Although peritoneal carcinomatosis from breast cancer is a rare event it frequently causes morbidity and mortality. Current literature provides scarce information on its management. We report outcomes in 5 patients (mean age 59.4 years) with peritoneal carcinomatosis from breast cancer treated with maximal cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) by the closed technique, at 40 °C for 1 h with cisplatin 75 mg/m(2). The primary breast cancer was a ductal carcinoma in 3 patients and a lobular carcinoma in 2. Mean peritoneal cancer index was 20.2. In 4 of the 5 patients surgery achieved macroscopic complete cytoreduction. One patient died of disease at 56 months, 4 are alive and disease-free at 13, 45, 74 and 128 months. These encouraging outcomes suggest that cytoreduction and HIPEC is a promising approach to offer to highly selected patients with peritoneal carcinomatosis from breast cancer and that this approach merit investigation in a larger series. Copyright © 2013 Elsevier Ltd. All rights reserved.

Treatment of peritoneal carcinomatosis from breast cancer by maximal cytoreduction and HIPEC: A preliminary report on 5 cases / Cardi, Maurizio; Sammartino, Paolo; FRAMARINO DEI MALATESTA, Marialuisa; Biacchi, Daniele; Cortesi, Enrico; Sibio, Simone; Accarpio, Fabio; Luciani, Claudio; Palazzo, Antonella; DI GIORGIO, Angelo. - In: THE BREAST. - ISSN 0960-9776. - 22:5(2013), pp. 845-849. [10.1016/j.breast.2013.02.020]

Treatment of peritoneal carcinomatosis from breast cancer by maximal cytoreduction and HIPEC: A preliminary report on 5 cases

CARDI, Maurizio;SAMMARTINO, Paolo;FRAMARINO DEI MALATESTA, Marialuisa;BIACCHI, DANIELE;CORTESI, Enrico;SIBIO, SIMONE;ACCARPIO, Fabio;LUCIANI, CLAUDIO;PALAZZO, ANTONELLA;DI GIORGIO, Angelo
2013

Abstract

Although peritoneal carcinomatosis from breast cancer is a rare event it frequently causes morbidity and mortality. Current literature provides scarce information on its management. We report outcomes in 5 patients (mean age 59.4 years) with peritoneal carcinomatosis from breast cancer treated with maximal cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) by the closed technique, at 40 °C for 1 h with cisplatin 75 mg/m(2). The primary breast cancer was a ductal carcinoma in 3 patients and a lobular carcinoma in 2. Mean peritoneal cancer index was 20.2. In 4 of the 5 patients surgery achieved macroscopic complete cytoreduction. One patient died of disease at 56 months, 4 are alive and disease-free at 13, 45, 74 and 128 months. These encouraging outcomes suggest that cytoreduction and HIPEC is a promising approach to offer to highly selected patients with peritoneal carcinomatosis from breast cancer and that this approach merit investigation in a larger series. Copyright © 2013 Elsevier Ltd. All rights reserved.
2013
cytoreduction; breast cancer; hipec; peritoneal metastases
01 Pubblicazione su rivista::01a Articolo in rivista
Treatment of peritoneal carcinomatosis from breast cancer by maximal cytoreduction and HIPEC: A preliminary report on 5 cases / Cardi, Maurizio; Sammartino, Paolo; FRAMARINO DEI MALATESTA, Marialuisa; Biacchi, Daniele; Cortesi, Enrico; Sibio, Simone; Accarpio, Fabio; Luciani, Claudio; Palazzo, Antonella; DI GIORGIO, Angelo. - In: THE BREAST. - ISSN 0960-9776. - 22:5(2013), pp. 845-849. [10.1016/j.breast.2013.02.020]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/515763
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 14
  • Scopus 27
  • ???jsp.display-item.citation.isi??? 22
social impact