Catalogo dei prodotti della ricerca

INFANTE, PAOLA
 Distribuzione geografica
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Continente #
NA - Nord America 2.760
EU - Europa 2.214
AS - Asia 846
SA - Sud America 100
AF - Africa 36
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.963
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Nazione #
US - Stati Uniti d'America 2.699
IT - Italia 1.159
SG - Singapore 403
DE - Germania 300
SE - Svezia 186
CN - Cina 157
FI - Finlandia 143
IN - India 141
BR - Brasile 69
RO - Romania 67
RU - Federazione Russa 59
GB - Regno Unito 54
AT - Austria 49
CA - Canada 41
FR - Francia 36
ID - Indonesia 35
HK - Hong Kong 29
NL - Olanda 24
BG - Bulgaria 22
MX - Messico 19
TG - Togo 19
TR - Turchia 19
BE - Belgio 18
TW - Taiwan 18
UA - Ucraina 17
IE - Irlanda 16
CH - Svizzera 15
AR - Argentina 14
ES - Italia 10
HR - Croazia 10
PK - Pakistan 10
PL - Polonia 8
ZA - Sudafrica 8
CL - Cile 7
KR - Corea 6
LT - Lituania 5
AU - Australia 4
EE - Estonia 4
JP - Giappone 4
CO - Colombia 3
IQ - Iraq 3
KZ - Kazakistan 3
MA - Marocco 3
PE - Perù 3
TH - Thailandia 3
AZ - Azerbaigian 2
BD - Bangladesh 2
CY - Cipro 2
EC - Ecuador 2
EG - Egitto 2
LV - Lettonia 2
MY - Malesia 2
NZ - Nuova Zelanda 2
PH - Filippine 2
PT - Portogallo 2
SC - Seychelles 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BS - Bahamas 1
BY - Bielorussia 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
HU - Ungheria 1
IR - Iran 1
IS - Islanda 1
KG - Kirghizistan 1
LI - Liechtenstein 1
MO - Macao, regione amministrativa speciale della Cina 1
PY - Paraguay 1
RS - Serbia 1
SA - Arabia Saudita 1
TN - Tunisia 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 5.963
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Città #
Rome 523
Fairfield 400
Chandler 251
Singapore 228
Ashburn 222
Seattle 187
Woodbridge 160
Houston 152
Cambridge 146
Wilmington 115
Helsinki 102
Munich 87
San Paolo di Civitate 65
Princeton 64
Santa Clara 60
Dearborn 57
Ann Arbor 49
Lawrence 45
Timisoara 44
Beijing 43
New York 43
Millbury 42
Bremen 39
Vienna 39
Grafing 37
Fremont 36
Plano 36
San Diego 33
Jakarta 32
Florence 30
Milan 29
Cosenza 27
Andover 26
Hong Kong 24
Boston 22
Sofia 21
Toronto 21
Council Bluffs 19
Lomé 19
Siena 17
Dublin 16
Des Moines 15
Kaohsiung City 15
Boardman 14
Brussels 14
London 14
Ciudad Juárez 12
Federal 12
Phoenix 11
Falkenstein 10
Ottawa 10
São Paulo 10
Frankfurt am Main 9
Moscow 9
Nuremberg 9
Trieste 9
Amsterdam 8
Istanbul 8
Latina 8
Yubileyny 8
Zagreb 8
Los Angeles 7
Norwalk 7
Bühl 6
Campomorone 6
Montesilvano Marina 6
Santiago 6
Senigallia 6
Torino 6
Cerveteri 5
Chengdu 5
Fiuggi 5
Genoa 5
Kunming 5
Lappeenranta 5
Naples 5
Nürnberg 5
Pomezia 5
Belo Horizonte 4
Benevento 4
Chongqing 4
Guangzhou 4
Jyväskylä 4
Mannheim 4
Muizenberg 4
Notre Dame 4
Palermo 4
Pune 4
Redwood City 4
Sacramento 4
Tallinn 4
Turin 4
Zurich 4
Arezzo 3
Basel 3
Bengaluru 3
Bursa 3
Castelnuovo di Val di Cecina 3
Centrale 3
Chiswick 3
Totale 3.997
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Nome #
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma 206
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells 169
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma 168
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer 156
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma 149
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth 147
Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth 145
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP 140
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer 137
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module 136
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors 135
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype 133
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation 128
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis 125
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma 121
Targeting GLI factors to inhibit the Hedgehog pathway 118
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint 118
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors 117
Potential of a natural compound as hedgehog pathway inhibitor for the treatment of intrahepatic cholangiocarcinoma 116
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 116
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 109
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 107
Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation 107
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 105
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors 105
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors 103
Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma 100
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth 99
Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection 94
Click reaction as a tool to combine pharmacophores: The case of Vismodegib 93
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 92
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors 92
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress 92
Protected from the inside: Endogenous histone deacetylase inhibitors and the road to cancer 89
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development 86
Multitarget hedgehog pathway inhibitors and uses thereof 85
Insights into gli factors ubiquitylation methods 82
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog 82
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors 81
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i 79
Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch 78
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 76
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal 75
Yin-Yang strands of PCAF/Hedgehog axis in cancer control 72
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy 71
mPEG5kDa-cholane/Glabrescione B delivery system as promising tool for the treatment of Hh-dependent tumors 70
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) 68
GLI1-selective inhibitor, Glabrescione B, impairs proliferation in intrahepatic cholangiocarcinoma 65
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma 64
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma 64
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis 64
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? 62
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer 61
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro 56
Natural Products to Drugs: New Sonic Hedgehog Pathway Inhibitors in Meduloblastoma 49
Dissecting the hindrance of Hedgehog pathway in Intrahepatic Cholangiocarcinoma: a step towards targeted therapy 46
Multitarget hedgehog pathway inhibitors and uses thereof 46
Exploring the potential of anthraquinone-based hybrids for  identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour 45
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples 42
Natural compound as anticancer agent: in vitro experimental evidence in Intrahepatic Cholangiocarcinoma 36
“Natural products as Hedgehog signaling pathway inhibitors” 36
Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma 36
Natural products as Hedgehog signaling pathway inhibitors 35
COMPOUNDS FOR USE IN THE TREATMENT OF BRAIN DISEASES 35
Investigation of GLI1 selective inhibitor for targeted therapy in Intrahepatic Cholangiocarcinoma: a step towards precision medicine 33
“Small molecules derived from plants as Hedgehog signaling pathway inhibitors” 33
First proof-of-concept study on targeting Hedgehog pathway in intrahepatic cholangiocarcinoma histological subtypes 32
Imparing proliferation, survival and invasiveness of Intrahepatic Cholangiocarcinoma through a novel natural Hedgehog pathway inhibitor 32
“Natural lead products inhibit the Hedgehog signaling pathway in medulloblastoma”. 28
Natural products as Hedgehog signaling pathway inhibitors 27
Natural products as Hedgehog signaling pathway inhibitors 26
Targeting Hedgehog signaling pathway by a natural compound: a promising approach for anti-cancer therapeutic development in Intrahepatic Cholangiocarcinoma 19
Totale 6.244
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Categoria #
all - tutte 19.427
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 465
selected - selezionate 0
volume - volumi 0
Totale 19.892
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020183 0 0 0 0 0 0 0 0 0 80 59 44
2020/2021522 39 32 28 13 13 41 56 39 61 139 48 13
2021/2022941 101 41 62 86 87 39 23 82 64 60 184 112
2022/20231.015 154 219 61 136 96 100 31 63 86 12 34 23
2023/2024840 33 58 33 35 90 174 44 102 19 82 68 102
2024/20251.444 47 48 90 172 162 209 218 218 271 9 0 0
Totale 6.244