 2
IL - Israele 2
PH - Filippine 2
PL - Polonia 2
RU - Federazione Russa 2
TR - Turchia 2
VN - Vietnam 2
AE - Emirati Arabi Uniti 1
BD - Bangladesh 1
BO - Bolivia 1
BR - Brasile 1
BY - Bielorussia 1
CL - Cile 1
DK - Danimarca 1
EC - Ecuador 1
JO - Giordania 1
KG - Kirghizistan 1
LU - Lussemburgo 1
LV - Lettonia 1
MA - Marocco 1
PA - Panama 1
PE - Perù 1
RS - Serbia 1
SA - Arabia Saudita 1
SC - Seychelles 1
TW - Taiwan 1
Totale 9.531
Città #
Fairfield 966
Rome 573
Ashburn 513
Chandler 498
Woodbridge 466
Seattle 409
Houston 334
Cambridge 302
Wilmington 282
Ann Arbor 252
Dearborn 250
Singapore 170
Princeton 147
New York 129
San Paolo di Civitate 126
Lawrence 105
Plano 102
Beijing 75
Grafing 73
San Diego 69
Millbury 67
Boardman 60
Boston 60
Helsinki 57
Fremont 53
Milan 53
Jacksonville 48
Sofia 46
Bremen 43
Vienna 43
Andover 39
Lomé 31
Des Moines 29
Dublin 28
Los Angeles 23
Norwalk 23
Federal 22
Redwood City 21
Toronto 21
Santa Clara 20
Phoenix 17
Washington 16
Arezzo 15
Brussels 15
Falls Church 15
Hefei 14
Naples 12
Auburn Hills 11
Hong Kong 11
Mannheim 11
Ottawa 11
Centrale 10
Lappeenranta 10
San Benedetto del Tronto 10
Bolzano Vicentino 9
Fiuggi 9
Jinan 9
Kunming 9
Nanjing 9
Prague 9
Bühl 8
Chennai 8
Waanrode 8
Castellana Sicula 7
London 7
San Mateo 7
Guangzhou 6
Nanchang 6
Onex 6
Palermo 6
Pisa 6
Benevento 5
Bethesda 5
Buffalo 5
Genoa 5
Montesilvano Marina 5
Sacramento 5
Amsterdam 4
Cerveteri 4
Changsha 4
Florence 4
Frosinone 4
Fuzhou 4
Genzano di Roma 4
Montréal 4
Trieste 4
Turin 4
Velletri 4
Verona 4
Würzburg 4
Basel 3
Cardiff 3
Castelfidardo 3
Chengdu 3
Gunzenhausen 3
Hebei 3
Indiana 3
Montreal 3
Muizenberg 3
Parma 3
Totale 7.047
Nome #
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer 144
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP 127
Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer. 121
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma 117
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer 114
Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families 111
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors 110
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress 109
Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production 109
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance 106
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors 104
Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup 103
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module 103
Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer 102
Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy 102
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 102
Direct correlation between double K-RAS mutation and mucinous carcinoma. A case report 101
PALB2 mutations in male breast cancer: a population-based study in Central Italy 100
Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome. 100
Association of SULT1A1 Arg²¹³His polymorphism with male breast cancer risk: results from a multicenter study in Italy. 100
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation 97
BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy 97
Insight into genetic susceptibility to male breast cancer by multigene panel testing: results from a multicenter study in Italy 97
962: Association of SULT1A1 Arg213His polymorphism with male breast cancer risk: a case−control study in Italy 97
Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy 95
Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14. 93
Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: Results from a multicenter study in Italy 90
Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer 90
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation 90
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors 89
Next-generation sequencing of BRCA1 and BRCA2 genes for rapid detection of germline mutations in hereditary breast/ovarian cancer 88
Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families 87
A LYMPHOTACTIN-PRODUCING MONOCLONAL T-CELL LYMPHOPROLIFERATIVE DISORDER WITH EXTREME LYMPHOCYTOPENIA AND PROGRESSIVE LEUKOENCEPHALOPATHY 86
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness 86
MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells 85
Improving the accuracy of BRCA1/2 mutation prediction: validation of the novel country-customized IC software. 84
Coexistence of three EGFR mutations in an NSCLC patient: A brief report 83
Identification of novel BRCA1 large genomic rearrangements by a computational algorithm of amplicon-based Next-Generation Sequencing data 83
Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology 82
A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer 82
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 82
EXPRESSION OF A RYANODINE RECEPTOR-CA2+ CHANNEL THAT IS REGULATED BY TGF-BETA 81
A MYCN-MRN complex axis controls replication stress for the safe expansion of neuroprogenitor cells 81
Effective treatment of a platinum-resistant cutaneous squamous cell carcinoma case by EGFR pathway inhibition 81
MUC gene abnormalities in sporadic and hereditary mucinous colon cancers with Microsatellite Instability 81
Thrombospondin-1 is a mediator of the neurotypic differentiation induced by EGF in thymic epithelial cells 81
The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1 81
733 Common Breast Cancer Susceptibility Alleles in BRCA-positive and BRCA-negative Male Breast Cancer 81
Molecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille's heel to be exploited for the therapy of MYCN-amplified neuroblastoma. 80
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma 79
THE RYANODINE RECEPTOR CALCIUM-CHANNEL GENES ARE WIDELY AND DIFFERENTIALLY EXPRESSED IN MURINE BRAIN AND PERIPHERAL-TISSUES 79
961: Low-penetrance alleles and male breast cancer risk: Results from a multicenter study in Italy 79
The role of peroxiredoxins in cancer 78
BRCA1 and BRCA2: The genetic testing and the current management options for mutation carriers 77
BRCA1 and BRCA2 genetic testing in Italian breast and/or ovarian cancer families: mutation spectrum and prevalence and analysis of mutation prediction models 77
Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: A case report 77
Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer 76
Prevalence of BRCA1 and BRCA2 genomic rearrangements in a cohort of consecutive Italian breast and/or ovarian cancer families 76
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma 76
Numb is a suppressor of Hedgehog signaling and targets Gli1 for Itch-dependent ubiquitination. 76
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma 75
EGF- and cell-cycle-regulated STAG1/PMEPA1 ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer 75
Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells 75
Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis 75
Candidate genetic modifiers for breast and ovarian cancer risk inBRCA1andBRCA2 mutation carriers 72
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress 72
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination 71
Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation. 71
Does the search for large genomic Rearrangements impact BRCAPRO carrier prediction? 71
DELAYED AND DEFECTIVE ANTI-HIV IGM RESPONSE IN INFANTS 71
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma 69
Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2 and RYR3 by in situ hybridization. 69
Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers 69
Galectin-3 Impairment of MYCN-Dependent Apoptosis-Sensitive Phenotype Is Antagonized by Nutlin-3 in Neuroblastoma Cells 68
Expression of the HMGI(Y) gene products in human neuroblastic tumors correlates with differentiation status 67
EGF regulates a complex pattern of gene expression and represses smooth muscle differentiation during the neurotypic conversion of the neural-crest-derived TC-1S cell line 67
RAS mutation conversion in bevacizumab-treated metastatic colorectal cancer patients: a liquid biopsy based study 67
Clinical classification of BRCA1 DNA missense variants: H1686Q is a novel pathogenic mutation occurring in the ontogenetically invariant THV motif of the N-terminal BRCT domain 66
The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering. 66
2-Aminopurine unravels a role for pRB in the regulation of gene expression by transforming growth factor beta. 65
HMGA molecules in neuroblastic tumors 65
Human MRE11 is inactivated in mismatch repair-deficient cancers 65
HE4 in the differential diagnosis of a pelvic mass: A case report 65
Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability 65
MOLECULAR-STRUCTURE AND TISSUE DISTRIBUTION OF RYANODINE RECEPTORS CALCIUM CHANNELS 64
Molecular mechanism of HMGA1 deregulation in human neuroblastoma 64
BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases 64
MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness 64
Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk 64
Circulating tumor cells: Exploring intratumor heterogeneity of colorectal cancer 63
MRE11 expression is impaired in gastric cancer with microsatellite instability 62
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy 62
The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers 62
cDNA cloning reveals a tissue specific expression of alternatively spliced transcript of the ryanodine receptor type 3 (RyR3) calcium release channel. 62
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer. A novel mechanism of intrinsic drug resistance 61
Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors 61
RELATIVE INCREASE OF T-CELLS EXPRESSING THE GAMMA-DELTA RATHER THAN THE ALPHA-BETA RECEPTOR IN ATAXIA TELANGIECTASIA 61
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of modifiers of BRCA1/2 61
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene 60
Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations 60
Totale 8.201
Categoria #
all - tutte 27.468
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 166
selected - selezionate 0
volume - volumi 0
Totale 27.634


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.019 0 0 53 88 203 417 388 279 248 170 83 90
2020/2021892 74 100 46 35 28 110 26 44 104 238 69 18
2021/20221.585 30 85 146 86 172 44 53 159 100 93 350 267
2022/20231.875 300 433 125 187 196 175 56 113 157 27 66 40
2023/20241.443 67 105 87 84 153 307 111 114 12 149 128 126
2024/2025338 89 102 147 0 0 0 0 0 0 0 0 0
Totale 9.954