Catalogo dei prodotti della ricerca

DE BLASI, ANTONIO
 Distribuzione geografica
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Continente #
NA - Nord America 4.369
EU - Europa 831
AS - Asia 549
SA - Sud America 20
AF - Africa 8
OC - Oceania 1
Totale 5.778
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Nazione #
US - Stati Uniti d'America 4.350
IT - Italia 280
IN - India 222
SG - Singapore 220
SE - Svezia 170
FI - Finlandia 139
UA - Ucraina 121
CN - Cina 100
DE - Germania 31
GB - Regno Unito 29
IE - Irlanda 24
AR - Argentina 18
CA - Canada 18
BE - Belgio 10
RO - Romania 9
RU - Federazione Russa 7
NL - Olanda 3
TG - Togo 3
ZA - Sudafrica 3
CH - Svizzera 2
GR - Grecia 2
HU - Ungheria 2
ID - Indonesia 2
IR - Iran 2
JP - Giappone 2
SC - Seychelles 2
AU - Australia 1
BG - Bulgaria 1
BR - Brasile 1
CL - Cile 1
FR - Francia 1
IQ - Iraq 1
MX - Messico 1
Totale 5.778
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Città #
Fairfield 777
Woodbridge 341
Ashburn 325
Chandler 282
Houston 280
Seattle 279
Cambridge 264
Wilmington 241
Santa Clara 195
San Paolo di Civitate 193
Princeton 189
Ann Arbor 171
Singapore 153
Plano 117
Lawrence 111
Millbury 101
Beijing 74
San Diego 66
Rome 59
Jacksonville 52
Boardman 32
Andover 31
Helsinki 25
Boston 24
Dublin 23
Norwalk 22
Federal 18
Dearborn 17
Toronto 15
Falkenstein 11
Brussels 10
Mannheim 9
Bühl 7
London 7
San Mateo 6
Indiana 5
Caldogno 4
Falls Church 4
Milan 4
Moscow 4
Shenyang 4
Chiswick 3
Fort Worth 3
Fremont 3
Hefei 3
Kunming 3
Lomé 3
Ottawa 3
Pune 3
Wuhan 3
Aversa 2
Bari 2
Bern 2
Bremen 2
Budapest 2
Des Moines 2
Flushing 2
Fuzhou 2
Guastameroli 2
Henderson 2
Hounslow 2
Jakarta 2
Leawood 2
Leicester 2
Nanjing 2
Phoenix 2
Romola 2
Springfield 2
Trumbull 2
Umeda 2
Washington 2
Acton 1
Baghdad 1
Buffalo 1
DeKalb 1
Friesland 1
Guangzhou 1
Gunzenhausen 1
Langfang 1
Los Angeles 1
Los Lunas 1
Mcallen 1
Melbourne 1
Modderfontein 1
Muizenberg 1
Mumbai 1
Nanning 1
Nenagh 1
New Bedfont 1
New York 1
Portici 1
Portland 1
Prescot 1
Prineville 1
Provo 1
Puebla City 1
Redmond 1
Redwood City 1
Sacramento 1
Saint Louis 1
Totale 4.650
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Nome #
Xanthurenic Acid Activates mGlu2/3 metabotropic glutamate receptors and is a potential trait marker for schizophrenia 121
BDNF rs6265 methylation and genotype interact on risk for schizophrenia 101
Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus 97
G protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications 93
Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins. 89
The platelet maximum number of A2A-receptor binding sites (Bmax) linearly correlates with age at onset and CAG repeat expansion in Huntington's disease patients with predominant chorea. 89
Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity. 84
Amphetamines induce ubiquitin-positive inclusions within striatal cells 81
BETA-ADRENERGIC RECEPTORS ON MNL 80
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways 78
Continuous subcutaneous infusion of apomorphine rescues nigro-striatal dopaminergic terminals following MPTP injection in mice 76
Beta-adrenergic receptor kinase: primary structure delineates a multigene family. 76
Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated Gaq. 75
Reduced insulin-induced phosphatidylinositol-3-kinase activation in peripheral blood mononuclear leucocytes from patients with Alzheimer's disease 75
The neurotoxicity of amphetamines: Bridging drugs of abuse and neurodegenerative disorders 75
Certain beta-blockers can decrease beta-adrenergic receptor number: I. Acute reduction in receptor number by tertatolol and bopindolol. 74
A liquid chromatography-tandem mass spectrometry method for the determination of 5-fluorouracil degradation rate by intact peripheral blood mononuclear cells 74
THE MAMMALIAN HOMOLOGUE OF THE NOVEL PEPTIDE Bv8 IS EXPRESSED IN THE CENTRAL NERVOUS SYSTEM AND SUPPORTS NEURONAL SURVIVAL BY ACTIVATING THE MAP KINASE/PI-3-KINASE PATHWAYS 73
P-SELECTIN INDUCES THE EXPRESSION OF TISSUE FACTOR ON MONOCYTES 72
Catecholamines do not induce fibrinolytic activity increase in cultured bovine endothelial cells. 71
Similarities between methamphetamine toxicity and proteasome inhibition 71
Beta-adrenergic receptor changes during tertatolol treatment in healthy volunteers: Relevance for beta-blocking therapy 70
Endogenous activation of group I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells 69
A pharmacokinetic and platelet function study of the combined administration of metoprolol and sulfinpyrazone to healthy volunteers 68
The G-protein coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1 68
Advances on beta-adrenergic receptors. Molecular structure and functional regulation. 66
Selective changes of receptor binding in brain regions of aged rats 66
Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. 65
Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism 65
GRK2 and beta-arrestin 1 as negative regulators of thyrotropin receptor-stimulated response. 65
Expression of OP4 (ORL1, NOP1) receptors in vascular endothelium 64
Expression of metabotropic glutamate receptors in the rat and human testis 63
Sulphinpyrazone increases lymphocyte beta-adrenoceptors in man. 63
Effects of chronic metoprolol and sulphinpyrazone on human lymphocyte beta-adrenoceptors. 63
Identification of a short sequence highly divergent between beta-adrenergic-receptor kinases 1 and 2 that determines the affinity of binding to beta gamma subunits of heterotrimeric guanine-nucleotide-binding regulatory proteins 63
Stress-Related Methylation of the Catechol-O-Methyltransferase Val(158) Allele Predicts Human Prefrontal Cognition and Activity 63
CALCULATING RECEPTOR NUMBER FROM BINDING EXPERIMENTS USING SAME COMPOUND AS RADIOLIGAND AND COMPETITOR 63
Differential regulation of membrane bound and soluble ICAM 1 in human endothelium and blood mononuclear cells: effects of interferon beta-1a 62
Molecular determinants of metabotropic glutamate receptor signaling 60
Involvement of G protein-coupled receptor kinases and arrestins in desensitization to follicle-stimulating hormone action. 60
Viral Infection for GPCR Expression in Eukaryotic Cells 59
Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins. 59
Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis 59
Reduction of beta-adrenergic receptors by tertatolol: an additional mechanism for beta-adrenergic blockade. 58
Role of 5-HT(2C) receptors in the control of central dopamine function. 58
Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity 57
Regulation of lysophosphatidic acid receptor-stimulated response by G-protein-coupled receptor kinase-2 and beta-arrestin1 in FRTL-5 rat thyroid cells 57
Receptor specificity of G-protein-coupled receptor kinases in target cells. 57
Regulation of G-protein-coupled receptor kinase subtypes by calcium sensor proteins. 56
Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor. 56
Molecular mechanisms that desensitize metabotropic glutamate receptor signaling: An overview 55
Reduction of beta-adrenergic receptors can explain the lack of rebound effect after tertatolol withdrawal. 53
Two isoforms of G protein-coupled receptor kinase 4 identified by molecular cloning 53
Selective reduction of one class of dopamine receptor binding sites in the corpus striatum of aged rats. 52
G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells. 52
Effects of m-chlorophenylpiperazine on receptor binding and brain metabolism of monoamines in rats. 51
Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets 51
Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells 51
Involvement of intramolecular interactions in the regulation of G protein-coupled receptor kinase 2 50
Regulation of Group II Metabotropic Glutamate Receptors by G Protein-Coupled Receptor Kinases: mGlu2 Receptors Are Resistant to Homologous Desensitization 50
Regulation of G protein-coupled receptor kinase subtypes in activated T lymphocytes. Selective increase of beta-adrenergic receptor kinase 1 and 2. 50
Metabotropic glutamate receptor subtypes as target for neuroprotetcive drugs 49
Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) 48
null 48
Peptide G protein-coupled receptors meet at Erice. 46
Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways 46
DESENSITIZATION AND REDISTRIBUTION OF BETA-ADRENERGIC RECEPTORS ON HUMAN MONONUCLEAR LEUKOCYTES 45
Drugs: guide and caveats to explanatory and descriptive approaches--II. Drugs in psychiatric research. 45
Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. 44
Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin. 44
In vivo regulation of beta-adrenergic receptors on human mononuclear leukocytes: assessment of receptor number, location, and function after posture change, exercise, and isoproterenol infusion. 44
Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. 42
Agonist-induced alpha 1-adrenergic receptor changes. Evidence for receptor sequestration. 41
Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing. 40
Changes in serotonin, but not catecholamine, receptor binding in the brain of morphine-dependent rats 39
Convergent roles of alpha-synuclein, DA metabolism, and the ubiquitin-proteasome system in nigrostriatal toxicity 39
The affinity of metergoline for 3H-Serotonin (5HT) binding sites is regulated by guanine nucleotide 38
Molecular cloning, functional expression and mRNA analysis of human beta-adrenergic receptor kinase 2. 38
Agonist-induced redistribution of beta-adrenergic receptors on intact human mononuclear leukocytes: redistributed receptors are nonfunctional. 38
Assignment of the beta-arrestin 1 gene (ARRB1) to human chromosome 11q13. 37
Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. 36
Presence of beta-arrestin in cellular inclusions in metamphetamine-treated PC12 cells. 36
Beta-adrenergic receptors: structure, function and regulation. 36
Selective regulation of G protein-coupled receptor-mediated signaling by G protein-coupled receptor kinase 2 in FRTL-5 cells: Analysis of thyrotropin, alpha(1B)-adrenergic, and A(1) adenosine receptor-mediated responses 35
Analysis of differential modulatory activities of GRK2 and GRK4 on G-alpha-q-coupled receptor signaling 35
The E27 ß2-adrenergic receptor polymorphism reduces the risk of myocardial infarction in dyslipidemic young males 35
Involvement of dopamine receptors and beta-arrestin in metamphetamine-induced inclusions formation in pc12 cells. 34
High plasma levels of catecholamines during insulin-induced hypoglycemic stress do not cause beta-adrenergic receptor sequestration. 34
An intact N terminus of the gamma subunit is required for the Gbetagamma stimulation of rhodopsin phosphorylation by human beta-adrenergic receptor kinase-1 but not for kinase binding. 34
Metabotropic glutamate receptor subtypes influence neuronal degeneration through different mechanisms 34
Rhodopsin phosphorylation by transiently expressed human beta ARK1: a new method for drug development. 34
Agonist-induced beta-adrenergic receptor internalization on intact human mononuclear leukocytes: effect of temperature of mononuclear leukocyte separation. 33
Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-Src modulates its interaction with Galphaq. 30
Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes. 27
Stress induced desensitization of lymphocyte beta-adrenoceptors in young and aged rats. 27
Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases. 27
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells. 26
Regulation of beta adrenergic receptors on rat mononuclear leukocytes by stress: receptor redistribution and down-regulation are altered with aging. 26
Two subpopulations of alpha 1-adrenergic receptors with high and low affinity for agonists: short-term exposure to agonists reduced the high-affinity sites. 25
Low affinity of beta-adrenergic receptors for agonists on intact cells is not due to receptor sequestration. 25
Totale 5.535
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Categoria #
all - tutte 16.765
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.765
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020829 0 0 0 0 0 145 166 159 150 89 89 31
2020/2021408 45 49 20 47 19 19 22 43 42 55 42 5
2021/20221.197 10 83 161 38 146 21 25 140 96 114 115 248
2022/20231.145 283 389 43 91 101 75 5 58 73 11 13 3
2023/2024320 31 58 14 16 28 12 1 13 0 52 29 66
2024/2025386 36 17 65 13 114 141 0 0 0 0 0 0
Totale 5.829