PERLUIGI, Marzia
 Distribuzione geografica
Continente #
NA - Nord America 12.653
AS - Asia 5.899
EU - Europa 4.756
SA - Sud America 961
Continente sconosciuto - Info sul continente non disponibili 581
AF - Africa 166
OC - Oceania 19
Totale 25.035
Nazione #
US - Stati Uniti d'America 12.322
IT - Italia 2.754
SG - Singapore 2.382
CN - Cina 932
VN - Vietnam 749
BR - Brasile 724
HK - Hong Kong 622
IN - India 465
DE - Germania 348
FI - Finlandia 308
BD - Bangladesh 294
FR - Francia 234
UA - Ucraina 202
SE - Svezia 189
CA - Canada 174
GB - Regno Unito 166
RU - Federazione Russa 161
AR - Argentina 107
IQ - Iraq 70
NL - Olanda 70
ID - Indonesia 68
JP - Giappone 60
ES - Italia 51
ZA - Sudafrica 48
IE - Irlanda 44
MX - Messico 44
AT - Austria 39
KR - Corea 36
EC - Ecuador 34
PK - Pakistan 34
BE - Belgio 32
TR - Turchia 31
TG - Togo 27
VE - Venezuela 25
PL - Polonia 24
CR - Costa Rica 23
PH - Filippine 22
BG - Bulgaria 21
CL - Cile 21
JM - Giamaica 20
SA - Arabia Saudita 20
AU - Australia 19
CH - Svizzera 18
CO - Colombia 18
MA - Marocco 18
PT - Portogallo 17
RO - Romania 15
LT - Lituania 14
TT - Trinidad e Tobago 14
PY - Paraguay 12
DZ - Algeria 11
EG - Egitto 11
KE - Kenya 11
JO - Giordania 10
NP - Nepal 10
UZ - Uzbekistan 10
AE - Emirati Arabi Uniti 9
AZ - Azerbaigian 9
CZ - Repubblica Ceca 9
TN - Tunisia 8
UY - Uruguay 8
AL - Albania 7
GT - Guatemala 7
HN - Honduras 7
MY - Malesia 7
NI - Nicaragua 7
TH - Thailandia 7
ET - Etiopia 6
AO - Angola 5
BB - Barbados 5
IL - Israele 5
LB - Libano 5
NG - Nigeria 5
PE - Perù 5
SC - Seychelles 5
BO - Bolivia 4
KZ - Kazakistan 4
PA - Panama 4
PR - Porto Rico 4
QA - Qatar 4
SI - Slovenia 4
SV - El Salvador 4
TW - Taiwan 4
BH - Bahrain 3
BY - Bielorussia 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HR - Croazia 3
HU - Ungheria 3
IR - Iran 3
KG - Kirghizistan 3
LK - Sri Lanka 3
OM - Oman 3
PS - Palestinian Territory 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
AG - Antigua e Barbuda 2
BA - Bosnia-Erzegovina 2
BS - Bahamas 2
Totale 24.411
Città #
Ashburn 1.291
Fairfield 1.291
Singapore 1.058
Rome 866
San Jose 752
Woodbridge 641
Milan 601
Hong Kong 584
Houston 523
Chandler 507
Seattle 490
Cambridge 442
Dallas 401
Ann Arbor 389
Wilmington 386
Beijing 302
Los Angeles 284
Ho Chi Minh City 256
Council Bluffs 212
New York 193
Princeton 173
Santa Clara 166
Hanoi 162
Buffalo 161
Fasano 145
San Paolo di Civitate 140
Figino 135
Munich 132
Helsinki 130
Plano 129
Lauterbourg 127
Lawrence 120
The Dalles 103
Boston 100
Dearborn 96
Frankfurt am Main 95
Jacksonville 80
Millbury 79
San Diego 75
São Paulo 73
Hillsboro 71
Phoenix 62
Chicago 54
Toronto 52
Norwalk 50
Tokyo 46
Cosenza 45
Dublin 44
Turku 44
Boardman 43
London 43
Redondo Beach 43
Federal 41
Haiphong 41
Montreal 41
Jakarta 39
Da Nang 38
Andover 37
Naples 35
Falkenstein 34
Denver 33
Florence 33
Moscow 33
Brussels 32
Orem 31
Atlanta 29
Amsterdam 28
Baghdad 27
Brooklyn 27
Lomé 27
St Louis 27
Hefei 26
Johannesburg 26
Guangzhou 25
Des Moines 24
Nuremberg 24
Bologna 23
Bengaluru 22
Falls Church 22
Rio de Janeiro 22
Shanghai 21
Valencia 21
Lappeenranta 20
Mumbai 19
Paris 19
Piscataway 19
Dhaka 18
Palermo 18
San Francisco 17
Sofia 17
Turin 17
Chennai 16
Hải Dương 16
Istanbul 16
Bari 15
Miano 15
San José 15
Campinas 14
Miami 14
Porto Alegre 14
Totale 15.675
Nome #
Circulating biomarkers of protein oxidation for Alzheimer disease: Expectations within limits 310
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype 308
Proteomics study of peripheral blood mononuclear cells in down syndrome children 300
Ectopic deposition of melanin pigments as detoxifying mechanism: a paradigm for basal nuclei pigmentation 298
Bach1 overexpression in down syndrome correlates with the alteration of the ho-1/bvr-a system: insights for transition to Alzheimer's disease 295
Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes 280
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome 273
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity 245
Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease 240
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome 233
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome 228
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity 218
Redox control of viral carcinogenesis: the human papillomavirus paradigm 216
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD 215
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β 214
Lack of p53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1, Biliverdin Reductase-A, Manganese Superoxide Dismutase, and Nuclear Factor Kappa-B 209
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome 200
The BACH1/Nrf2 axis in brain in down syndrome and transition to alzheimer disease-like neuropathology and dementia 198
Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm 194
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles 193
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease 191
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease 191
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome 191
4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies 186
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 183
An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. 182
Oxidative Stress in HPV-Driven Viral Carcinogenesis: Redox Proteomics Analysis of HPV-16 Dysplastic and Neoplastic Tissues 179
It is all about (U)biquitin: role of altered ubiquitin-proteasome system and UCHL1 in Alzheimer disease 177
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence 177
Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis 176
Antioxidants in cervical cancer: Chemopreventive and chemotherapeutic effects of polyphenols 175
NF-κB-mediated cytokine secretion and glutamate metabolic reprogramming converge in breast cancer brain tropism 174
Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways 173
Multiple Herpes simplex virus-1 (HSV-1) reactivations induce protein oxidative damage in mouse brain. Novel mechanisms for Alzheimer’s disease progression 170
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment 169
Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. 169
Autoantibodies profile in matching CSF and serum from AD and aMCI patients: potential pathogenic role and link to oxidative damage 169
Neuropathological role of pi3k/akt/mtor axis in Down syndrome brain 168
Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics 168
Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study. 167
HO-1/BVR-A system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: A potential biochemical marker for the prediction of the disease 166
Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention 166
Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism 165
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome 165
Proteomics strategies to analyze HPV-transformed cells: relevance to cervical cancer. 164
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 164
In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders. 162
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease 162
Cathepsin D as a therapeutic target in Alzheimer’s disease 161
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment 160
The anti-diabetic drug metformin rescues aberrant mitochondrial activity and restrains oxidative stress in a female mouse model of rett syndrome 160
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology 159
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53 158
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: novel hints on immunosenescence and biomarker detection 158
Metodi alternativi alla sperimentazione animale 156
Poly-ubiquitin profile in Alzheimer disease brain 156
Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro 155
The dysregulation of OGT/OGA cycle mediates Tau and APP neuropathology in down syndrome 155
Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain 154
Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain. 154
MTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy 152
Expression of human Papilloma virus type 16 E5 gene in amelanotic melanoma cells regulates endo-melanosomal pH and restores tyrosinase activity 150
UVB irradiation down-regulates HPV-16 RNA expression: Implications for malignant progression of transformed cells 150
Redox proteomics and the dynamic molecular landscape of the aging brain. 150
Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study 148
Targeting mitochondria in Alzheimer disease: rationale and perspectives 147
BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brain—Implications for neurodegeneration 146
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models 145
Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target 145
Redox Proteomics in Selected Neurodegenerative Disorders: From Its Infancy to Future Applications 144
The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics 143
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome 143
Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease 142
Cytotoxicity of tetrahydroisoquinolines on melanoma cells 141
Protein oxidative damage in UV-related skin cancer and dysplastic lesions contributes to neoplastic promotion and progression 141
Oxidative stress, protein modification and Alzheimer disease 140
Behavioural and neuropathological effects of intranasal insulin treatment in a triple-transgenic mouse model of Alzheimer's disease (3xTg-AD) 140
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: Redox proteomics analysis of human brain 140
Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer’s Disease and Amnestic Mild Cognitive Impairment 140
Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics 139
mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia 139
Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis 138
Redox Proteomics Analyses of the Influence of Co-Expression of Wild-Type or Mutated LRRK2 and Tau on C. elegans Protein Expression and Oxidative Modification: Relevance to Parkinson Disease 138
Serum proteomics in patients with diagnosis of abdominal aortic aneurysm 138
In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress. 137
Oxidative stress and down syndrome: A route toward Alzheimer-like dementia 135
Down syndrome Is a metabolic disease: altered Insulin signaling mediates peripheral and brain dysfunctions 135
Redox proteomics in human biofluids: sample preparation, separation and immunochemical tagging for analysis of protein oxidation 134
Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells 134
Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid 134
Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. 133
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis 132
Effects of uvb-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach. 132
Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics. 132
Microecology, bacterial vaginosis and probiotics: Perspectives for bacteriotherapy 132
Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion. 131
Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain. 131
Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula 131
HNE-modified proteins in Down syndrome: involvement in development of Alzheimer disease neuropathology 131
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease 130
Totale 17.165
Categoria #
all - tutte 68.395
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 382
other - altro 0
patent - brevetti 196
selected - selezionate 0
volume - volumi 0
Totale 68.973


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.348 0 0 0 25 172 61 66 172 108 124 325 295
2022/20231.724 301 397 80 222 168 148 53 97 137 22 79 20
2023/2024959 73 108 45 68 111 201 17 36 5 99 99 97
2024/20253.627 81 179 160 157 127 217 228 362 654 313 240 909
2025/20268.130 703 477 702 706 994 386 1.048 380 584 933 676 541
2026/20273.195 588 1.500 1.096 11 0 0 0 0 0 0 0 0
Totale 25.035