The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes.

Motivation: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. © 2013 The Author 2013. Published by Oxford University Press. All rights reserved.

TiPs: A database of therapeutic targets in pathogens and associated tools / Lepore, Rosalba; Tramontano, Anna; Via, Allegra. - In: BIOINFORMATICS. - ISSN 1367-4803. - STAMPA. - 29:14(2013), pp. 1821-1822. [10.1093/bioinformatics/btt289]

TiPs: A database of therapeutic targets in pathogens and associated tools

LEPORE, ROSALBA;TRAMONTANO, ANNA;VIA, ALLEGRA
2013

Abstract

The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes.
2013
Motivation: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. © 2013 The Author 2013. Published by Oxford University Press. All rights reserved.
target discovery; human pathogens; database
01 Pubblicazione su rivista::01a Articolo in rivista
TiPs: A database of therapeutic targets in pathogens and associated tools / Lepore, Rosalba; Tramontano, Anna; Via, Allegra. - In: BIOINFORMATICS. - ISSN 1367-4803. - STAMPA. - 29:14(2013), pp. 1821-1822. [10.1093/bioinformatics/btt289]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/541232
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 2
social impact