PERLUIGI, Marzia
 Distribuzione geografica
Continente #
NA - Nord America 10.259
AS - Asia 5.661
EU - Europa 3.516
SA - Sud America 927
AF - Africa 162
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 2
Totale 20.546
Nazione #
US - Stati Uniti d'America 10.056
SG - Singapore 2.365
IT - Italia 1.551
CN - Cina 898
VN - Vietnam 747
BR - Brasile 703
HK - Hong Kong 615
IN - India 458
DE - Germania 345
FI - Finlandia 308
FR - Francia 228
UA - Ucraina 202
SE - Svezia 189
RU - Federazione Russa 161
GB - Regno Unito 149
BD - Bangladesh 131
CA - Canada 116
AR - Argentina 107
IQ - Iraq 70
ID - Indonesia 68
NL - Olanda 66
JP - Giappone 59
ES - Italia 50
ZA - Sudafrica 47
IE - Irlanda 44
MX - Messico 41
AT - Austria 38
KR - Corea 36
PK - Pakistan 34
BE - Belgio 32
EC - Ecuador 31
TR - Turchia 29
TG - Togo 26
PL - Polonia 24
BG - Bulgaria 21
PH - Filippine 21
VE - Venezuela 21
SA - Arabia Saudita 20
AU - Australia 19
CL - Cile 19
CH - Svizzera 18
MA - Marocco 18
PT - Portogallo 17
CO - Colombia 16
RO - Romania 15
LT - Lituania 14
DZ - Algeria 11
EG - Egitto 11
KE - Kenya 11
PY - Paraguay 11
JO - Giordania 10
NP - Nepal 10
UZ - Uzbekistan 10
AZ - Azerbaigian 9
CZ - Repubblica Ceca 9
TT - Trinidad e Tobago 9
AE - Emirati Arabi Uniti 8
CR - Costa Rica 8
TN - Tunisia 8
UY - Uruguay 8
TH - Thailandia 7
AL - Albania 6
ET - Etiopia 6
AO - Angola 5
HN - Honduras 5
LB - Libano 5
MY - Malesia 5
NG - Nigeria 5
BO - Bolivia 4
IL - Israele 4
KZ - Kazakistan 4
PA - Panama 4
PE - Perù 4
QA - Qatar 4
SI - Slovenia 4
TW - Taiwan 4
BH - Bahrain 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HU - Ungheria 3
IR - Iran 3
JM - Giamaica 3
KG - Kirghizistan 3
LK - Sri Lanka 3
OM - Oman 3
PS - Palestinian Territory 3
SC - Seychelles 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BS - Bahamas 2
CI - Costa d'Avorio 2
DK - Danimarca 2
GL - Groenlandia 2
GT - Guatemala 2
GY - Guiana 2
HR - Croazia 2
KW - Kuwait 2
Totale 20.514
Città #
Fairfield 1.291
Ashburn 1.078
Singapore 1.046
Woodbridge 641
Rome 626
Hong Kong 579
San Jose 573
Houston 514
Chandler 507
Seattle 486
Cambridge 442
Ann Arbor 389
Wilmington 382
Beijing 275
Ho Chi Minh City 254
Dallas 243
Los Angeles 238
Princeton 171
Hanoi 162
New York 146
Fasano 145
San Paolo di Civitate 140
Buffalo 133
Munich 132
Helsinki 130
Plano 129
Lauterbourg 127
Lawrence 119
Santa Clara 110
The Dalles 98
Dearborn 96
Boston 92
Frankfurt am Main 92
Millbury 79
San Diego 74
Jacksonville 72
Hillsboro 71
Council Bluffs 68
São Paulo 66
Norwalk 50
Cosenza 45
Tokyo 45
Dublin 44
Turku 44
Redondo Beach 43
Toronto 43
Chicago 41
Federal 41
Haiphong 41
Milan 40
Boardman 39
Jakarta 39
Da Nang 38
Andover 37
Falkenstein 34
London 34
Moscow 33
Brussels 32
Montreal 30
Amsterdam 27
Baghdad 27
Orem 27
Hefei 26
Lomé 26
Naples 26
Guangzhou 25
Johannesburg 25
Des Moines 24
Nuremberg 24
Bengaluru 22
Brooklyn 22
Falls Church 22
Florence 21
Rio de Janeiro 21
Shanghai 21
Valencia 21
Lappeenranta 20
St Louis 20
Paris 19
Dhaka 18
Sofia 17
Chennai 16
Hải Dương 16
Istanbul 16
Phoenix 16
Palermo 15
Campinas 14
Denver 14
Mumbai 14
Porto Alegre 14
Warsaw 14
Coimbra 13
Grotteria 13
Kunming 13
Mannheim 13
Redwood City 13
Tianjin 13
Yubileyny 13
Atlanta 12
Belo Horizonte 12
Totale 13.574
Nome #
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype 248
Bach1 overexpression in down syndrome correlates with the alteration of the ho-1/bvr-a system: insights for transition to Alzheimer's disease 243
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome 236
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity 226
Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease 219
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome 206
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome 205
Redox control of viral carcinogenesis: the human papillomavirus paradigm 197
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β 196
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD 196
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity 192
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome 189
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease 184
The BACH1/Nrf2 axis in brain in down syndrome and transition to alzheimer disease-like neuropathology and dementia 178
Lack of p53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1, Biliverdin Reductase-A, Manganese Superoxide Dismutase, and Nuclear Factor Kappa-B 174
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles 171
It is all about (U)biquitin: role of altered ubiquitin-proteasome system and UCHL1 in Alzheimer disease 170
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease 170
Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm 170
Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways 165
4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies 165
An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. 163
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 161
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome 160
Antioxidants in cervical cancer: Chemopreventive and chemotherapeutic effects of polyphenols 156
HO-1/BVR-A system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: A potential biochemical marker for the prediction of the disease 156
Autoantibodies profile in matching CSF and serum from AD and aMCI patients: potential pathogenic role and link to oxidative damage 155
Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics 152
Oxidative Stress in HPV-Driven Viral Carcinogenesis: Redox Proteomics Analysis of HPV-16 Dysplastic and Neoplastic Tissues 152
The anti-diabetic drug metformin rescues aberrant mitochondrial activity and restrains oxidative stress in a female mouse model of rett syndrome 152
Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis 151
Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. 150
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: novel hints on immunosenescence and biomarker detection 150
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 149
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence 148
Metodi alternativi alla sperimentazione animale 147
Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism 147
Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study. 147
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease 146
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment 145
The dysregulation of OGT/OGA cycle mediates Tau and APP neuropathology in down syndrome 144
Proteomics strategies to analyze HPV-transformed cells: relevance to cervical cancer. 142
Cathepsin D as a therapeutic target in Alzheimer’s disease 142
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment 141
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome 141
Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain 140
Circulating biomarkers of protein oxidation for Alzheimer disease: Expectations within limits 139
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53 139
UVB irradiation down-regulates HPV-16 RNA expression: Implications for malignant progression of transformed cells 137
Neuropathological role of pi3k/akt/mtor axis in Down syndrome brain 137
Multiple Herpes simplex virus-1 (HSV-1) reactivations induce protein oxidative damage in mouse brain. Novel mechanisms for Alzheimer’s disease progression 137
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology 136
Poly-ubiquitin profile in Alzheimer disease brain 136
Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention 136
In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders. 135
Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro 134
Cytotoxicity of tetrahydroisoquinolines on melanoma cells 132
Redox Proteomics in Selected Neurodegenerative Disorders: From Its Infancy to Future Applications 132
Expression of human Papilloma virus type 16 E5 gene in amelanotic melanoma cells regulates endo-melanosomal pH and restores tyrosinase activity 128
MTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy 127
Targeting mitochondria in Alzheimer disease: rationale and perspectives 127
Redox proteomics and the dynamic molecular landscape of the aging brain. 126
Oxidative stress and down syndrome: A route toward Alzheimer-like dementia 126
Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target 126
Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion. 125
The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics 125
BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brain—Implications for neurodegeneration 125
Effects of uvb-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach. 123
Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study 123
In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress. 122
Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics. 122
Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain. 122
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models 122
I principi europei sui metodi alternativi alla sperimentazione animale 121
Oxidative stress, protein modification and Alzheimer disease 121
Microecology, bacterial vaginosis and probiotics: Perspectives for bacteriotherapy 121
Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid 121
Protein oxidative damage in UV-related skin cancer and dysplastic lesions contributes to neoplastic promotion and progression 120
Proteomics study of peripheral blood mononuclear cells in down syndrome children 120
Ectopic deposition of melanin pigments as detoxifying mechanism: a paradigm for basal nuclei pigmentation 120
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome 120
Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells 119
Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics 118
Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain. 118
Introductory editorial: drug-eluting stents or drug-eluting grafts? insights from proteomic analysis 118
Metformin treatment rescues aberrant mitochondrial activity and oxidative stress status in the brain of female mouse model of Rett syndrome 118
Serum proteomics in patients with diagnosis of abdominal aortic aneurysm 117
Cell Cycle Proteins in Brain in Mild Cognitive Impairment: Insights into Progression to Alzheimer Disease. 117
Redox proteomics in human biofluids: sample preparation, separation and immunochemical tagging for analysis of protein oxidation 117
Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer’s Disease and Amnestic Mild Cognitive Impairment 117
Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease 116
Redox Proteomics Analyses of the Influence of Co-Expression of Wild-Type or Mutated LRRK2 and Tau on C. elegans Protein Expression and Oxidative Modification: Relevance to Parkinson Disease 116
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease 114
Potential therapeutic value of the anti-diabetic drug metformin in a mouse model of Rett syndrome: a preclinical study 114
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: Redox proteomics analysis of human brain 114
NF-κB-mediated cytokine secretion and glutamate metabolic reprogramming converge in breast cancer brain tropism 113
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis 113
Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula 113
Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. 111
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. 111
Totale 14.494
Categoria #
all - tutte 58.420
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 339
other - altro 0
patent - brevetti 157
selected - selezionate 0
volume - volumi 0
Totale 58.916


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021145 0 0 0 0 0 0 0 0 0 0 110 35
2021/20221.826 174 118 186 25 172 61 66 172 108 124 325 295
2022/20231.724 301 397 80 222 168 148 53 97 137 22 79 20
2023/2024959 73 108 45 68 111 201 17 36 5 99 99 97
2024/20253.627 81 179 160 157 127 217 228 362 654 313 240 909
2025/20267.405 703 477 702 706 994 386 1.048 380 584 933 492 0
Totale 21.115