TOTO, ANGELO
TOTO, ANGELO
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Activation barrier-limited folding and conformational sampling of a dynamic protein domain
2016 Jakob Dogan, *; Toto, Angelo; Eva Andersson, §; Gianni, Stefano; Per Jemth, §
Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering
2017 Bonetti, Daniela; Troilo, Francesca; Toto, Angelo; Brunori, Maurizio; Longhi, Sonia; Gianni, Stefano
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor
2022 Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD
2019 Toto, A.; Troilo, F.; Visconti, L.; Malagrinò, F.; Bignon, C.; Longhi, Sonia Rachele Agata; Gianni, S.; S,
Characterization of early and late transition states of the folding pathway of a SH2 domain
2022 Toto, Angelo; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano
Characterization of human frataxin missense variants in cancer tissues
2019 Petrosino, Maria; Pasquo, Alessandra; Novak, Leonore; Toto, Angelo; Gianni, Stefano; Mantuano, Elide; Veneziano, Liana; Minicozzi, Velia; Pastore, Annalisa; Puglisi, Rita; Capriotti, Emidio; Chiaraluce, Roberta; Consalvi, Valerio
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein
2020 Toto, Angelo; Ma, Sana; Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat
2022 Malagrinò, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano
Demonstration of binding induced structural plasticity in a sh2 domain
2020 Visconti, Lorenzo; Toto, Angelo; Jarvis, James A.; Troilo, Francesca; Malagrinò, Francesca; De Simone, Alfonso; Gianni, Stefano
Determining folding and binding properties of the C-terminal SH2 domain of SHP2
2021 Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo
Double mutant cycles as a tool to address folding, binding, and allostery
2021 Pagano, Livia; Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Jemth, Per; Gianni, Stefano
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g
2021 Pagano, L.; Malagrino, F.; Nardella, C.; Gianni, S.; Toto, A.
Exploring the effect of tethered domains on the folding of Grb2 protein
2022 Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano
Folding and binding mechanisms of the SH2 domain from Crkl
2022 Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano
Folding and misfolding of a PDZ tandem repeat
2021 Visconti, Lorenzo; Malagrinò, Francesca; Troilo, Francesca; Pagano, Livia; Toto, Angelo; Gianni, Stefano
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins
2018 Malgieri, G; D'Abrosca, G; Pirone, L; Toto, A; Palmieri, M; Russo, L; Sciacca, Mfm; Tatè, R; Sivo, V; Baglivo, I; Majewska, R; Coletta, M; Pedone, Pv; Isernia, C; De Stefano, M; Gianni, S; Pedone, Em; Milardi, D; Fattorusso, R.
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate
2020 Gautier, Candice; Troilo, Francesca; Cordier, Florence; Malagrinò, Francesca; Toto, Angelo; Visconti, Lorenzo; Zhu, Yanlei; Brunori, Maurizio; Wolff, Nicolas; Gianni, Stefano
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state
2019 Visconti, L; Malagrinò, F; Broggini, L; De Luca, Cmg; Moda, F; Gianni, S; Ricagno, S; Toto, A.
Ligand binding to the pdz domains of postsynaptic density protein 95
2016 Toto, Angelo; Pedersen, Sw; Karlsson, Oa; Moran, Ge; Andersson, E; Chi, Cn; Strømgaard, K; Gianni, Stefano; Jemth, P.
Mapping the allosteric network within a SH3 domain
2019 Malagrinò, F.; Troilo, F.; Bonetti, D.; Toto, A.; Gianni, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Activation barrier-limited folding and conformational sampling of a dynamic protein domain | 2016 | Jakob Dogan, *; Toto, Angelo; Eva Andersson, §; Gianni, Stefano; Per Jemth, § | |
| Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering | 2017 | Bonetti, Daniela; Troilo, Francesca; Toto, Angelo; Brunori, Maurizio; Longhi, Sonia; Gianni, Stefano | |
| Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor | 2022 | Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano | |
| Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD | 2019 | Toto, A.; Troilo, F.; Visconti, L.; Malagrinò, F.; Bignon, C.; Longhi, Sonia Rachele Agata; Gianni, S.; S, | |
| Characterization of early and late transition states of the folding pathway of a SH2 domain | 2022 | Toto, Angelo; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano | |
| Characterization of human frataxin missense variants in cancer tissues | 2019 | Petrosino, Maria; Pasquo, Alessandra; Novak, Leonore; Toto, Angelo; Gianni, Stefano; Mantuano, Elide; Veneziano, Liana; Minicozzi, Velia; Pastore, Annalisa; Puglisi, Rita; Capriotti, Emidio; Chiaraluce, Roberta; Consalvi, Valerio | |
| Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein | 2020 | Toto, Angelo; Ma, Sana; Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano | |
| Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat | 2022 | Malagrinò, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano | |
| Demonstration of binding induced structural plasticity in a sh2 domain | 2020 | Visconti, Lorenzo; Toto, Angelo; Jarvis, James A.; Troilo, Francesca; Malagrinò, Francesca; De Simone, Alfonso; Gianni, Stefano | |
| Determining folding and binding properties of the C-terminal SH2 domain of SHP2 | 2021 | Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo | |
| Double mutant cycles as a tool to address folding, binding, and allostery | 2021 | Pagano, Livia; Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Jemth, Per; Gianni, Stefano | |
| Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g | 2021 | Pagano, L.; Malagrino, F.; Nardella, C.; Gianni, S.; Toto, A. | |
| Exploring the effect of tethered domains on the folding of Grb2 protein | 2022 | Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano | |
| Folding and binding mechanisms of the SH2 domain from Crkl | 2022 | Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano | |
| Folding and misfolding of a PDZ tandem repeat | 2021 | Visconti, Lorenzo; Malagrinò, Francesca; Troilo, Francesca; Pagano, Livia; Toto, Angelo; Gianni, Stefano | |
| Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins | 2018 | Malgieri, G; D'Abrosca, G; Pirone, L; Toto, A; Palmieri, M; Russo, L; Sciacca, Mfm; Tatè, R; Sivo, V; Baglivo, I; Majewska, R; Coletta, M; Pedone, Pv; Isernia, C; De Stefano, M; Gianni, S; Pedone, Em; Milardi, D; Fattorusso, R. | |
| Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate | 2020 | Gautier, Candice; Troilo, Francesca; Cordier, Florence; Malagrinò, Francesca; Toto, Angelo; Visconti, Lorenzo; Zhu, Yanlei; Brunori, Maurizio; Wolff, Nicolas; Gianni, Stefano | |
| Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state | 2019 | Visconti, L; Malagrinò, F; Broggini, L; De Luca, Cmg; Moda, F; Gianni, S; Ricagno, S; Toto, A. | |
| Ligand binding to the pdz domains of postsynaptic density protein 95 | 2016 | Toto, Angelo; Pedersen, Sw; Karlsson, Oa; Moran, Ge; Andersson, E; Chi, Cn; Strømgaard, K; Gianni, Stefano; Jemth, P. | |
| Mapping the allosteric network within a SH3 domain | 2019 | Malagrinò, F.; Troilo, F.; Bonetti, D.; Toto, A.; Gianni, S. |