TOTO, ANGELO
 Distribuzione geografica
Continente #
NA - Nord America 2.005
EU - Europa 1.020
AS - Asia 351
AF - Africa 45
OC - Oceania 25
SA - Sud America 15
Totale 3.461
Nazione #
US - Stati Uniti d'America 1.960
IT - Italia 668
IN - India 102
CN - Cina 87
SE - Svezia 81
GB - Regno Unito 66
SG - Singapore 64
CA - Canada 43
DE - Germania 41
FI - Finlandia 36
TG - Togo 35
AU - Australia 25
FR - Francia 23
BG - Bulgaria 20
HK - Hong Kong 16
IE - Irlanda 15
KR - Corea 15
TR - Turchia 13
UA - Ucraina 13
AR - Argentina 11
ES - Italia 11
JP - Giappone 11
PL - Polonia 9
CH - Svizzera 8
IR - Iran 8
RO - Romania 8
TW - Taiwan 8
IL - Israele 7
PK - Pakistan 7
DK - Danimarca 5
BE - Belgio 3
BR - Brasile 3
IQ - Iraq 3
NL - Olanda 3
ZA - Sudafrica 3
AT - Austria 2
DZ - Algeria 2
EG - Egitto 2
LU - Lussemburgo 2
MX - Messico 2
SC - Seychelles 2
TH - Thailandia 2
AL - Albania 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
PT - Portogallo 1
UZ - Uzbekistan 1
VN - Vietnam 1
Totale 3.461
Città #
Rome 364
Fairfield 323
Chandler 156
Ashburn 153
Woodbridge 138
Seattle 134
Houston 115
Wilmington 111
Cambridge 106
San Paolo di Civitate 51
Princeton 50
New York 46
Fremont 44
Beijing 40
Lawrence 39
Ann Arbor 38
Lomé 35
San Diego 29
Millbury 28
Southend 26
Plano 23
Singapore 23
Boston 22
Sofia 20
Helsinki 19
Andover 15
Toronto 15
Dublin 14
Brisbane 11
Milan 11
Ottawa 11
San Mateo 10
Dearborn 9
Federal 9
London 9
Hong Kong 8
Montreal 8
Avezzano 7
Baltimore 7
Warsaw 7
Cagliari 6
Decatur 6
Falls Church 6
Guangzhou 6
Los Angeles 6
Nanjing 6
Perth 6
Philadelphia 6
Shanghai 6
Tehran 6
Ankara 5
East Norwich 5
Istanbul 5
Madison 5
Mannheim 5
Norwalk 5
Bengaluru 4
Canberra 4
Frankfurt am Main 4
Granada 4
Hebei 4
Jacksonville 4
Pomezia 4
San Jose 4
Seongdong-gu 4
Stockholm 4
Taichung 4
The Bronx 4
Ardea 3
Bethesda 3
Brescia 3
Brighton 3
Cape Town 3
Council Bluffs 3
Gloucester 3
Jerusalem 3
Kirkuk 3
Lappeenranta 3
Lyngby 3
Mainz 3
Mumbai 3
Munich 3
Naples 3
Padula 3
Palestrina 3
Ponte Vedra 3
Pontelandolfo 3
Pune 3
Redwood City 3
St Louis 3
Sydney 3
Tokyo 3
Turin 3
Washington 3
West Springfield 3
Yuseong-gu 3
Zurich 3
Annaba 2
Aprilia 2
Ariccia 2
Totale 2.515
Nome #
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic variant interpretation methods. 437
Characterization of human frataxin missense variants in cancer tissues 110
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state 106
The kinetics of folding of the NSH2 domain from p85 102
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor 102
The folding pathway of the KIX domain 88
Molecular recognition by templated folding of an intrinsically disordered protein 84
Targeting the interaction between the SH3 domain of Grb2 and Gab2 80
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate 77
The folding mechanism of the SH3 domain from Grb2 75
Regulation of the human phosphatase ptpn4 by the inter-domain linker connecting the pdz and the phosphatase domains 70
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85 70
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein 70
Understanding the effect of alternative splicing in the folding and function of the second pdz from protein tyrosine phosphatase-bl 69
The kinetics of folding of frataxin. 68
Activation barrier-limited folding and conformational sampling of a dynamic protein domain 67
Mechanism of folding and binding of the n-terminal SH2 domain from SHP2 67
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity 65
Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering 62
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD 62
Double mutant cycles as a tool to address folding, binding, and allostery 62
Mutational analysis of the binding-induced folding reaction of the mixed-lineage leukemia protein to the KIX domain. 61
Mapping the allosteric network within a SH3 domain 61
The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb. 61
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system. 57
Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein. 57
Ligand binding to the pdz domains of postsynaptic density protein 95 57
Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2 57
Folding and misfolding of a PDZ tandem repeat 56
Probing the effects of local frustration in the folding of a multidomain protein 56
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer 56
On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains 56
The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor 52
Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2 52
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls 51
Understanding the role of phosphorylation in the binding mechanism of a PDZ domain 48
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 48
Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes 48
Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2 47
Demonstration of binding induced structural plasticity in a sh2 domain 46
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains 45
Biophysical characterization of the binding mechanism between the MATH domain of SPOP and its physiological partners 44
Templated folding of intrinsically disordered proteins 44
Understanding the mechanism of recognition of gab2 by the n-sh2 domain of shp2 43
Characterization of early and late transition states of the folding pathway of a SH2 domain 42
Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins 39
Folding and binding mechanisms of the SH2 domain from Crkl 38
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators 36
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins 35
Unveiling binding induced folding in intrinsically denatured proteins: a study on the KIX domain and its ligands. 34
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 31
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands 26
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g 26
The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain 24
SH2 Domains: folding, binding and therapeutical approaches 24
Exploring the effect of tethered domains on the folding of Grb2 protein 22
The cooperative folding of annexin A2 relies on a transient nonnative intermediate 18
Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein 17
An intramolecular energetic network regulates ligand recognition in a SH2 domain 17
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1 16
Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD 9
Addressing the binding mechanism of the Meprin and TRAF-C hmology domain of the Speckle-Type POZ protein using protein engineering 9
Understanding binding-induced folding by temperature jump 9
The mechanism of folding of human frataxin in comparison to the yeast homologue – broad energy barriers and the general properties of the transition state 3
PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2 1
Folding and Binding Kinetics of the Tandem of SH2 Domains from SHP2 1
Totale 3.673
Categoria #
all - tutte 11.203
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.203


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201989 0 0 0 0 0 0 0 0 0 0 0 89
2019/2020623 64 17 11 29 58 67 70 112 74 56 35 30
2020/2021410 28 42 48 36 9 48 18 34 39 57 29 22
2021/2022616 49 21 56 23 66 52 20 57 50 49 70 103
2022/2023699 94 161 43 39 73 70 4 48 88 13 31 35
2023/20241.011 44 54 51 48 52 83 16 94 101 210 206 52
Totale 3.673