Catalogo dei prodotti della ricerca

FIORILLO, ANNARITA
 Distribuzione geografica
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Continente #
NA - Nord America 1.601
EU - Europa 779
AS - Asia 317
AF - Africa 32
SA - Sud America 15
OC - Oceania 1
Totale 2.745
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Nazione #
US - Stati Uniti d'America 1.553
IT - Italia 457
SG - Singapore 124
IN - India 80
CN - Cina 75
SE - Svezia 75
DE - Germania 62
RU - Federazione Russa 47
FI - Finlandia 44
CA - Canada 40
TG - Togo 26
UA - Ucraina 26
ID - Indonesia 20
GB - Regno Unito 13
BR - Brasile 10
RO - Romania 10
FR - Francia 9
BG - Bulgaria 8
CH - Svizzera 8
MX - Messico 8
NL - Olanda 5
SA - Arabia Saudita 4
AR - Argentina 3
AT - Austria 3
EG - Egitto 3
IE - Irlanda 3
PH - Filippine 3
BA - Bosnia-Erzegovina 2
CO - Colombia 2
CZ - Repubblica Ceca 2
JP - Giappone 2
KR - Corea 2
PK - Pakistan 2
PL - Polonia 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
AU - Australia 1
BE - Belgio 1
ES - Italia 1
GR - Grecia 1
SC - Seychelles 1
TN - Tunisia 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 2.745
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Città #
Fairfield 267
Rome 237
Ashburn 154
Woodbridge 136
Seattle 99
Singapore 95
Chandler 89
Houston 84
Wilmington 78
Cambridge 69
Princeton 45
Ann Arbor 43
Santa Clara 43
San Paolo di Civitate 37
Millbury 29
Plano 28
Lawrence 27
Lomé 26
Ottawa 26
San Diego 26
Beijing 25
Helsinki 25
Dearborn 24
Jakarta 20
Bremen 17
Milan 15
Boston 13
Andover 12
Toronto 12
Moscow 11
Fremont 10
Jacksonville 8
Sofia 8
Grotteria 7
Boardman 6
Naples 6
New York 6
Norwalk 6
Trieste 6
Ferentino 5
Florence 5
Frankfurt am Main 5
Geneva 5
Munich 5
Queens 5
Bologna 4
Bühl 4
Falkenstein 4
Kunming 4
London 4
Los Angeles 4
Phoenix 4
Riyadh 4
Berlin 3
Campinas 3
Catania 3
Federal 3
Fiumicino 3
Germantown 3
Guangzhou 3
Gustavo Adolfo Madero 3
Hefei 3
Nanjing 3
Nuremberg 3
Washington 3
Amsterdam 2
Bari 2
Bengaluru 2
Bogotá 2
Bugry 2
Changsha 2
Chongqing 2
Dublin 2
Falls Church 2
Fasano 2
Fauglia 2
Gurugram 2
Kusadasi 2
Lappeenranta 2
Latina 2
Laurel 2
Manila 2
Marino 2
Mexico City 2
Mostar 2
Nanchang 2
New Delhi 2
Nürnberg 2
Oxford 2
Pescara 2
Pistoia 2
Pittsburgh 2
Ponticelli 2
Prague 2
Pune 2
Redwood City 2
Rieti 2
Rio de Janeiro 2
Ronciglione 2
San Mateo 2
Totale 2.043
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Nome #
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 137
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 114
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 113
Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase 111
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase 89
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation 86
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme 85
Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations 85
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 83
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus- structural basis of substrate recognition. 80
The crystal structure of Giardia duodenalis 14-3-3 in the apo form: When protein post-translational modifications make the difference 80
Structural basis of Sorcin-mediated calcium-dependent signal transduction 78
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review 76
Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells 76
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 76
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. 74
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress 72
The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway. 68
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 67
Sorcin, a calcium binding protein involved in the multidrug resistance mechanisms in cancer cells 67
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? 66
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 66
Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes 63
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity 61
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme 57
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach 56
Crystallization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus. 55
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target 55
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Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography 51
Inhibition of Leishmania infantum trypanothione reductase by NADPH, its natural substrate 45
null 44
Silver Ion Incorporation and Nanoparticle Formation inside the Cavity of Pyrococcus furiosus Ferritin: Structural and Size-Distribution Analyses 41
Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design 37
Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa 37
Re-discovery of giardiavirus: Genomic and functional analysis of viruses from giardia duodenalis isolates 37
Fragment merging, growing, and linking identify new trypanothione reductase inhibitors for Leishmaniasis 35
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Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin 35
null 31
null 27
Investigation of the entry pathway and molecular nature of σ1 receptor ligands 26
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 26
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 22
AI is a viable alternative to high throughput screening: a 318-target study 21
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 21
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions 20
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 19
null 17
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 15
Study of manganese binding to the ferroxidase centre of human H-type ferritin 14
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Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases 12
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The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target 6
Totale 2.948
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Categoria #
all - tutte 10.084
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.084
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020186 0 0 0 0 0 0 0 56 48 39 22 21
2020/2021333 27 20 6 26 5 48 21 14 29 98 19 20
2021/2022445 32 24 29 20 47 19 9 51 37 37 72 68
2022/2023474 93 107 24 37 48 27 13 20 61 8 19 17
2023/2024347 16 28 16 24 28 64 10 44 9 40 37 31
2024/2025513 23 30 70 111 62 71 95 51 0 0 0 0
Totale 2.948