PICCOLI, Mario
 Distribuzione geografica
Continente #
NA - Nord America 3.100
EU - Europa 1.026
AS - Asia 531
SA - Sud America 40
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.719
Nazione #
US - Stati Uniti d'America 3.050
IT - Italia 206
SG - Singapore 173
IN - India 172
UA - Ucraina 172
CN - Cina 166
SE - Svezia 163
FI - Finlandia 113
FR - Francia 80
NL - Olanda 79
DE - Germania 76
CA - Canada 46
GB - Regno Unito 43
AR - Argentina 37
BG - Bulgaria 21
TG - Togo 16
BE - Belgio 14
IE - Irlanda 14
AT - Austria 13
RO - Romania 9
IR - Iran 8
CH - Svizzera 6
GR - Grecia 5
TR - Turchia 5
RU - Federazione Russa 4
ZA - Sudafrica 3
BZ - Belize 2
CL - Cile 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
HK - Hong Kong 2
MX - Messico 2
PL - Polonia 2
AE - Emirati Arabi Uniti 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
KH - Cambogia 1
KR - Corea 1
KZ - Kazakistan 1
PE - Perù 1
PK - Pakistan 1
SC - Seychelles 1
VA - Santa Sede (Città del Vaticano) 1
Totale 4.719
Città #
Fairfield 415
Chandler 265
Woodbridge 261
Ashburn 226
Ann Arbor 211
Houston 175
Wilmington 142
Seattle 135
Cambridge 126
Singapore 114
Beijing 104
Princeton 100
Dearborn 90
Plano 87
San Paolo di Civitate 82
Paris 80
Fasano 73
Jacksonville 69
Lawrence 67
Boston 54
San Diego 43
Millbury 36
Federal 35
Rome 34
Ottawa 33
Andover 28
Boardman 28
Helsinki 26
Fremont 22
Sofia 21
Des Moines 18
Santa Clara 18
Lomé 16
Brussels 14
Dublin 14
Washington 14
Norwalk 13
Vienna 13
Toronto 11
New York 10
Bühl 9
Falls Church 9
Pune 9
Hefei 8
Nanjing 7
Buffalo 5
Falkenstein 5
Istanbul 5
Kunming 5
Mannheim 5
San Jose 5
Southend 5
Bern 4
Grafing 4
Laurel 4
Leawood 4
Zanjan 4
Dallas 3
Las Vegas 3
Milan 3
Muizenberg 3
Shanghai 3
Wenzhou 3
Acton 2
Albuquerque 2
Belize City 2
Buenos Aires 2
Chongqing 2
Hong Kong 2
Hounslow 2
Indiana 2
Jinan 2
Kilburn 2
Ladispoli 2
London 2
Mexico City 2
Nanchang 2
Prague 2
Provo 2
Redmond 2
Sacramento 2
San Francisco 2
Scafa 2
Tappahannock 2
Wuhan 2
Yellow Springs 2
Zurich 2
Almaty 1
Amsterdam 1
Athens 1
Auburn Hills 1
Berlin 1
Bremen 1
Cairo 1
Chicago 1
Dubai 1
Guangzhou 1
Hangzhou 1
Hebei 1
Henderson 1
Totale 3.499
Nome #
The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway 108
Hyperthermia enhances CD95-ligand gene expression in T lymphocytes 106
Adhesion and activation molecules expressed by human natural killer cells 99
Altered mucosal production of IL17A in pediatric celiac disease 96
Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell lysis 91
CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-beta1 90
Effects of protein kinase C (PK-C) activators and inhibitors on human large granular lymphocytes (LGL): role of PK-C on natural killer (NK) activity. 90
Size and dynamics of mucosal and peripheral IL-17A+ T-cell pools in pediatric age, and their disturbance in celiac disease 90
Candida albicans expresses a focal adhesion kinase-like protein that undergoes increased tyrosine phosphorylation upon yeast cell adhesion to vitronectin and the EA.hy 926 human endothelial cell line 83
CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: A new molecular mechanism to dampen mast cell function 80
Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine-activated killer cells with NK phenotype (LAK-NK) 79
Mechanisms involved in the activation and function of natural killer cells 77
Defective mucosal production of IL-17A in pediatric celiac disease 73
SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells 73
Src-dependent Syk activation controls CD69-mediated signaling and function on human NK cells 72
The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway. 72
Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration 72
Tyrosine kinase-dependent activation of human NK cell functions upon triggering through CD44 receptor 71
Signal transduction during NK cell activation via CD16: G proteins regulate inositol phosphate generation and ADCC activity 70
Triggering through CD16 or phorbol esters enhances adhesion of NK cells to laminin via very late antigen 6 70
Cloning of a novel human RNA polymerase II subunit downregulated by doxorubicin: new potential mechanisms of drug related toxicity 69
High-efficient lentiviral vector-mediated gene transfer into primary human NK cells 68
Inhibition of Nk-cell Generation By Corynebacterium Parvum 68
The adaptor protein shc is involved in the negative regulation of NK cell-mediated cytotoxicity. 67
CD44 triggering enhances human NK cell cytotoxic functions. 66
HUMAN NK CELLS EXPRESS ON CELL-SURFACE AN INTEGRIN STRUCTURE WHICH MEDIATE THEIR ADHESION TO FIBRONECTIN 66
Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma 66
Dynamics and amplitude of IL-17A-producing T cell populations in human gut mucosa and peripheral blood, and their disturbance in pediatric celiac disease 65
CD16-mediated p21ras activation is associated with SHC and p36 tyrosine phosphorylation and their association with Grb2 in human NK cells 64
PROLIFERATIVE EFFECTS OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE (TPA) AND CALCIUM IONOPHORES ON HUMAN LARGE GRANULAR LYMPHOCYTES (LGL) 64
Cutting edge: Functional role for proline-rich tyrosine kinase 2 in NK cell-mediated natural cytotoxicity 64
Augmentation of mouse natural killer (NK) activity by GM-1/P, a processed form of monosialoganglioside GM-1. 64
Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement 64
Expression of substance p and its neurokinin-1 receptor on thymocytes: functional relevance in the regulation of thymocyte apoptosis and proliferation. 63
Enhancement of lymphocyte proliferation and IL-2 receptor expression by a processed form (GM-1/P) of monosialoganglioside GM-1. 63
p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells 62
Regulation of mouse natural killer (NK) activity by interferon-γ (IFN-γ) 61
Negative regulation of CD95-ligand gene expression by vitamin D3 in T lymphocytes. 61
Distinct thymocyte subsets express the vanilloid receptor VR1 that mediates capsaicin-induced apoptotic cell death 60
A Laminin-like Protein Produced By Natural-killer (nk) Cells 59
CD94/NKG2-A inibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells. 58
PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway 58
Activation-dependent regulation of beta 1 integrin expression and function in human natural killer cells 58
15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors. 55
Modulation of CD16 antigen on NK cells and granulocytes by protein kinase C activators and inhibitors 55
IL-17A: a new inflammatory mediator in Coeliac Disease. 53
CD69-triggered ERK activation and functions are negatively regulated by CD94/NKG2A inhibitory receptor. 53
CHARACTERIZATION OF CORYNEBACTERIUM PARVUM-INDUCED SUPPRESSOR CELLS OF MOUSE NK AND ADCC ACTIVITY 52
Tyrosine kinase-dependent ubiquitination of CD16 zeta subunit in human NK cells following receptor engagement. 51
Beta 1 integrin cross-linking inhibits CD16-induced phospholipase D and secretory phospholipase A2 activity and granule exocytosis in human NK cells. Role of PLD in CD16-triggered degranulation 51
LAMININ SYNTHESIS BY NK CELLS AND MODULATION OF ITS EXPRESSION BY TPA (12-O-TETRADECANOYLPHORBOL-13-ACETATE) 51
RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells. 50
Locoregional IL-2 immunotherapy of bladder cancer 49
Regulation and function of fibronectin receptors expressed by natural killer cells 47
Coupling of beta 1 integrin to Ras-MAP kinase pathways controls IFN gamma mRNA expression in human NK cells 47
Candida albicans expresses a fibronectin receptor antigenically related to alpha 5 beta 1 integrin. 45
CD16-mediated activation of phosphatidylinositl-3 kinase (Pl-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 Pl-3K subunit. 44
Arf6: a new player in Fc gamma RIIIA lymphocyte-mediated cytotoxicity 43
Integrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells. 43
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. 43
Human natural killer cells express VLA-4 and VLA-5, which mediate their adhesion to fibronectin. 41
Local/regional recombinant interleukin 2 (rIL-2) immunotherapy of tumors. Intra-arterial continuous infusion of rIL-2 in bladder cancer patients: a phase I study. 39
Fibronectin receptors on NK cells 38
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 38
Cross-linking of Alpha-4-beta-1 and Alpha-5-beta-1 Fibronectin Receptors Enhances Natural-killer-cell Cytotoxic Activity 38
Granzyme A, una nuova proteasi granulo-associata, e' espressa in cellule NK fresche o attivate con interleuchina-2 37
CD16 engagement induces ubiquitination and degradation of Syk and ZAP-70 tyrosine kinases in human NK cells 37
Selective binding of shc-SH2 domain to tyrosine-phosphorylated zeta- but not gamma-chain upon CD16 ligation on human NK cells. 35
Proline-rich tyrosine kinase-2 activation by beta1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells. 35
Granzyme A expression by normal rat NK cells in vivo and by IL-2-activated NK cells in vitro 34
Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) in T lymphocytes 33
Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity 33
The cyclopentenone-type prostaglandin 15-deoxy-delta12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms 32
Changes in number and density of large granular lymphocytes upon in vivo augmentation of mouse natural killer activity 32
Overnight Incubation of Mouse Spleen-cells In Recombinant Il-2 Generates Cyto-toxic Cells With Nk Characteristics From Precursors Enriched With Or Devoid of Lgl 31
Ruolo delle proteine G nell’ attivazione delle cellule natural killer (NK) 30
Invitro Augmentation of Mouse Nk-cell Activity By Highly Purified Natural Interferon-gamma 29
Stimulation of protein tyrosine phosphorylation by interaction of NK cells with fibronectin via alpha 4 beta 1 and alpha 5 beta 1 28
Long term activation of natural killer cells results in modulation of beta 1-integrin expression and function. 28
Evidence for avb3 and avb5 integrin-like vitronectin (VN) receptors in Candida albicans and their involvement in Yeast cell adhesion to VN. 27
SEQUENTIAL METABOLIC EVENTS AND MORPHOLOGICAL-CHANGES DURING INVIVO LARGE ANTIGRANULOCYTES LYMPHOCYTE-ACTIVATION AND PROLIFERATION 27
Differential interaction of Shc-SH2 domain with Fc gamma RIII (CD16)-associated zeta and gamma chains 27
SERINE-ESTERASE GRANZYME-A EXPRESSION IN FRESH NK CELLS 25
Meccanismi biochimici di attivazione delle cellule natural killer (NK) 23
Triggers Deriving From CD44 Crosslinking Intervene In the Activation of Lytic Functions of Human Natural Killer Cells 23
Rat natural killer cells synthesize fibronectin. Possible involvement in the cytotoxic function. 21
Meccanismi implicati nello spegnimento delle vie di segnalazione mediate dal recettore ad alta affinità per le IgE (FcepsilonRI) 20
Totale 4.793
Categoria #
all - tutte 14.169
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 14.169


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020775 0 0 0 0 87 142 142 101 94 137 52 20
2020/2021488 64 39 12 27 11 35 81 44 27 44 26 78
2021/2022913 2 68 81 53 110 21 26 80 79 76 137 180
2022/20231.013 203 305 58 92 93 93 6 56 68 5 27 7
2023/2024369 19 57 20 28 49 80 3 23 1 44 22 23
2024/2025176 19 22 52 43 40 0 0 0 0 0 0 0
Totale 4.793