Catalogo dei prodotti della ricerca

INFANTE, PAOLA
 Distribuzione geografica
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Continente #
NA - Nord America 2.581
EU - Europa 1.609
AS - Asia 434
AF - Africa 32
SA - Sud America 21
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.681
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Nazione #
US - Stati Uniti d'America 2.558
IT - Italia 888
SE - Svezia 186
DE - Germania 180
SG - Singapore 150
IN - India 132
CN - Cina 88
FI - Finlandia 72
RO - Romania 66
AT - Austria 40
GB - Regno Unito 32
FR - Francia 27
BG - Bulgaria 22
CA - Canada 19
TG - Togo 19
UA - Ucraina 17
IE - Irlanda 16
TW - Taiwan 16
HK - Hong Kong 15
AR - Argentina 12
CH - Svizzera 12
BE - Belgio 9
ES - Italia 9
NL - Olanda 9
ZA - Sudafrica 8
RU - Federazione Russa 7
TR - Turchia 7
HR - Croazia 6
KR - Corea 4
PK - Pakistan 4
BR - Brasile 3
CL - Cile 3
KZ - Kazakistan 3
MX - Messico 3
TH - Thailandia 3
AU - Australia 2
BD - Bangladesh 2
CY - Cipro 2
EE - Estonia 2
ID - Indonesia 2
LV - Lettonia 2
MA - Marocco 2
MY - Malesia 2
PE - Perù 2
SC - Seychelles 2
BA - Bosnia-Erzegovina 1
BS - Bahamas 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
EU - Europa 1
HU - Ungheria 1
IQ - Iraq 1
IR - Iran 1
JP - Giappone 1
LT - Lituania 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PL - Polonia 1
PT - Portogallo 1
RS - Serbia 1
Totale 4.681
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Città #
Fairfield 400
Rome 393
Chandler 251
Ashburn 212
Seattle 187
Woodbridge 160
Houston 152
Cambridge 142
Wilmington 115
San Paolo di Civitate 65
Princeton 64
Singapore 61
Dearborn 57
Ann Arbor 49
Lawrence 45
Timisoara 44
Millbury 42
Beijing 41
New York 41
Helsinki 40
Bremen 39
Grafing 37
Fremont 36
Plano 36
Vienna 34
San Diego 33
Andover 26
Milan 26
Boston 22
Sofia 21
Lomé 19
Siena 17
Dublin 16
Des Moines 15
Kaohsiung City 15
Hong Kong 14
Florence 13
Boardman 12
Federal 12
Phoenix 11
Trieste 8
Brussels 7
Norwalk 7
Toronto 7
Amsterdam 6
Bühl 6
Campomorone 6
Istanbul 6
Santa Clara 6
Senigallia 6
Torino 6
Zagreb 6
Fiuggi 5
Genoa 5
Kunming 5
London 5
Nürnberg 5
Pomezia 5
Benevento 4
Cerveteri 4
Mannheim 4
Montesilvano Marina 4
Muizenberg 4
Naples 4
Notre Dame 4
Ottawa 4
Palermo 4
Pune 4
Redwood City 4
Sacramento 4
Arezzo 3
Basel 3
Castelnuovo di Val di Cecina 3
Centrale 3
Chengdu 3
Chiswick 3
Chongqing 3
Colombes 3
Dallas 3
Guangzhou 3
Hefei 3
Indiana 3
Lappeenranta 3
Los Angeles 3
Montreal 3
Montréal 3
Na Mom 3
Nanjing 3
Pescara 3
San Benedetto del Tronto 3
Spring Hill 3
Stockholm 3
Trecastelli 3
Velletri 3
Washington 3
Zurich 3
Albano Laziale 2
Ascoli Piceno 2
Astana 2
Atoka 2
Totale 3.256
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Nome #
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells 156
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer 143
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth 131
Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth 131
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma 126
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP 124
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype 120
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma 118
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer 113
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis 111
Targeting GLI factors to inhibit the Hedgehog pathway 110
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors 109
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint 107
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors 104
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 102
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module 101
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 98
Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation 97
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 96
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors 89
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors 89
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation 88
Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma 88
Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection 84
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 84
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 83
Click reaction as a tool to combine pharmacophores: The case of Vismodegib 81
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth 80
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma 78
Insights into gli factors ubiquitylation methods 78
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development 75
Multitarget hedgehog pathway inhibitors and uses thereof 75
Protected from the inside: Endogenous histone deacetylase inhibitors and the road to cancer 74
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog 74
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress 72
Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch 70
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors 67
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i 66
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors 66
Yin-Yang strands of PCAF/Hedgehog axis in cancer control 65
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 65
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal 64
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy 62
Potential of a natural compound as hedgehog pathway inhibitor for the treatment of intrahepatic cholangiocarcinoma 60
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma 60
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) 60
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma 57
mPEG5kDa-cholane/Glabrescione B delivery system as promising tool for the treatment of Hh-dependent tumors 53
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro 51
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis 49
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer 47
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? 46
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma 44
GLI1-selective inhibitor, Glabrescione B, impairs proliferation in intrahepatic cholangiocarcinoma 41
Multitarget hedgehog pathway inhibitors and uses thereof 37
Natural products as Hedgehog signaling pathway inhibitors 32
“Natural products as Hedgehog signaling pathway inhibitors” 32
Exploring the potential of anthraquinone-based hybrids for  identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour 26
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples 26
Natural Products to Drugs: New Sonic Hedgehog Pathway Inhibitors in Meduloblastoma 25
“Small molecules derived from plants as Hedgehog signaling pathway inhibitors” 25
COMPOUNDS FOR USE IN THE TREATMENT OF BRAIN DISEASES 25
“Natural lead products inhibit the Hedgehog signaling pathway in medulloblastoma”. 24
Natural products as Hedgehog signaling pathway inhibitors 24
Natural compound as anticancer agent: in vitro experimental evidence in Intrahepatic Cholangiocarcinoma 21
Natural products as Hedgehog signaling pathway inhibitors 19
Imparing proliferation, survival and invasiveness of Intrahepatic Cholangiocarcinoma through a novel natural Hedgehog pathway inhibitor 18
Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma 17
Targeting Hedgehog signaling pathway by a natural compound: a promising approach for anti-cancer therapeutic development in Intrahepatic Cholangiocarcinoma 5
Totale 4.938
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Categoria #
all - tutte 14.081
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 342
selected - selezionate 0
volume - volumi 0
Totale 14.423
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020822 0 0 11 40 80 132 161 111 104 80 59 44
2020/2021522 39 32 28 13 13 41 56 39 61 139 48 13
2021/2022941 101 41 62 86 87 39 23 82 64 60 184 112
2022/20231.015 154 219 61 136 96 100 31 63 86 12 34 23
2023/2024840 33 58 33 35 90 174 44 102 19 82 68 102
2024/2025138 47 48 43 0 0 0 0 0 0 0 0 0
Totale 4.938