The synthesis of a novel lipophilic diethylentriaminotetracetic( DTTA)-dodecane gadolinium complex is reported. The Gd-DTTA-dodecane complex is able to form mixed micelles with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and a nonionic surfactant like Tween 80. This novel multicomponent system can find potential application in magnetic resonance angiography (MRA).
Synthesis of a novel lipophilic gadolinium complex as a potential MRI contrast agent / Andrea, Masotti; Laura, Remollino; Carafa, Maria; Marianecci, Carlotta; Santucci, Eleonora; Ortaggi, Giancarlo. - In: SYNLETT. - ISSN 0936-5214. - 2006:17(2006), pp. 2815-2817. [10.1055/s-2006-950281]
Synthesis of a novel lipophilic gadolinium complex as a potential MRI contrast agent
CARAFA, Maria;MARIANECCI, CARLOTTA;SANTUCCI, Eleonora;ORTAGGI, Giancarlo
2006
Abstract
The synthesis of a novel lipophilic diethylentriaminotetracetic( DTTA)-dodecane gadolinium complex is reported. The Gd-DTTA-dodecane complex is able to form mixed micelles with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and a nonionic surfactant like Tween 80. This novel multicomponent system can find potential application in magnetic resonance angiography (MRA).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
