Catalogo dei prodotti della ricerca

COLOTTI, GIANNI
 Distribuzione geografica
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Continente #
NA - Nord America 1.243
EU - Europa 979
AS - Asia 437
SA - Sud America 52
AF - Africa 27
Totale 2.738
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Nazione #
US - Stati Uniti d'America 1.192
IT - Italia 674
SG - Singapore 230
CN - Cina 79
IN - India 69
SE - Svezia 63
DE - Germania 53
BR - Brasile 44
CA - Canada 43
RU - Federazione Russa 42
FI - Finlandia 31
GB - Regno Unito 24
ID - Indonesia 22
TG - Togo 18
FR - Francia 11
NL - Olanda 10
AT - Austria 8
BG - Bulgaria 8
IE - Irlanda 8
RO - Romania 8
UA - Ucraina 8
CH - Svizzera 7
IR - Iran 6
MX - Messico 6
PH - Filippine 5
PT - Portogallo 5
AR - Argentina 4
BE - Belgio 4
KR - Corea 4
LT - Lituania 4
SA - Arabia Saudita 4
TR - Turchia 4
PK - Pakistan 3
AL - Albania 2
AZ - Azerbaigian 2
CL - Cile 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
EG - Egitto 2
ES - Italia 2
JP - Giappone 2
UZ - Uzbekistan 2
ZA - Sudafrica 2
AE - Emirati Arabi Uniti 1
AO - Angola 1
BD - Bangladesh 1
BY - Bielorussia 1
BZ - Belize 1
CI - Costa d'Avorio 1
CO - Colombia 1
DZ - Algeria 1
GE - Georgia 1
IQ - Iraq 1
JM - Giamaica 1
LV - Lettonia 1
MK - Macedonia 1
NG - Nigeria 1
PE - Perù 1
TN - Tunisia 1
VN - Vietnam 1
Totale 2.738
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Città #
Rome 312
Fairfield 159
Ashburn 115
Singapore 93
Woodbridge 87
Seattle 83
Houston 77
Wilmington 67
Chandler 58
Cambridge 51
Santa Clara 46
San Paolo di Civitate 35
Ottawa 32
Ann Arbor 30
Princeton 30
Helsinki 25
Millbury 24
San Diego 23
Beijing 22
Jakarta 21
Milan 21
New York 21
Lawrence 20
Lomé 18
Bremen 17
Dearborn 15
Fremont 13
Plano 12
Moscow 11
Nuremberg 11
Cosenza 10
Florence 10
Frosinone 8
Sofia 8
Andover 7
Boston 7
Dublin 7
Toronto 7
Boardman 6
Fiumicino 6
Grotteria 6
Lambeth 6
Los Angeles 6
Naples 6
Redwood City 6
Tehran 6
Urbino 6
Campinas 5
Council Bluffs 5
Falkenstein 5
Latina 5
Lisbon 5
Pasig 5
Queens 5
Shanghai 5
Washington 5
Bay Shore 4
Chicago 4
Civitanova Marche 4
Frankfurt am Main 4
Kunming 4
London 4
Modena 4
Norwalk 4
Phoenix 4
Riyadh 4
Trieste 4
Verona 4
Aviatico 3
Bologna 3
Brussels 3
Bühl 3
Catania 3
Cerveteri 3
Chongqing 3
Fuzhou 3
Germantown 3
Gustavo Adolfo Madero 3
Islington 3
Kolkata 3
Pune 3
Yubileyny 3
Afragola 2
Ardea 2
Berlin 2
Birmingham 2
Bugry 2
Cairo 2
Ceccano 2
Centallo 2
Cinquefrondi 2
Cornaredo 2
Curitiba 2
Delhi 2
Duncan 2
Ercolano 2
Fasano 2
Ferentino 2
Filettino 2
Forlì 2
Totale 1.838
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Nome #
Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an nadph:o2 oxidoreductase activity shared by glutathione reductase 149
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 147
Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b 123
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 120
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects 113
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 102
Bcl-2 family inhibitors sensitize human cancer models to therapy 101
Targeting the anti-apoptotic Bcl-2 family proteins: Machine learning virtual screening and biological evaluation of new small molecules 100
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 94
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 90
Identification of small molecule inhibitors of the aurora-A/TPX2 complex 88
Use of ferritin-based metal-encapsulated nanocarriers as anticancer agents 87
Structural basis of Sorcin-mediated calcium-dependent signal transduction 82
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 81
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 77
Taxanes in cancer treatment: activity, chemoresistance and its overcoming 77
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity 77
Use of organoids in medicinal chemistry: challenges on ethics and biosecurity 76
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? 71
null 64
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme 64
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach 62
ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity 61
Doxorubicin and other anthracyclines in cancers: activity, chemoresistance and its overcoming 59
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target 58
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability 52
null 45
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 45
Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design 42
Inhibitory effect of silver nanoparticles on trypanothione reductase activity and leishmania infantum proliferation 41
Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin 41
Molecular basis of antimony treatment in leishmaniasis 40
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 37
null 35
Sorcin promotes cell proliferation, migration and invasion in cancer by regulating the EGF-dependent EGFR signaling pathways 34
Trypanothione reductase from leishmania infantum: cloning, expression, purification, crystallization and preliminary x-ray data analysis 33
Regulation of the EGFR endocytic route by an Endoplasmic Reticulum-related Ca2+ binding protein. 31
Investigation of the entry pathway and molecular nature of σ1 receptor ligands 30
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 29
null 28
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 26
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 24
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 24
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 23
Widespread in vivo efficacy of The-0504: a conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers 20
null 17
null 12
null 12
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate 8
EGF receptor in organ development, tissue homeostasis and regeneration 8
Totale 2.960
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Categoria #
all - tutte 10.433
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.433
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020121 0 0 0 0 0 0 0 0 40 31 30 20
2020/2021332 36 27 9 22 3 58 19 10 24 82 23 19
2021/2022350 16 20 26 13 42 14 7 33 37 21 76 45
2022/2023447 65 90 14 35 33 19 37 22 47 27 33 25
2023/2024510 36 40 37 47 52 92 36 43 11 31 49 36
2024/2025759 33 33 47 108 74 74 92 91 207 0 0 0
Totale 2.960