TOTO, ANGELO
 Distribuzione geografica
Continente #
NA - Nord America 963
EU - Europa 655
AS - Asia 141
OC - Oceania 19
AF - Africa 14
SA - Sud America 5
Totale 1.797
Nazione #
US - Stati Uniti d'America 932
IT - Italia 297
FR - Francia 146
DE - Germania 38
CN - Cina 32
GB - Regno Unito 31
CA - Canada 27
FI - Finlandia 23
UA - Ucraina 23
NL - Olanda 21
JP - Giappone 20
AU - Australia 18
IN - India 18
SE - Svezia 14
CZ - Repubblica Ceca 13
KR - Corea 12
HK - Hong Kong 11
DK - Danimarca 8
ZA - Sudafrica 8
IR - Iran 7
SG - Singapore 7
TR - Turchia 7
AE - Emirati Arabi Uniti 6
BG - Bulgaria 6
CH - Svizzera 5
ES - Italia 5
IL - Israele 5
HU - Ungheria 4
MX - Messico 4
MY - Malesia 4
AT - Austria 3
BE - Belgio 3
CL - Cile 3
GR - Grecia 3
IE - Irlanda 3
PL - Polonia 3
RO - Romania 3
SA - Arabia Saudita 3
TG - Togo 3
DZ - Algeria 2
ID - Indonesia 2
IQ - Iraq 2
PK - Pakistan 2
TW - Taiwan 2
AR - Argentina 1
BR - Brasile 1
EG - Egitto 1
LT - Lituania 1
LU - Lussemburgo 1
MM - Myanmar 1
NZ - Nuova Zelanda 1
RU - Federazione Russa 1
Totale 1.797
Città #
Rome 157
Fairfield 95
Santa Cruz 93
Ashburn 70
Buffalo 56
Seattle 35
Woodbridge 35
Houston 32
Cambridge 26
Wilmington 23
Council Bluffs 22
Chicago 19
Des Moines 18
Paris 18
Las Vegas 15
Los Angeles 13
San Diego 13
Shanghai 11
Ann Arbor 10
Columbus 10
New York 10
Toronto 10
Amsterdam 9
Helsinki 9
Lappeenranta 9
Cedar Knolls 8
Mountain View 8
Ottawa 8
Tokyo 8
Boardman 7
Ensues-la-Redonne 7
Riva 7
Sydney 7
Henderson 6
Lessolo 6
Muizenberg 6
Sofia 6
Stockholm 6
Dallas 5
Frankfurt am Main 5
Perth 5
Phoenix 5
San Antonio 5
Singapore 5
Acton 4
Andover 4
Atlanta 4
Copenhagen 4
Cremosano 4
Miami 4
Montreal 4
Parma 4
Pomezia 4
Provo 4
Rehovot 4
San Jose 4
Strasbourg 4
Sunnyvale 4
Beijing 3
Bengaluru 3
Chennai 3
Dublin 3
Durango 3
Izmir 3
Jacksonville 3
Jersey City 3
Kampung Sungai Glugur 3
Lausanne 3
Lomé 3
Lyngby 3
Milan 3
Mumbai 3
Munich 3
Nagoya 3
Naples 3
Negrar 3
Nepi 3
New Delhi 3
New Orleans 3
Portland 3
San Francisco 3
Turin 3
Vancouver 3
Warsaw 3
Washington 3
Yongsan 3
Yuseong-gu 3
Aix-en-Provence 2
Annaba 2
Athens 2
Auriol 2
Baltimore 2
Bhopal 2
Bristol 2
Brno 2
Budapest 2
Canberra 2
Central 2
Cheonan 2
Cheyenne 2
Totale 1.107
Nome #
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic variant interpretation methods., file b88a409a-6ddf-461b-97bd-a9f1137857a1 164
SH2 Domains: folding, binding and therapeutical approaches, file e795ec9f-b754-45f0-b33e-409c7cbd624e 101
The kinetics of folding of the NSH2 domain from p85, file e3835320-df46-15e8-e053-a505fe0a3de9 95
Double mutant cycles as a tool to address folding, binding, and allostery, file e3835328-ef3c-15e8-e053-a505fe0a3de9 95
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85, file e3835324-d2ca-15e8-e053-a505fe0a3de9 93
Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins, file e383532b-aff6-15e8-e053-a505fe0a3de9 91
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state, file e383531f-436d-15e8-e053-a505fe0a3de9 86
Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2, file e3835324-d2c9-15e8-e053-a505fe0a3de9 83
Targeting the interaction between the SH3 domain of Grb2 and Gab2, file e3835328-65a3-15e8-e053-a505fe0a3de9 82
Mapping the allosteric network within a SH3 domain, file e3835323-b445-15e8-e053-a505fe0a3de9 74
Regulation of the human phosphatase ptpn4 by the inter-domain linker connecting the pdz and the phosphatase domains, file e3835318-1e88-15e8-e053-a505fe0a3de9 72
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls, file e3835326-40b0-15e8-e053-a505fe0a3de9 67
Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2, file e3835318-0275-15e8-e053-a505fe0a3de9 65
Understanding the mechanism of recognition of gab2 by the n-sh2 domain of shp2, file e3835326-ebab-15e8-e053-a505fe0a3de9 64
Demonstration of binding induced structural plasticity in a sh2 domain, file e3835325-f7f4-15e8-e053-a505fe0a3de9 62
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins, file e383531a-cab9-15e8-e053-a505fe0a3de9 58
Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes, file e383532d-835e-15e8-e053-a505fe0a3de9 54
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor, file e383532e-2da4-15e8-e053-a505fe0a3de9 51
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate, file e3835327-b85d-15e8-e053-a505fe0a3de9 49
Exploring the effect of tethered domains on the folding of Grb2 protein, file e7aa879b-332c-40c7-8b60-aff26431037c 33
Determining folding and binding properties of the C-terminal SH2 domain of SHP2, file e383532d-49f6-15e8-e053-a505fe0a3de9 31
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer, file e383532d-208c-15e8-e053-a505fe0a3de9 30
Characterization of early and late transition states of the folding pathway of a SH2 domain, file e383532f-3559-15e8-e053-a505fe0a3de9 25
The cooperative folding of annexin A2 relies on a transient nonnative intermediate, file 960327a6-447d-49ce-8d46-c262d40811b9 24
Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein, file 8b666bb8-38c2-4f01-b600-3d7501c94bab 20
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands, file c1784792-171a-463c-bb84-eb6f8f5dad8c 16
On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains, file e383532e-5251-15e8-e053-a505fe0a3de9 15
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains, file 2c05d229-c23b-48bc-94b1-faacd91e709f 14
Biophysical characterization of the binding mechanism between the MATH domain of SPOP and its physiological partners, file c58b446d-33ff-4cab-8ef2-b495f03ac742 14
Characterization of human frataxin missense variants in cancer tissues, file e383532b-70cd-15e8-e053-a505fe0a3de9 14
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1, file 5bac1a16-adb9-4669-b6f4-10dea38f9a36 13
Folding and binding mechanisms of the SH2 domain from Crkl, file f00e2e41-3516-4b00-84cd-08c701874b36 13
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g, file e383532d-cb1e-15e8-e053-a505fe0a3de9 12
An intramolecular energetic network regulates ligand recognition in a SH2 domain, file e264e4a9-10ca-4fa0-bffe-3619fc45416d 11
The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain, file 87bb60c4-978b-43eb-97e9-68544a41cb96 6
Addressing the binding mechanism of the Meprin and TRAF-C hmology domain of the Speckle-Type POZ protein using protein engineering, file d63a2ebd-ae17-45d3-9b80-ac4e594ca317 5
The mechanism of folding of human frataxin in comparison to the yeast homologue – broad energy barriers and the general properties of the transition state, file 5c6bd8be-6d4e-4984-97aa-b7c20977e5f8 4
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat, file d7395b11-d096-443f-bfec-82b496fb2da5 4
Characterization of human frataxin missense variants in cancer tissues, file e3835321-e507-15e8-e053-a505fe0a3de9 4
Mutational analysis of the binding-induced folding reaction of the mixed-lineage leukemia protein to the KIX domain., file e3835316-9559-15e8-e053-a505fe0a3de9 3
Molecular recognition by templated folding of an intrinsically disordered protein, file e3835316-b19b-15e8-e053-a505fe0a3de9 3
Activation barrier-limited folding and conformational sampling of a dynamic protein domain, file e3835316-b331-15e8-e053-a505fe0a3de9 3
Understanding the role of phosphorylation in the binding mechanism of a PDZ domain, file e3835317-1243-15e8-e053-a505fe0a3de9 3
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators, file a1266567-afef-4c80-bd57-7b2f43f0a90f 2
Ligand binding to the pdz domains of postsynaptic density protein 95, file e3835316-6f63-15e8-e053-a505fe0a3de9 2
Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering, file e3835318-25f8-15e8-e053-a505fe0a3de9 2
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity, file e383531c-71fb-15e8-e053-a505fe0a3de9 2
The folding mechanism of the SH3 domain from Grb2, file e383531f-1c8d-15e8-e053-a505fe0a3de9 2
Mechanism of folding and binding of the n-terminal SH2 domain from SHP2, file e383531f-4370-15e8-e053-a505fe0a3de9 2
The folding pathway of the KIX domain, file e3835321-9f53-15e8-e053-a505fe0a3de9 2
Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2, file e3835323-b449-15e8-e053-a505fe0a3de9 2
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD, file e3835323-b44b-15e8-e053-a505fe0a3de9 2
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein, file e3835327-a56a-15e8-e053-a505fe0a3de9 2
Probing the effects of local frustration in the folding of a multidomain protein, file e383532c-a5dc-15e8-e053-a505fe0a3de9 2
Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD, file f92730dc-5a85-4d49-b081-811f87cf05fe 2
Understanding the effect of alternative splicing in the folding and function of the second pdz from protein tyrosine phosphatase-bl, file e3835312-c2e0-15e8-e053-a505fe0a3de9 1
Templated folding of intrinsically disordered proteins, file e3835327-4426-15e8-e053-a505fe0a3de9 1
Understanding binding-induced folding by temperature jump, file e3835328-1795-15e8-e053-a505fe0a3de9 1
Folding and misfolding of a PDZ tandem repeat, file e3835329-a391-15e8-e053-a505fe0a3de9 1
Totale 1.854
Categoria #
all - tutte 5.262
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.262


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201913 0 0 0 0 0 0 0 0 0 0 0 13
2019/2020162 9 3 5 3 7 14 20 26 28 18 16 13
2020/2021247 20 24 10 21 9 18 18 17 29 33 27 21
2021/2022358 39 17 20 18 28 18 10 21 18 16 103 50
2022/2023417 22 15 103 52 22 42 15 31 35 18 34 28
2023/2024636 22 22 39 39 61 52 43 56 68 85 104 45
Totale 1.854