Intradural Extramedullary Spinal Melanocytoma (IESM) is an extremely uncommon tumour arising from the spinal leptomeninges; both from a gross pathology and microscopic point of view it can mimick its malignant counterpart, the Melanoma. Such tumours are usually solitary, with a lower proliferating rate and without obvious SC invasion. Their common differential diagnoses include Spinal Schwannoma and Spinal Meningiomas since they share a significant amount of radiological similarities. It is a relatively benign condition which is, to date, with no more than 24 previously reported cases, yet widely unexplored and poorly understood. We report the detailed clinical history of a 60 years old individual suffering from IESM and, by means of a thorough Literature review, the most relevant features concerning the epidemiological issues, the clinical course, the radiological appearance, the surgical results and the typical gross and microscopic pathology of a cohort of previously reported cases of IESM are extensively discussed and systematically investigated through statistical analyses in order to add to the relevant Literature a dedicated work concerning this rare and enigmatic condition.

Intradural extramidullary dorsal melanocytoma in the adult: case report and review of the literature / Armocida, Daniele; Pesce, Alessandro; Valentino Berra, Luigi; Marzetti, Francesco; Antonelli, Manila; Santoro, Antonio. - In: JOURNAL OF CLINICAL NEUROSCIENCE. - ISSN 0967-5868. - 62:(2019), pp. 248-253. [10.1016/j.jocn.2018.12.004]

Intradural extramidullary dorsal melanocytoma in the adult: case report and review of the literature

Daniele Armocida
Primo
;
Alessandro Pesce
Secondo
;
Francesco Marzetti;Manila Antonelli
Penultimo
;
Antonio Santoro
Ultimo
2019

Abstract

Intradural Extramedullary Spinal Melanocytoma (IESM) is an extremely uncommon tumour arising from the spinal leptomeninges; both from a gross pathology and microscopic point of view it can mimick its malignant counterpart, the Melanoma. Such tumours are usually solitary, with a lower proliferating rate and without obvious SC invasion. Their common differential diagnoses include Spinal Schwannoma and Spinal Meningiomas since they share a significant amount of radiological similarities. It is a relatively benign condition which is, to date, with no more than 24 previously reported cases, yet widely unexplored and poorly understood. We report the detailed clinical history of a 60 years old individual suffering from IESM and, by means of a thorough Literature review, the most relevant features concerning the epidemiological issues, the clinical course, the radiological appearance, the surgical results and the typical gross and microscopic pathology of a cohort of previously reported cases of IESM are extensively discussed and systematically investigated through statistical analyses in order to add to the relevant Literature a dedicated work concerning this rare and enigmatic condition.
2019
intradural extramedullary; MRI; melanocytoma; melanoma; spinal
01 Pubblicazione su rivista::01i Case report
Intradural extramidullary dorsal melanocytoma in the adult: case report and review of the literature / Armocida, Daniele; Pesce, Alessandro; Valentino Berra, Luigi; Marzetti, Francesco; Antonelli, Manila; Santoro, Antonio. - In: JOURNAL OF CLINICAL NEUROSCIENCE. - ISSN 0967-5868. - 62:(2019), pp. 248-253. [10.1016/j.jocn.2018.12.004]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1456078
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