The present invention concerns compds. that selectively inhibit the activity of the Hedgehog (Hh) pathway, their prepn. and uses thereof. The compds. of the present invention are useful in treating Hh-dependent tumors, such as medulloblastoma (MB).
Multitarget hedgehog pathway inhibitors and uses thereof / Botta, Bruno; Gulino, Alberto; Botta, Maurizio; Mori, Mattia; DI MARCOTULLIO, Lucia; Infante, Paola; Ghirga, Francesca; Toscano, Sara; Ingallina, Cinzia; Alfonsi, Romina. - (2014).
Multitarget hedgehog pathway inhibitors and uses thereof
BOTTA, Bruno;GULINO, Alberto;DI MARCOTULLIO, LUCIA;Infante Paola;GHIRGA, FRANCESCA;TOSCANO, SARA;INGALLINA, CINZIA;ALFONSI, ROMINA
2014
Abstract
The present invention concerns compds. that selectively inhibit the activity of the Hedgehog (Hh) pathway, their prepn. and uses thereof. The compds. of the present invention are useful in treating Hh-dependent tumors, such as medulloblastoma (MB).File allegati a questo prodotto
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