Purpose A reliable model to simulate nuclear interactions is fundamental for Ion-therapy. We already showed how BLOB (“Boltzmann-Langevin One Body”), a model developed to simulate heavy ion interactions up to few hundreds of MeV/u, could simulate also 12C reactions in the same energy domain. However, its computation time is too long for any medical application. For this reason we present the possibility of emulating it with a Deep Learning algorithm. Methods The BLOB final state is a Probability Density Function (PDF) of finding a nucleon in a position of the phase space. We discretised this PDF and trained a Variational Auto-Encoder (VAE) to reproduce such a discrete PDF. As a proof of concept, we developed and trained a VAE to emulate BLOB in simulating the interactions of 12C with 12C at 62 MeV/u. To have more control on the generation, we forced the VAE latent space to be organised with respect to the impact parameter (b) training a classifier of b jointly with the VAE. Results The distributions obtained from the VAE are similar to the input ones and the computation time needed to use the VAE as a generator is negligible. Conclusions We show that it is possible to use a Deep Learning approach to emulate a model developed to simulate nuclear reactions in the energy range of interest for Ion-therapy. We foresee the implementation of the generation part in C++ and to interface it with the most used Monte Carlo toolkit: Geant4.

Preliminary results in using Deep Learning to emulate BLOB, a nuclear interaction model / Ciardiello, A.; Asai, M.; Caccia, B.; Cirrone, G. A. P.; Colonna, M.; Dotti, A.; Faccini, R.; Giagu, S.; Messina, A.; Napolitani, P.; Pandola, L.; Wright, D. H.; Mancini-Terracciano, C.. - In: PHYSICA MEDICA. - ISSN 1120-1797. - 73:(2020), pp. 65-72. [10.1016/j.ejmp.2020.04.005]

Preliminary results in using Deep Learning to emulate BLOB, a nuclear interaction model

Ciardiello, A.
Primo
;
Faccini, R.;Giagu, S.;Messina, A.;Mancini-Terracciano, C.
Ultimo
2020

Abstract

Purpose A reliable model to simulate nuclear interactions is fundamental for Ion-therapy. We already showed how BLOB (“Boltzmann-Langevin One Body”), a model developed to simulate heavy ion interactions up to few hundreds of MeV/u, could simulate also 12C reactions in the same energy domain. However, its computation time is too long for any medical application. For this reason we present the possibility of emulating it with a Deep Learning algorithm. Methods The BLOB final state is a Probability Density Function (PDF) of finding a nucleon in a position of the phase space. We discretised this PDF and trained a Variational Auto-Encoder (VAE) to reproduce such a discrete PDF. As a proof of concept, we developed and trained a VAE to emulate BLOB in simulating the interactions of 12C with 12C at 62 MeV/u. To have more control on the generation, we forced the VAE latent space to be organised with respect to the impact parameter (b) training a classifier of b jointly with the VAE. Results The distributions obtained from the VAE are similar to the input ones and the computation time needed to use the VAE as a generator is negligible. Conclusions We show that it is possible to use a Deep Learning approach to emulate a model developed to simulate nuclear reactions in the energy range of interest for Ion-therapy. We foresee the implementation of the generation part in C++ and to interface it with the most used Monte Carlo toolkit: Geant4.
2020
Monte Carlo simulations; Deep Learning; Nuclear reactions; Ion-therapy; Hadron-therapy
01 Pubblicazione su rivista::01a Articolo in rivista
Preliminary results in using Deep Learning to emulate BLOB, a nuclear interaction model / Ciardiello, A.; Asai, M.; Caccia, B.; Cirrone, G. A. P.; Colonna, M.; Dotti, A.; Faccini, R.; Giagu, S.; Messina, A.; Napolitani, P.; Pandola, L.; Wright, D. H.; Mancini-Terracciano, C.. - In: PHYSICA MEDICA. - ISSN 1120-1797. - 73:(2020), pp. 65-72. [10.1016/j.ejmp.2020.04.005]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1388631
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