100 μM guanine nucleotide Gpp (NH)p reduces the affinity of the serotonergic antagonist metergoline for 3H-5HT binding sites in rat cerebral cortex. This effect is present both in inhibition binding and in saturation experiments. The hypothesis that the interaction of some serotonergic antagonists with 3H-5HT binding sites is regulated by guanine nucleotides is discussed. © 1983.
The affinity of metergoline for 3H-Serotonin (5HT) binding sites is regulated by guanine nucleotide / DE BLASI, Antonio; T., Mennini. - In: LIFE SCIENCES. - ISSN 0024-3205. - STAMPA. - 32:22(1983), pp. 2585-2588.
The affinity of metergoline for 3H-Serotonin (5HT) binding sites is regulated by guanine nucleotide
DE BLASI, ANTONIO;
1983
Abstract
100 μM guanine nucleotide Gpp (NH)p reduces the affinity of the serotonergic antagonist metergoline for 3H-5HT binding sites in rat cerebral cortex. This effect is present both in inhibition binding and in saturation experiments. The hypothesis that the interaction of some serotonergic antagonists with 3H-5HT binding sites is regulated by guanine nucleotides is discussed. © 1983.File allegati a questo prodotto
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