| Nome |
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Should ACE2 be given a chance in COVID-19 therapeutics: a semi-systematic review of strategies enhancing ACE2, file e3835328-6263-15e8-e053-a505fe0a3de9
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318
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Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes, file e383532e-0b03-15e8-e053-a505fe0a3de9
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276
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Oxidative stress: a key modulator in neurodegenerative diseases, file e3835322-b022-15e8-e053-a505fe0a3de9
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275
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Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress, file e383532a-d2eb-15e8-e053-a505fe0a3de9
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266
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The NRF2/KEAP1 axis in the regulation of tumor metabolism: mechanisms and therapeutic perspectives, file e3835328-518a-15e8-e053-a505fe0a3de9
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257
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9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2, file e383531a-2104-15e8-e053-a505fe0a3de9
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220
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Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents, file e3835321-73df-15e8-e053-a505fe0a3de9
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218
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Renoprotective effect of tectorigenin glycosides isolated from Iris spuria L. (Zeal) against hyperoxaluria and hyperglycemia in NRK-49Fcells, file e3835328-5866-15e8-e053-a505fe0a3de9
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180
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Natural sources, pharmacokinetics, biological activities and health benefits of hydroxycinnamic acids and their metabolites, file e3835328-53f2-15e8-e053-a505fe0a3de9
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177
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Potential applications of NRF2 inhibitors in cancer therapy, file e3835322-d3a6-15e8-e053-a505fe0a3de9
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168
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Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling, file e383531a-99e6-15e8-e053-a505fe0a3de9
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147
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Role of c-MET inhibitors in overcoming drug resistance in spheroid models of primary human pancreatic cancer and stellate cells, file e3835322-d3a2-15e8-e053-a505fe0a3de9
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141
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Antioxidant activity of synthetic polymers of phenolic compounds, file e3835328-518c-15e8-e053-a505fe0a3de9
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139
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Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations, file e3835328-92eb-15e8-e053-a505fe0a3de9
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134
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Protective effects of flavonoids against mitochondriopathies and associated pathologies: focus on the predictive approach and personalized prevention, file e383532c-afb1-15e8-e053-a505fe0a3de9
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133
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Redox control of multidrug resistance and Its possible modulation by antioxidants, file e3835315-ff8f-15e8-e053-a505fe0a3de9
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117
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Ellagic Acid-Derived Urolithins as Modulators of Oxidative Stress, file e3835328-53f4-15e8-e053-a505fe0a3de9
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116
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Screening pyridine derivatives against human hydrogen sulfide-synthesizing enzymes by orthogonal methods, file e3835325-8c72-15e8-e053-a505fe0a3de9
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110
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Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds, file e383531a-5535-15e8-e053-a505fe0a3de9
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106
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Controversy about pharmacological modulation of Nrf2 for cancer therapy, file e383531a-5cef-15e8-e053-a505fe0a3de9
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106
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Systems approach to identify common genes and pathways associated with response to selective serotonin reuptake inhibitors and major depression risk, file e3835322-b026-15e8-e053-a505fe0a3de9
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106
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Lanthanide(III) complexes are more active inhibitors of the Fenton reaction than pure ligands, file e3835315-c81a-15e8-e053-a505fe0a3de9
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105
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Ribosome-directed therapies in cancer, file 678e5813-7754-4a83-bb47-c66a974b8101
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104
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Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique, file e383531a-3f5a-15e8-e053-a505fe0a3de9
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104
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The simple isocratic HPLC-UV method for the simultaneous determination of reduced and oxidized glutathione in animal tissue, file e383531a-232f-15e8-e053-a505fe0a3de9
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103
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Disulfiram moderately restores impaired hepatic redox status of rats subchronically exposed to cadmium, file e3835321-8037-15e8-e053-a505fe0a3de9
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103
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Neuroprotective and antioxidant activities of 4-methylcoumarins: development of structure-activity relationships, file e3835316-1c85-15e8-e053-a505fe0a3de9
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102
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Effect of oxidative stress on ABC transporters: contribution to epilepsy pharmacoresistance, file e383531a-7f5a-15e8-e053-a505fe0a3de9
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102
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Targeting ferroptosis against ischemia/reperfusion cardiac injury, file e383532c-0fff-15e8-e053-a505fe0a3de9
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102
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Global text mining and development of pharmacogenomic knowledge resource for precision medicine, file e3835328-8171-15e8-e053-a505fe0a3de9
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101
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Probable reasons for neuron copper deficiency in the brain of patients with Alzheimer’s disease: the complex role of amyloid, file e383532e-0b05-15e8-e053-a505fe0a3de9
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101
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Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress, file e3835314-b6ae-15e8-e053-a505fe0a3de9
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98
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Behaviour of 9-Ethyl-9H-carbazole hydrazone derivatives against oxidant systems: protective effect on amyloid β-induced damage, file e3835322-d394-15e8-e053-a505fe0a3de9
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96
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Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study, file e383531a-4de6-15e8-e053-a505fe0a3de9
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91
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Pharmacological applications of Nrf2 inhibitors as potential antineoplastic drugs, file e3835322-d39a-15e8-e053-a505fe0a3de9
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88
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Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease, file e383531a-5cf0-15e8-e053-a505fe0a3de9
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86
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Relation of redox and structural alterations of rat skin in the function of chronological aging, file e3835322-b02c-15e8-e053-a505fe0a3de9
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86
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Synthesis and characterization of 3-(1-((3,4-dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a potential antitumor agent, file e3835322-d3a4-15e8-e053-a505fe0a3de9
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85
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In vitro assessment of the effect of antiepileptic drugs on expression and function of ABC transporters and their interactions with ABCC2, file e383531a-5acf-15e8-e053-a505fe0a3de9
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83
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HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers, file e3835328-5869-15e8-e053-a505fe0a3de9
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83
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Cardiovascular mitochondrial dysfunction induced by cocaine: biomarkers and possible beneficial effects of modulators of oxidative stress, file e3835316-f81a-15e8-e053-a505fe0a3de9
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81
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The role of toxic metals and metalloids in nrf2 signaling, file e383532c-06f6-15e8-e053-a505fe0a3de9
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81
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PFAS molecules: a major concern for the human health and the environment, file e383532e-4cdd-15e8-e053-a505fe0a3de9
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80
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Regulation of the Nrf2 pathway by glycogen synthase kinase-3β in MPP+-induced cell damage, file e3835322-d39e-15e8-e053-a505fe0a3de9
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78
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An overview of NRF2-activating compounds bearing α,β-unsaturated moiety and their antioxidant effects, file c65571a3-f9e1-4534-8d53-6b253367fa67
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75
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Antioxidant activity and protective role on protein glycation of synthetic aminocoumarins, file e383531a-172f-15e8-e053-a505fe0a3de9
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73
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Pharmacological protection against ischemia-reperfusion injury by regulating the nrf2-keap1-are signaling pathway, file e383532b-fbf3-15e8-e053-a505fe0a3de9
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72
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Alkaloids and colon cancer: molecular mechanisms and therapeutic implications for cell cycle arrest, file e383532e-0aff-15e8-e053-a505fe0a3de9
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71
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An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation, file e3835328-7227-15e8-e053-a505fe0a3de9
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69
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Nutrition strategy and life style in polycystic ovary syndrome—narrative review, file e383532c-a797-15e8-e053-a505fe0a3de9
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68
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Modulation of oxidative stress: pharmaceutical and pharmacological aspects, file e3835321-63e3-15e8-e053-a505fe0a3de9
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66
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Regulatory role of Nrf2 signaling pathway in wound healing process, file e383532b-dfb2-15e8-e053-a505fe0a3de9
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64
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Genetic landscape of common epilepsies: advancing towards precision in treatment, file e3835328-6b5f-15e8-e053-a505fe0a3de9
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61
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Nanotechnology-based drug delivery to improve the therapeutic benefits of NRF2 modulators in cancer therapy, file e383532c-06f9-15e8-e053-a505fe0a3de9
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60
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Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis, file e3835328-517f-15e8-e053-a505fe0a3de9
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59
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Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System, file e3835328-c8aa-15e8-e053-a505fe0a3de9
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59
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Nitro-oxidative stress and mitochondrial dysfunction in human cell lines exposed to the environmental contaminants PFOA and BPA, file 9aad4c40-1b0d-45fc-9c54-17551c1b112a
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56
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The unity of redox and structural remodeling of brown adipose tissue in hypothyroidism, file e383532c-b29c-15e8-e053-a505fe0a3de9
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54
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Human genetic factors associated with pneumonia risk, a cue for COVID-19 susceptibility, file e383532e-fd0a-15e8-e053-a505fe0a3de9
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54
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Modulation of neurotrophic signaling pathways by polyphenols, file e3835315-fc52-15e8-e053-a505fe0a3de9
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53
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Downregulation of peripheral PTGS2/COX-2 in response to valproate treatment in patients with epilepsy, file e3835328-53ef-15e8-e053-a505fe0a3de9
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53
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Multivariate analysis of polyphenolic content and in vitro antioxidant capacity of wild and cultivated berries from Bosnia and Herzegovina, file e383532c-ff24-15e8-e053-a505fe0a3de9
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53
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Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in alzheimer’s disease and parkinson’s disease, file e3835328-cdf2-15e8-e053-a505fe0a3de9
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52
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Oxidative stress in amyotrophic lateral sclerosis: pathophysiology and opportunities for pharmacological intervention, file e3835328-65fb-15e8-e053-a505fe0a3de9
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51
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Potential applications of NRF2 modulators in cancer therapy, file e3835328-5192-15e8-e053-a505fe0a3de9
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50
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Modulation of oxidative stress: pharmaceutical and pharmacological aspects 2018, file e3835328-586d-15e8-e053-a505fe0a3de9
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50
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Insight into the biological activity of hennosides—glucosides isolated from Lawsonia inermis (henna). Could they be regarded as active constituents instead, file e3835329-97d5-15e8-e053-a505fe0a3de9
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50
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Kaempferol as a dietary anti-inflammatory agent: current therapeutic standing, file e3835328-6260-15e8-e053-a505fe0a3de9
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49
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Anti-Viral Potential and Modulation of Nrf2 by Curcumin: Pharmacological Implications, file e3835328-7f12-15e8-e053-a505fe0a3de9
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49
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In vitro interaction of 5‐aminoorotic acid and its gallium(III) complex with superoxide radical, generated by two model systems, file e3835328-5126-15e8-e053-a505fe0a3de9
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46
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Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach, file e3835328-7fd7-15e8-e053-a505fe0a3de9
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46
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Prior activation of 5-HT7 receptors modulates the conditioned place preference with methylphenidate, file e3835328-b589-15e8-e053-a505fe0a3de9
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46
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The role of prokineticin 2 in oxidative stress and in neuropathological processes, file e383532a-acf4-15e8-e053-a505fe0a3de9
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45
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Potential antioxidant multitherapy against complications occurring in sepsis, file 873cc683-b2e1-4db5-95a8-d0c441b9dda8
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44
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Modulators of oxidative stress: chemical and pharmacological aspects, file e3835328-53eb-15e8-e053-a505fe0a3de9
|
44
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|
Imidazopyridine hydrazone derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c-Met, file e3835329-9ab9-15e8-e053-a505fe0a3de9
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44
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Flavonoids targeting HIF-1: implications on cancer metabolism, file e3835328-e7ef-15e8-e053-a505fe0a3de9
|
43
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|
Diverse and complex challenges to migrant and refugee rental health: reflections of the M8 alliance expert group on migrant health, file e3835328-80a3-15e8-e053-a505fe0a3de9
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42
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Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's Disease, file e383532f-2e37-15e8-e053-a505fe0a3de9
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42
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|
Neuropeptide Y promotes human M2 macrophage polarization and enhances p62/SQSTM1-dependent autophagy and NRF2 activation, file 4a474eeb-8438-4539-9cb6-d7248c1ef4fa
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41
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|
Synthesis, in vitro antioxidant properties and distribution of a new cyanothiophene-based phenolic compound in olive oil-in-water emulsions, file e3835328-625c-15e8-e053-a505fe0a3de9
|
41
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|
Critical reflections, challenges and solutions for migrant and refugee health: 2nd M8 Alliance Expert Meeting, file e3835328-80a9-15e8-e053-a505fe0a3de9
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41
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5-Oxo-hexahydroquinoline derivatives and their tetrahydroquinoline counterparts as multidrug resistance reversal agents, file e3835328-625e-15e8-e053-a505fe0a3de9
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40
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|
Evaluation of the radical scavenging activity of some representative isoprenoid and aromatic cytokinin ribosides (N6-substituted adenosines) by in vitro chemical assays, file e383532e-382f-15e8-e053-a505fe0a3de9
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39
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|
Natural chain-breaking antioxidants and their synthetic analogs as modulators of oxidative stress, file e383532b-e3f5-15e8-e053-a505fe0a3de9
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38
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|
Involvement of NRF2 in breast cancer and possible therapeutical role of polyphenols and melatonin, file e383532b-0d1d-15e8-e053-a505fe0a3de9
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37
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Alkaloids as natural NRF2 inhibitors: chemoprevention and cytotoxic action in cancer, file bacd4b5e-afc1-4ed9-b317-1f57db1ac93e
|
36
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|
Antioxidant activities of alkyl substituted pyrazine derivatives of chalcones-in vitro and in silico study, file e3835328-80ab-15e8-e053-a505fe0a3de9
|
36
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|
Synthesis, Crystallographic, Quantum Chemical, Antitumor, and Molecular Docking/Dynamic Studies of 4-Hydroxycoumarin-Neurotransmitter Derivatives, file e383532e-39b9-15e8-e053-a505fe0a3de9
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36
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The effects of trifluoromethylated derivatives on prostaglandin E2 and thromboxane A2 production in human leukemic U937 macrophages, file e3835326-d22b-15e8-e053-a505fe0a3de9
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35
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|
Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders, file e383532d-c835-15e8-e053-a505fe0a3de9
|
35
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Cardioprotective mechanisms against reperfusion injury in acute myocardial infarction: targeting angiotensin II receptors, file a0c0fb04-3579-488b-8487-658f9dc58123
|
33
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|
NRF2: A crucial regulator for mitochondrial metabolic shift and prostate cancer progression, file fb0f04e0-0c28-4fce-9d11-4ed2903a16dc
|
32
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Therapeutic targeting of the NRF2 signaling pathway in cancer, file e383532b-28eb-15e8-e053-a505fe0a3de9
|
31
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|
Antifungal and Cytotoxic Activity of Diterpenes and Bisnorsesquiterpenoides from the Latex of Euphorbia resinifera Berg, file 623d14c0-4917-49a3-b0af-2c0c391188ca
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30
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Oxidative stress in mucopolysaccharidoses: pharmacological implications, file e383532c-adbb-15e8-e053-a505fe0a3de9
|
27
|
|
Astaxanthin as a modulator of Nrf2, NF-κB, and their crosstalk: molecular mechanisms and possible clinical applications, file e383532e-04c1-15e8-e053-a505fe0a3de9
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27
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|
Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and Therapeutic Potential, file e383532e-b7f5-15e8-e053-a505fe0a3de9
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21
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Ascorbate as a bioactive compound in cancer therapy: the old classic strikes back, file e383532f-4430-15e8-e053-a505fe0a3de9
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19
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|
Antioxidant intervention against male infertility: time to design novel strategies, file 170e6214-eaeb-4565-8ffd-58d3ad491d65
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17
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| Totale |
8.458 |