Catalogo dei prodotti della ricerca

POCE, Giovanna
 Distribuzione geografica
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Continente #
NA - Nord America 3.059
EU - Europa 901
AS - Asia 487
SA - Sud America 29
AF - Africa 14
Totale 4.490
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Nazione #
US - Stati Uniti d'America 3.006
IT - Italia 367
IN - India 199
CN - Cina 179
UA - Ucraina 128
FI - Finlandia 111
SE - Svezia 105
SG - Singapore 70
GB - Regno Unito 54
CA - Canada 45
DE - Germania 34
AR - Argentina 27
BG - Bulgaria 24
IE - Irlanda 22
RO - Romania 14
BE - Belgio 12
TW - Taiwan 12
ID - Indonesia 8
AT - Austria 7
IR - Iran 6
ZA - Sudafrica 6
MX - Messico 5
NL - Olanda 5
PL - Polonia 5
ME - Montenegro 4
TR - Turchia 4
BB - Barbados 3
FR - Francia 3
SY - Repubblica araba siriana 3
TG - Togo 3
BR - Brasile 2
DK - Danimarca 2
EG - Egitto 2
RU - Federazione Russa 2
SA - Arabia Saudita 2
SC - Seychelles 2
AL - Albania 1
CH - Svizzera 1
CI - Costa d'Avorio 1
JP - Giappone 1
KR - Corea 1
MY - Malesia 1
PK - Pakistan 1
Totale 4.490
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Città #
Fairfield 410
Chandler 288
Ashburn 265
Woodbridge 239
Houston 199
Rome 196
Seattle 174
Ann Arbor 165
Cambridge 151
Beijing 150
Wilmington 143
Princeton 91
Plano 77
New York 71
Boston 60
San Paolo di Civitate 48
Jacksonville 46
Lawrence 39
Helsinki 38
San Diego 35
Andover 28
Federal 27
Ottawa 26
Des Moines 25
Millbury 25
Sofia 24
Dublin 22
Boardman 20
Singapore 20
Norwalk 17
Toronto 17
Washington 17
Brussels 12
Pune 12
Taipei 12
Oxford 11
Naples 9
Florence 8
Milan 8
Falls Church 6
Hefei 6
Bühl 5
Fuzhou 5
Johannesburg 5
San Mateo 5
Vienna 5
Auburn Hills 4
Bozzolo 4
Dearborn 4
Hounslow 4
Trieste 4
Banda Aceh 3
Berlin 3
Bridgetown 3
Buffalo 3
Hyderabad 3
Lomé 3
Los Angeles 3
Magenta 3
Mentana 3
Nanjing 3
Pekanbaru 3
Southend 3
Velletri 3
Alexandria 2
Cassino 2
Civitavecchia 2
Codroipo 2
Crna Gora 2
Fasano 2
Frascati 2
Fremont 2
Henderson 2
Istanbul 2
Jinan 2
Karaj 2
Kochi 2
Kunming 2
León 2
Mexico City 2
Padova 2
Pessac 2
Pontianak 2
Porto Alegre 2
Randers 2
Redmond 2
Shenyang 2
Siena 2
Timisoara 2
Turin 2
Abidjan 1
Ancona 1
Arnsberg 1
Bern 1
Block 1
Brentford 1
Canosa di Puglia 1
Delhi 1
Escalaplano 1
Galdo 1
Totale 3.383
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Nome #
A novel antimycobacterial compound acts as an intracellular iron chelator 136
Activity of lipophilic and hydrophilic drugs against dormant and replicating mycobacterium tuberculosis 122
In vivo potent BM635 analogue with improved drug-like properties 98
Novel therapies for glaucoma: a patent review (2013-2019) 92
A series of COX-2 inhibitors endowed with NO-releasing properties: synthesis, biological evaluation, and docking analysis 91
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity 86
Mycobacterial tryptophan biosynthesis: a promising target for tuberculosis drug development? 86
1,5-Diarylpyrroles as potent antitubercular and anti-inflammatory agents 85
MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212 82
COX inhibitors: a patent review (2011 - 2014) 80
Developing Pyrrole-Derived Antimycobacterial Agents: a Rational Lead Optimization Approach 80
Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy 79
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 78
Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class 76
Novel pyrazole-containing compounds active against mycobacterium tuberculosis 73
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development 70
MmpL3 is the flippase for mycolic acids in mycobacteria 70
MmpL3 inhibitors: diverse chemical scaffolds inhibit the same target 70
C-9 Alkenylidine bridged macrolides: WO2008061189. 68
1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation 67
Novel Analgesic/Anti-Inflammatory Agents: Diarylpyrrole Acetic Esters Endowed with Nitric Oxide Releasing Properties 65
Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin 64
Enlarging the NSAIDs Family: Ether, Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Novel Anti-Inflammatory and Analgesic Agents 63
Sar analysis of small molecules interfering with energy-metabolism in mycobacterium tuberculosis 63
1,5-Diphenyl Pyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings 63
New 1,5-diarylpyrrole with improved antimycobacterial activity 62
New pyrroles with potential antimycobacterial, antifungal and COX-2 selective inhibiting activities. Synthetic methodologies 62
Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors 61
HPLC Enantioseparation and Absolute Configuration of Novel Antiinflammatory Pyrrole Derivatives 59
1,5-diarylpyrrole-3-acetic acids and esters as novel class of potent and selective COX-2 inhibitors. 59
Novel Analgesic/Anti-inflammatory Agents: 1,5-Diarylpyrrole Nitro-oxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors 59
New oxazolidinone derivatives as antibacterial agents with improved activity 58
Chocolate consumers and lymphocyte-to-monocyte ratio: a working hypothesis from a preliminary report of a pilot study in celiac subjects 57
Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme 57
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents 55
Direct-Acting Antivirals and Host-Targeting Approaches against Enterovirus B Infections: Recent Advances 54
Pyrrole Derivatives as New Antimycobacterial Class: Synthesis, S.A.R., Molecular Modelling Considerations and Microbiological Activity 54
The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and endothelial dysfunction 53
One-pot conversions of olefins to cyclic carbonates and secondary allylic and homoallylic amines to cyclic carbamates 52
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BM212 and its derivatives: lead optimization of a new class of antimycobacterial agents. 51
Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection 48
Cyclooxygenase-2 Inhibitors. 1,5-Diarylpyrrol-3-acetic Esters with Enhanced Inhibitory Activity toward Cyclooxygenase-2 and Improved Cyclooxygenase-2/Cyclooxygenase-1 Selectivity 48
Antimycobacterial agents. Novel diarylpirrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity 48
Malaria transmission blocking compounds: a patent review 48
Antiviral Mechanisms of N-Phenyl Benzamides on Coxsackie Virus A9 47
Doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure N-enoyl oxazolidin-2-ones: a mechanistic probe 47
New Pyrrole-based selective COX-2 inhibiting nitric oxide donors: synthesis, in vitro and in vivo evaluation 47
Identification of a new chemical class of potent antimycobacterial compounds derived from BM 212: design, synthesis, biological evaluation and study of their mode of action. 46
Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography 45
Nano-Based Drug Delivery Systems of Potent MmpL3 Inhibitors for Tuberculosis Treatment 44
A novel class of dual-acting DCH-CORMs counteracts oxidative stress-induced inflammation in human primary tenocytes 44
1,5-Diaryl-Pyrroles as New Generation of Anti-Inflammatory and Analgesic Agents: Design, Synthesis, in vitro and in vivo Evaluation 43
Potent in vitro and in vivo novel 1,5-Diarylpyrrole-3-acetic Esters COX-2 inhibitors. 42
Synthesis of new pyrrole derivatives of BM 212, a potent antimycobacterial compound 42
New derivatives of BM 212 with improved antimycobacterial activity. 42
6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis 40
Developing New Antiinflammatory and Analgesic Agents: Design, Synthesis, Biological and harmacological Evaluation 39
Therapeutic potential for coxibs-nitric oxide releasing hybrids in cystic fibrosis 39
Derivatives of BM 212: synthesis and biological evaluation of new derivatives with improved antimycobacterial activity. 38
New 1,5-diphenyl pyrrole derivatives as anti-inflammatory COX-2 selective compounds and their use as potential antitumoral agents. 36
Analogs of BM 212: a new chemical class of antimycobacterial agents acting upon a new target 33
BM212 targets MmpL3, Gordon Research Conference on Tuberculosis Drug Development 33
Overcoming drug resistance in TB: an update 33
1,5-DIARYLPYRROLE-3-ACETIC ACIDS AND ESTERS AS NOVEL CLASSES OF POTENT AND SELECTIVE COX-2 INHIBITORS. 31
1,5-Diphenyl pyrroles as new antimycobacterial agents. Hit-to-lead development and target validation, New drugs for neglected diseases 31
Stimuli-responsive tannin–feIII hybrid microcapsules demonstrated by the active release of an anti-tuberculosis agent 31
1,5-DIARYLPYRROLE DERIVATIVESAS NOVEL CLASSES OF ACTIVE AND SELECTIVE COX-2 INHIBITORS. 31
Design and synthesis of 1,5-diaryl-2-ethyl pyrrole derivatives and their evaluation as antimycobacterial agents 30
BM212 and new derivatives as a new class of antimycobacterial agents. 29
ENANTIOMERS OF NOVEL ANTIINFLAMMATORY PYRROLE DERIVATIVES:ANALYTICAL AND SEMIPREPARATIVE HPLC SEPARATION AND CHIROPTICAL PROPERTIES. 28
New 1,5 diarylpyrrole derivatives as antimycobacterial agents: Design, synthesis, biological evaluation and study of their mode of action 28
Design and Synthesis of novel diarylpyrroles as p38 MAP kinase inhibitors 28
Identification of a new Chemical Class of Potent Antimycobacterial Compounds 26
New pyrrole derivatives of BM 212: lead compound optimization strategy, Tuberculosis drug development. Targets, technologies and trials 26
Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-inflammatory and Analgesic Agents. Synthesis, in vitro and in vivo Biological Evaluation 26
New 1,5-diphenyl Pyrrole Derived from BM 212: a New class of Antimycobacterial Agents. 25
Pyrrole derivatives of BM212 as novel antimycobacterial agents Design, synthesis, biological evaluation and study of their mode of action 25
New 1,5-diphenyl pyrrole derived from BM 212: a new class of antimycobacterial Agents 25
Novel inhibitors of Mycobacterium tuberculosis tryptophan biosynthetic pathway to treat tuberculosis 25
Synthesis and biological evaluation of new heterocyclic derivatives with potential antimycobacterial activity: systematic approach to lead compound optimization 22
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New pyrrole derivatives of BM 212: a new class of antimycobacterial agents.Design, synthesis, biological evaluation and study of their mode of action. 21
Pyrrole-based selective COX-2 inhibiting nitric oxide donors: synthesis, in vitro and in vivo evaluation 21
New heterocyclic compounds with potential activity against parasitic protozoan: Trypanosoma and Leishmania 20
New Heterocyclic Compounds Targeting Trypanothyione Metabolism in Leishmania Parasites 17
Design, synthesis and screening of new antitubercular agents derived from BM 212 16
BM 579: a novel pyrrole derivative with improved antimycobacterial activity 16
New Pyrrole Derivatives as Anti-inflammatory and Analgesic Agents: Design, Synthesis and Biological Evaluation 15
Nuovi derivati 1,5-difenilpirrolici derivati del BM212 attivi come agenti antitubercolari 15
New pyrrole derivatives of BM 212: a new class of antimycobacterial agents. Design, synthesis, biological evaluation and study of their mode of action 15
Development of MmpL3 inhibitors for tuberculosis treatment 14
Pharmaceutical salt of BM635 with improved bioavailability 14
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors 13
Tannin microcapsules for synergy-enhanced sunscreen formulations 7
Overcoming drug resistance for tuberculosis, 6
Totale 4.633
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Categoria #
all - tutte 11.732
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.732
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019308 0 0 0 0 0 0 0 0 0 0 169 139
2019/2020991 137 44 16 39 73 100 107 117 99 149 77 33
2020/2021434 61 44 19 36 8 23 10 47 46 78 49 13
2021/2022832 10 54 81 32 117 19 20 74 84 70 83 188
2022/2023918 190 188 21 88 92 95 20 65 75 25 44 15
2023/2024607 37 84 43 49 62 173 26 59 9 52 13 0
Totale 4.633