FIORILLO, ANNARITA
FIORILLO, ANNARITA
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition.
2012 Ilari, Andrea; Baiocco, P; Messori, L; Fiorillo, Annarita; Boffi, Alberto; Gramiccia, M; Di Muccio, T; Colotti, G.
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis
2017 Ilari, Andrea; Fiorillo, Annarita; Genovese, Ilaria; Colotti, Gianni
Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells
2017 Genovese, Ilaria; Fiorillo, Annarita; Ilari, Andrea; Masciarelli, Silvia; Fazi, Francesco; Colotti, Gianni
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus- structural basis of substrate recognition.
2009 Ilari, Andrea; Fiorillo, A; Angelaccio, Sebastiana; Florio, Rita; Chiaraluce, Roberta; VAN DER OOST, J; Consalvi, Valerio
Crystallization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus.
2004 Ilari, Andrea; Angelaccio, Sebastiana; Fiorillo, Annarita; Florio, Rita; Consalvi, Valerio; Chiaraluce, Roberta
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?
2017 Morea, Veronica; Bidollari, Eris; Colotti, Gianni; Fiorillo, Annarita; Rosati, Jessica Diana; De Filippis, Lidia; Squitieri, Ferdinando; Ilari, Andrea
Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin
2021 Fiorillo, A.; Morea, V.; Colotti, G.; Ilari, A.
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase
2021 Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto
Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography
2013 Baiocco, P.; Poce, Giovanna; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; Colotti, G.; Biava, Mariangela; Moraca, F.; Botta, M.; Yardley, V.; Fiorillo, A.; Lantella, A.; Malatesta, Francesco; Ilari, Andrea
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives
2017 Saccoliti, Francesco; Angiulli, Gabriella; Pupo, Giovanni; Pescatori, Luca; Madia, VALENTINA NOEMI; Messore, Antonella; Colotti, Gianni; Fiorillo, Annarita; Scipione, Luigi; Gramiccia, Marina; Di Muccio, Trentina; DI SANTO, Roberto; Costi, Roberta; Ilari, Andrea
Inhibition of Leishmania infantum trypanothione reductase by NADPH, its natural substrate
2012 Lantella, Antonella; Giorgi, Alessandra; Baiocco, Paola; Fiorillo, Annarita; Schinina', Maria Eugenia; G., Colotti; Ilari, Andrea; Malatesta, Francesco
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress
2013 Ardini, Matteo; Fiorillo, Annarita; Fittipaldi, Maria; Stefanini, Simonetta; Gatteschi, Dante; Ilari, Andrea; Chiancone, Emilia
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells
2021 Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A.
Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases
2018 Colotti, Gianni; Fiorillo, Annarita; Ilari, Andrea
Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes
2013 Colotti, Gianni; Ilari, Andrea; Fiorillo, Annarita; Baiocco, Paola; Cinellu, Maria Agostina; Maiore, Laura; Scaletti, Federica; Gabbiani, Chiara; Messori, Luigi
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents
2018 Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions
2015 Cau, Ylenia; Fiorillo, Annarita; Mori, Mattia; Ilari, Andrea; Botta, Maurizo; Lalle, Marco
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach
2022 Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G.
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome
2020 Genovese, I.; Carotti, A.; Ilari, A.; Fiorillo, A.; Battista, T.; Colotti, G.; Ivarsson, Y.
Re-discovery of giardiavirus: Genomic and functional analysis of viruses from giardia duodenalis isolates
2021 Marucci, G.; Zullino, I.; Bertuccini, L.; Camerini, S.; Cecchetti, S.; Pietrantoni, A.; Casella, M.; Vatta, P.; Greenwood, A. D.; Fiorillo, A.; Lalle, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. | 2012 | Ilari, Andrea; Baiocco, P; Messori, L; Fiorillo, Annarita; Boffi, Alberto; Gramiccia, M; Di Muccio, T; Colotti, G. | |
| An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis | 2017 | Ilari, Andrea; Fiorillo, Annarita; Genovese, Ilaria; Colotti, Gianni | |
| Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells | 2017 | Genovese, Ilaria; Fiorillo, Annarita; Ilari, Andrea; Masciarelli, Silvia; Fazi, Francesco; Colotti, Gianni | |
| Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus- structural basis of substrate recognition. | 2009 | Ilari, Andrea; Fiorillo, A; Angelaccio, Sebastiana; Florio, Rita; Chiaraluce, Roberta; VAN DER OOST, J; Consalvi, Valerio | |
| Crystallization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus. | 2004 | Ilari, Andrea; Angelaccio, Sebastiana; Fiorillo, Annarita; Florio, Rita; Consalvi, Valerio; Chiaraluce, Roberta | |
| Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? | 2017 | Morea, Veronica; Bidollari, Eris; Colotti, Gianni; Fiorillo, Annarita; Rosati, Jessica Diana; De Filippis, Lidia; Squitieri, Ferdinando; Ilari, Andrea | |
| Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin | 2021 | Fiorillo, A.; Morea, V.; Colotti, G.; Ilari, A. | |
| Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase | 2021 | Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto | |
| Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography | 2013 | Baiocco, P.; Poce, Giovanna; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; Colotti, G.; Biava, Mariangela; Moraca, F.; Botta, M.; Yardley, V.; Fiorillo, A.; Lantella, A.; Malatesta, Francesco; Ilari, Andrea | |
| Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives | 2017 | Saccoliti, Francesco; Angiulli, Gabriella; Pupo, Giovanni; Pescatori, Luca; Madia, VALENTINA NOEMI; Messore, Antonella; Colotti, Gianni; Fiorillo, Annarita; Scipione, Luigi; Gramiccia, Marina; Di Muccio, Trentina; DI SANTO, Roberto; Costi, Roberta; Ilari, Andrea | |
| Inhibition of Leishmania infantum trypanothione reductase by NADPH, its natural substrate | 2012 | Lantella, Antonella; Giorgi, Alessandra; Baiocco, Paola; Fiorillo, Annarita; Schinina', Maria Eugenia; G., Colotti; Ilari, Andrea; Malatesta, Francesco | |
| Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress | 2013 | Ardini, Matteo; Fiorillo, Annarita; Fittipaldi, Maria; Stefanini, Simonetta; Gatteschi, Dante; Ilari, Andrea; Chiancone, Emilia | |
| Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells | 2021 | Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A. | |
| Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases | 2018 | Colotti, Gianni; Fiorillo, Annarita; Ilari, Andrea | |
| Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes | 2013 | Colotti, Gianni; Ilari, Andrea; Fiorillo, Annarita; Baiocco, Paola; Cinellu, Maria Agostina; Maiore, Laura; Scaletti, Federica; Gabbiani, Chiara; Messori, Luigi | |
| Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents | 2018 | Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni | |
| Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions | 2015 | Cau, Ylenia; Fiorillo, Annarita; Mori, Mattia; Ilari, Andrea; Botta, Maurizo; Lalle, Marco | |
| Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach | 2022 | Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G. | |
| Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome | 2020 | Genovese, I.; Carotti, A.; Ilari, A.; Fiorillo, A.; Battista, T.; Colotti, G.; Ivarsson, Y. | |
| Re-discovery of giardiavirus: Genomic and functional analysis of viruses from giardia duodenalis isolates | 2021 | Marucci, G.; Zullino, I.; Bertuccini, L.; Camerini, S.; Cecchetti, S.; Pietrantoni, A.; Casella, M.; Vatta, P.; Greenwood, A. D.; Fiorillo, A.; Lalle, M. |