The epidermal growth factor receptor (EGFR) represents a molecular target for tyrosine kinase inhibitors for non-small cell lung cancer (NSCLC) patients with a mutation in the EGFR gene. Mutations of the EGFR gene that occur at a single position in NSCLC tissue are found as single, whereas two or more mutations on the same allele are poorly detected and investigated.
Coexistence of three EGFR mutations in an NSCLC patient: A brief report / Belardinilli, Francesca; Gradilone, Angela; Gelibter, ALAIN JONATHAN; Zani, Massimo; Occhipinti, Mario; Ferraro, Sergio; Nicolazzo, Chiara; Coppa, Anna; Giannini, Giuseppe. - In: THE INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS. - ISSN 1724-6008. - (2018), p. 1724600818782200. [10.1177/1724600818782200]
Coexistence of three EGFR mutations in an NSCLC patient: A brief report
BELARDINILLI, FRANCESCA;Gradilone, Angela;GELIBTER, ALAIN JONATHAN;ZANI, Massimo;OCCHIPINTI, MARIO;FERRARO, Sergio;Nicolazzo, Chiara;COPPA, Anna;Giannini, Giuseppe
2018
Abstract
The epidermal growth factor receptor (EGFR) represents a molecular target for tyrosine kinase inhibitors for non-small cell lung cancer (NSCLC) patients with a mutation in the EGFR gene. Mutations of the EGFR gene that occur at a single position in NSCLC tissue are found as single, whereas two or more mutations on the same allele are poorly detected and investigated.| File | Dimensione | Formato | |
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