TOTO, ANGELO
 Distribuzione geografica
Continente #
NA - Nord America 2.406
EU - Europa 1.496
AS - Asia 765
SA - Sud America 77
AF - Africa 60
OC - Oceania 50
Totale 4.854
Nazione #
US - Stati Uniti d'America 2.342
IT - Italia 839
SG - Singapore 273
CN - Cina 142
DE - Germania 126
IN - India 108
SE - Svezia 105
GB - Regno Unito 104
CA - Canada 59
RU - Federazione Russa 57
FI - Finlandia 56
AU - Australia 49
BR - Brasile 46
ID - Indonesia 39
HK - Hong Kong 36
TG - Togo 35
KR - Corea 31
FR - Francia 28
JP - Giappone 26
NL - Olanda 24
TR - Turchia 23
AR - Argentina 20
BG - Bulgaria 20
IE - Irlanda 18
TW - Taiwan 16
ES - Italia 15
UA - Ucraina 15
BE - Belgio 14
IR - Iran 14
DK - Danimarca 13
AT - Austria 12
CH - Svizzera 11
IL - Israele 11
PL - Polonia 11
PK - Pakistan 9
RO - Romania 8
TH - Thailandia 7
BD - Bangladesh 6
LT - Lituania 6
EG - Egitto 5
IQ - Iraq 5
EC - Ecuador 4
MX - Messico 4
PE - Perù 4
VN - Vietnam 4
ZA - Sudafrica 4
ZW - Zimbabwe 4
AZ - Azerbaigian 3
DZ - Algeria 3
MY - Malesia 3
CO - Colombia 2
GR - Grecia 2
KE - Kenya 2
LU - Lussemburgo 2
MK - Macedonia 2
NO - Norvegia 2
PT - Portogallo 2
SC - Seychelles 2
TN - Tunisia 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AM - Armenia 1
CZ - Repubblica Ceca 1
ET - Etiopia 1
GE - Georgia 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
NZ - Nuova Zelanda 1
PA - Panama 1
SA - Arabia Saudita 1
SN - Senegal 1
VE - Venezuela 1
Totale 4.854
Città #
Rome 444
Fairfield 323
Singapore 186
Ashburn 168
Chandler 156
Woodbridge 138
Seattle 137
Houston 117
Cambridge 112
Wilmington 111
Santa Clara 81
New York 62
San Paolo di Civitate 51
Princeton 50
Fremont 44
Ann Arbor 43
Beijing 41
Jakarta 39
Lawrence 39
Helsinki 36
Lomé 35
Nuremberg 30
San Diego 30
Millbury 28
Boston 27
Stockholm 27
Southend 26
Plano 23
Milan 22
Falkenstein 20
Sofia 20
Toronto 19
Dublin 17
Ottawa 17
Frankfurt am Main 16
Andover 15
London 15
Madison 14
Baltimore 13
Hong Kong 13
Los Angeles 13
Brisbane 12
Moscow 12
Avezzano 10
Boardman 10
San Mateo 10
Dearborn 9
Federal 9
Montreal 9
Sydney 9
Warsaw 9
Canberra 8
Council Bluffs 8
Guangzhou 8
Istanbul 8
Munich 8
Shanghai 8
Vienna 8
Ankara 7
Brussels 7
Buenos Aires 7
Copenhagen 7
Decatur 7
Melbourne 7
Perth 7
Philadelphia 7
Piscataway 7
San Jose 7
Tehran 7
Tempe 7
Tokyo 7
Yubileyny 7
Cagliari 6
Falls Church 6
Grotteria 6
Lappeenranta 6
Mannheim 6
Nanjing 6
San Francisco 6
Seongdong-gu 6
Worcester 6
Amsterdam 5
Athens 5
Berlin 5
Bethesda 5
Champaign 5
East Norwich 5
El Cerrito 5
Irvine 5
Jerusalem 5
Latina 5
Norwalk 5
Osaka 5
Oxford 5
Pittsburgh 5
St Louis 5
Yuseong-gu 5
Belo Horizonte 4
Bengaluru 4
Berkeley 4
Totale 3.217
Nome #
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic variant interpretation methods. 967
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor 131
Targeting the interaction between the SH3 domain of Grb2 and Gab2 127
Characterization of human frataxin missense variants in cancer tissues 120
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state 113
The kinetics of folding of the NSH2 domain from p85 110
Ligand binding to the pdz domains of postsynaptic density protein 95 96
The folding pathway of the KIX domain 96
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate 96
Molecular recognition by templated folding of an intrinsically disordered protein 87
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein 84
The folding mechanism of the SH3 domain from Grb2 79
Activation barrier-limited folding and conformational sampling of a dynamic protein domain 78
Regulation of the human phosphatase ptpn4 by the inter-domain linker connecting the pdz and the phosphatase domains 77
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85 76
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer 75
Double mutant cycles as a tool to address folding, binding, and allostery 74
Understanding the effect of alternative splicing in the folding and function of the second pdz from protein tyrosine phosphatase-bl 73
Mechanism of folding and binding of the n-terminal SH2 domain from SHP2 73
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD 73
On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains 73
The kinetics of folding of frataxin. 72
Biophysical characterization of the binding mechanism between the MATH domain of SPOP and its physiological partners 71
Mapping the allosteric network within a SH3 domain 71
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity 70
Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering 67
Folding and misfolding of a PDZ tandem repeat 67
Probing the effects of local frustration in the folding of a multidomain protein 67
Mutational analysis of the binding-induced folding reaction of the mixed-lineage leukemia protein to the KIX domain. 66
The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb. 66
Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein. 64
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 64
Folding and binding mechanisms of the SH2 domain from Crkl 64
Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2 63
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system. 61
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls 61
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains 60
Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2 58
Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes 58
The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor 57
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators 56
The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain 56
Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2 56
Understanding the mechanism of recognition of gab2 by the n-sh2 domain of shp2 56
Characterization of early and late transition states of the folding pathway of a SH2 domain 55
Understanding the role of phosphorylation in the binding mechanism of a PDZ domain 53
Templated folding of intrinsically disordered proteins 53
Demonstration of binding induced structural plasticity in a sh2 domain 52
null 51
An intramolecular energetic network regulates ligand recognition in a SH2 domain 45
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands 44
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 44
Unveiling binding induced folding in intrinsically denatured proteins: a study on the KIX domain and its ligands. 44
Exploring the effect of tethered domains on the folding of Grb2 protein 42
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins 42
SH2 Domains: folding, binding and therapeutical approaches 41
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g 41
Folding and binding kinetics of the tandem of SH2 domains from SHP2 38
Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD 37
null 32
GRB2: A dynamic adaptor protein orchestrating cellular signaling in health and disease 31
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1 28
The cooperative folding of annexin A2 relies on a transient nonnative intermediate 27
Addressing the binding mechanism of the Meprin and TRAF-C hmology domain of the Speckle-Type POZ protein using protein engineering 24
A PDZ tandem repeat folds and unfolds via different pathways 18
PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2 15
null 11
The mechanism of folding of human frataxin in comparison to the yeast homologue – broad energy barriers and the general properties of the transition state 11
Understanding binding-induced folding by temperature jump 9
Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein 3
The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light Chains 2
Totale 5.122
Categoria #
all - tutte 17.008
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.008


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020195 0 0 0 0 0 0 0 0 74 56 35 30
2020/2021410 28 42 48 36 9 48 18 34 39 57 29 22
2021/2022616 49 21 56 23 66 52 20 57 50 49 70 103
2022/2023699 94 161 43 39 73 70 4 48 88 13 31 35
2023/20241.101 44 54 51 48 52 83 16 94 101 210 206 142
2024/20251.359 127 142 119 216 205 191 156 198 5 0 0 0
Totale 5.122