TOTO, ANGELO

TOTO, ANGELO  

DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"  

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A PDZ tandem repeat folds and unfolds via different pathways 2024 Pennacchietti, Valeria; di Matteo, Sara; Pagano, Livia; Toplek, Fran Bačić; Stegani, Bruno; Toto, Angelo; Toso, Julian; Puglisi, Elena; Capelli, Riccardo; Di Felice, Mariana; Malagrinò, Francesca; Camilloni, Carlo; Gianni, Stefano
Activation barrier-limited folding and conformational sampling of a dynamic protein domain 2016 Jakob Dogan, *; Toto, Angelo; Eva Andersson, §; Gianni, Stefano; Per Jemth, §
Addressing the binding mechanism of the Meprin and TRAF-C hmology domain of the Speckle-Type POZ protein using protein engineering 2023 Diop, Awa; Pietrangeli, Paola; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano
An intramolecular energetic network regulates ligand recognition in a SH2 domain 2023 Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; Malagrinò, Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo
Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering 2017 Bonetti, Daniela; Troilo, Francesca; Toto, Angelo; Brunori, Maurizio; Longhi, Sonia; Gianni, Stefano
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor 2022 Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD 2019 Toto, A.; Troilo, F.; Visconti, L.; Malagrinò, F.; Bignon, C.; Longhi, Sonia Rachele Agata; Gianni, S.; S,
Biophysical characterization of the binding mechanism between the MATH domain of SPOP and its physiological partners 2023 Diop, Awa; Pietrangeli, Paola; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano
Characterization of early and late transition states of the folding pathway of a SH2 domain 2022 Toto, Angelo; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano
Characterization of human frataxin missense variants in cancer tissues 2019 Petrosino, Maria; Pasquo, Alessandra; Novak, Leonore; Toto, Angelo; Gianni, Stefano; Mantuano, Elide; Veneziano, Liana; Minicozzi, Velia; Pastore, Annalisa; Puglisi, Rita; Capriotti, Emidio; Chiaraluce, Roberta; Consalvi, Valerio
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands 2023 Pennacchietti, Valeria; Pagano, Livia; Malagrinò, Francesca; Diop, Awa; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Pietrangeli, Paola; Toto, Angelo; Gianni, Stefano
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein 2020 Toto, Angelo; Ma, Sana; Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic variant interpretation methods. 2024 Jain, Shantanu; Bakolitsa, Constantina; E Brenner, Steven; Radivojac, Predrag; Moult, John; Repo, Susanna; A Hoskins, Roger; Andreoletti, Gaia; Barsky, Daniel; Chellapan, Ajithavalli; Chu, Hoyin; Dabbiru, Navya; K Kollipara, Naveen; Ly, Melissa; J Neumann, Andrew; R Pal, Lipika; Odell, Eric; Pandey, Gaurav; C Peters-Petrulewicz, Robin; Srinivasan, Rajgopal; F Yee, Stephen; Jyothsna Yeleswarapu, Sri; Zuhl, Maya; Adebali, Ogun; Patra, Ayoti; A Beer, Michael; Hosur, Raghavendra; Peng, Jian; M Bernard, Brady; Berry, Michael; Dong, Shengcheng; P Boyle, Alan; Adhikari, Aashish; Chen, Jingqi; Hu, Zhiqiang; Wang, Robert; Wang, Yaqiong; Miller, Maximilian; Wang, Yanran; Bromberg, Yana; Turina, Paola; Capriotti, Emidio; J Han, James; Ozturk, Kivilcim; Carter, Hannah; Babbi, Giulia; Bovo, Samuele; Di Lena, Pietro; Luigi Martelli, Pier; Savojardo, Castrense; Casadio, Rita; S Cline, Melissa; De Baets, Greet; Bonache, Sandra; Díez, Orland; Gutiérrez-Enríquez, Sara; Fernández, Alejandro; Montalban, Gemma; Ootes, Lars; Özkan, Selen; Padilla, Natàlia; Riera, Casandra; De la Cruz, Xavier; Diekhans, Mark; J Huwe, Peter; Wei, Qiong; Xu, Qifang; L Dunbrack, Roland; Gotea, Valer; Elnitski, Laura; Margolin, Gennady; Fariselli, Piero; V Kulakovskiy, Ivan; J Makeev, Vsevolod; D Penzar, Dmitry; E Vorontsov, Ilya; V Favorov, Alexander; R Forman, Julia; Hasenahuer, Marcia; S Fornasari, Maria; Parisi, Gustavo; Avsec, Ziga; H Çelik, Muhammed; Yen Duong Nguyen, Thi; Gagneur, Julien; Shi, Fang-Yuan; D Edwards, Matthew; Guo, Yuchun; Tian, Kevin; Zeng, Haoyang; K Gifford, David; Göke, Jonathan; Zaucha, Jan; Gough, Julian; S Ritchie, Graham R; Frankish, Adam; M Mudge, Jonathan; Harrow, Jennifer; L Young, Erin; Yu, Yao; D Huff, Chad; Murakami, Katsuhiko; Nagai, Yoko; Imanishi, Tadashi; J Mungall, Christopher; B Jacobsen, Julius O; Kim, Dongsup; Jeong, Chan-Seok; T Jones, David; Jun Li, Mulin; Beleva Guthrie, Violeta; Bhattacharya, Rohit; Chen, Yun-Ching; Douville, Christopher; Fan, Jean; Kim, Dewey; Masica, David; Niknafs, Noushin; Sengupta, Sohini; Tokheim, Collin; N Turner, Tychele; Ting Grace Yeo, Hui; Karchin, Rachel; Shin, Sunyoung; Welch, Rene; Keles, Sunduz; Li, Yue; Kellis, Manolis; Corbi-Verge, Carles; V Strokach, Alexey; M Kim, Philip; E Klein, Teri; Mohan, Rahul; A Sinnott-Armstrong, Nicholas; Wainberg, Michael; Kundaje, Anshul; Gonzaludo, Nina; Y Mak, Angel C; Chhibber, Aparna; K Lam, Hugo Y; Dahary, Dvir; Fishilevich, Simon; Lancet, Doron; Lee, Insuk; Bachman, Benjamin; Katsonis, Panagiotis; C Lua, Rhonald; J Wilson, Stephen; Lichtarge, Olivier; R Bhat, Rajendra; Sundaram, Laksshman; Viswanath, Vivek; Bellazzi, Riccardo; Nicora, Giovanna; Rizzo, Ettore; Limongelli, Ivan; M Mezlini, Aziz; Chang, Ray; Kim, Serra; Lai, Carmen; O'Connor, Robert; Topper, Scott; van den Akker, Jeroen; Y Zhou, Alicia; D Zimmer, Anjali; Mishne, Gilad; R Bergquist, Timothy; R Breese, Marcus; F Guerrero, Rafael; Jiang, Yuxiang; Kiga, Nikki; Li, Biao; Mort, Matthew; A Pagel, Kymberleigh; Pejaver, Vikas; H Stamboulian, Moses; Thusberg, Janita; D Mooney, Sean; Teerakulkittipong, Nuttinee; Cao, Chen; Kundu, Kunal; Yin, Yizhou; Yu, Chen-Hsin; Kleyman, Michael; Lin, Chiao-Feng; Stackpole, Mary; M Mount, Stephen; Eraslan, Gökcen; S Mueller, Nikola; Naito, Tatsuhiko; R Rao, Aliz; R Azaria, Johnathan; Brodie, Aharon; Ofran, Yanay; Garg, Aditi; Pal, Debnath; Hawkins-Hooker, Alex; Kenlay, Henry; Reid, John; J Mucaki, Eliseos; K Rogan, Peter; M Schwarz, Jana; B Searls, David; Rie Lee, Gyu; Seok, Chaok; Krämer, Andreas; Shah, Sohela; V Huang, Chenglai; F Kirsch, Jack; Shatsky, Maxim; Cao, Yue; Chen, Haoran; Karimi, Mostafa; Moronfoye, Oluwaseyi; Sun, Yuanfei; Shen, Yang; Shigeta, Ron; T Ford, Colby; Nodzak, Conor; Uppal, Aneeta; Shi, Xinghua; Joseph, Thomas; Kotte, Sujatha; Rana, Sadhna; Rao, Aditya; G Saipradeep, V; Sivadasan, Naveen; Sunderam, Uma; Stanke, Mario; Su, Andrew; Adzhubey, Ivan; M Jordan, Daniel; Sunyaev, Shamil; Rousseau, Frederic; Schymkowitz, Joost; Van Durme, Joost; V Tavtigian, Sean; Carraro, Marco; Giollo, Manuel; E Tosatto, Silvio C; Adato, Orit; Carmel, Liran; E Cohen, Noa; Fenesh, Tzila; Holtzer, Tamar; Juven-Gershon, Tamar; Unger, Ron; Niroula, Abhishek; Olatubosun, Ayodeji; Väliaho, Jouni; Yang, Yang; Vihinen, Mauno; E Wahl, Mary; Chang, Billy; Chun Chong, Ka; Hu, Inchi; Sun, Rui; Ka Kei Wu, William; Xia, Xiaoxuan; C Zee, Benny; H Wang, Maggie; Wang, Meng; Wu, Chunlei; Lu, Yutong; Chen, Ken; Yang, Yuedong; M Yates, Christopher; Kreimer, Anat; Yan, Zhongxia; Yosef, Nir; Zhao, Huying; Wei, Zhipeng; Yao, Zhaomin; Zhou, Fengfeng; Folkman, Lukas; Zhou, Yaoqi; Daneshjou, Roxana; B Altman, Russ; Inoue, Fumitaka; Ahituv, Nadav; P Arkin, Adam; Lovisa, Federica; Bonvini, Paolo; Bowdin, Sarah; Gianni, Stefano; Mantuano, Elide; Minicozzi, Velia; Novak, Leonore; Pasquo, Alessandra; Pastore, Annalisa; Petrosino, Maria; Puglisi, Rita; Toto, Angelo; Veneziano, Liana; Chiaraluce, Roberta; P Ball, Mad; R Bobe, Jason; M Church, George; Consalvi, Valerio; N Cooper, David; A Buckley, Bethany; B Sheridan, Molly; R Cutting, Garry; Chiara Scaini, Maria; J Cygan, Kamil; M Fredericks, Alger; T Glidden, David; Neil, Christopher; L Rhine, Christy; G Fairbrother, William; Y Alontaga, Aileen; W Fenton, Aron; A Matreyek, Kenneth; M Starita, Lea; M Fowler, Douglas; Löscher, Britt-Sabina; Franke, Andre; I Adamson, Scott; R Graveley, Brenton; W Gray, Joe; J Malloy, Mary; P Kane, John; Kousi, Maria; Katsanis, Nicholas; Schubach, Max; Kircher, Martin; Y Mak, Angel C; F Tang, Paul L; Kwok, Pui-Yan; H Lathrop, Richard; T Clark, Wyatt; K Yu, Guoying; H LeBowitz, Jonathan; Benedicenti, Francesco; Bettella, Elisa; Bigoni, Stefania; Cesca, Federica; Mammi, Isabella; Marino-Buslje, Cristina; Milani, Donatella; Peron, Angela; Polli, Roberta; Sartori, Stefano; Stanzial, Franco; Toldo, Irene; Turolla, Licia; C Aspromonte, Maria; Bellini, Mariagrazia; Leonardi, Emanuela; Liu, Xiaoming; Marshall, Christian; Richard McCombie, W; Elefanti, Lisa; Menin, Chiara; Stephen Meyn, M; Murgia, Alessandra; Y Nadeau, Kari C; L Neuhausen, Susan; L Nussbaum, Robert; Pirooznia, Mehdi; B Potash, James; F Dimster-Denk, Dago; D Rine, Jasper; R Sanford, Jeremy; Snyder, Michael; G Cote, Atina; Sun, Song; W Verby, Marta; Weile, Jochen; P Roth, Frederick; Tewhey, Ryan; C Sabeti, Pardis; Campagna, Joan; M Refaat, Marwan; Wojciak, Julianne; Grubb, Soren; Schmitt, Nicole; Shendure, Jay; B Spurdle, Amanda; J Stavropoulos, Dimitri; A Walton, Nephi; P Zandi, Peter; Ziv, Elad; Burke, Wylie; Chen, Flavia; R Carr, Lawrence; Martinez, Selena; Paik, Jodi; Harris-Wai, Julie; Yarborough, Mark; M Fullerton, Stephanie; A Koenig, Barbara; Mcinnes, Gregory; Shigaki, Dustin; Chandonia, John-Marc; Furutsuki, Mabel; Kasak, Laura; Yu, Changhua; Chen, Rui; Friedberg, Iddo; A Getz, Gad; Cong, Qian; N Kinch, Lisa; Zhang, Jing; V Grishin, Nick; Voskanian, Alin; G Kann, Maricel; Tran, Elizabeth; M Ioannidis, Nilah; M Hunter, Jesse; Udani, Rupa; Cai, Binghuang; A Morgan, Alexander; Sokolov, Artem; M Stuart, Joshua; Minervini, Giovanni; M Monzon, Alexander; Batzoglou, Serafim; J Butte, Atul; S Greenblatt, Marc; K Hart, Reece; Hernandez, Ryan; P Hubbard, Tim J; Kahn, Scott; O'Donnell-Luria, Anne; C Ng, Pauline; Shon, John; Veltman, Joris; M Zook, Justin
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 2022 Malagrinò, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano
Demonstration of binding induced structural plasticity in a sh2 domain 2020 Visconti, Lorenzo; Toto, Angelo; Jarvis, James A.; Troilo, Francesca; Malagrinò, Francesca; De Simone, Alfonso; Gianni, Stefano
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 2021 Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1 2023 Pennacchietti, Valeria; Toto, Angelo
Double mutant cycles as a tool to address folding, binding, and allostery 2021 Pagano, Livia; Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Jemth, Per; Gianni, Stefano
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g 2021 Pagano, L.; Malagrino, F.; Nardella, C.; Gianni, S.; Toto, A.
Exploring the effect of tethered domains on the folding of Grb2 protein 2022 Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano