Catalogo dei prodotti della ricerca

COLOTTI, GIANNI
 Distribuzione geografica
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Continente #
NA - Nord America 1.226
EU - Europa 805
AS - Asia 306
AF - Africa 21
SA - Sud America 6
Totale 2.364
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Nazione #
US - Stati Uniti d'America 1.178
IT - Italia 580
SG - Singapore 116
CN - Cina 80
IN - India 68
SE - Svezia 64
CA - Canada 43
DE - Germania 37
FI - Finlandia 25
ID - Indonesia 22
GB - Regno Unito 21
TG - Togo 18
RU - Federazione Russa 11
BG - Bulgaria 8
FR - Francia 8
IE - Irlanda 8
RO - Romania 8
CH - Svizzera 7
UA - Ucraina 7
IR - Iran 6
AT - Austria 5
PH - Filippine 5
BR - Brasile 4
MX - Messico 4
SA - Arabia Saudita 4
BE - Belgio 3
NL - Olanda 3
TR - Turchia 3
DK - Danimarca 2
ES - Italia 2
LT - Lituania 2
AR - Argentina 1
BZ - Belize 1
CI - Costa d'Avorio 1
CZ - Repubblica Ceca 1
EG - Egitto 1
KR - Corea 1
LV - Lettonia 1
MK - Macedonia 1
PE - Perù 1
PK - Pakistan 1
PT - Portogallo 1
TN - Tunisia 1
Totale 2.364
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Città #
Rome 256
Fairfield 159
Ashburn 115
Woodbridge 87
Seattle 84
Singapore 79
Houston 77
Wilmington 67
Chandler 58
Cambridge 51
Santa Clara 49
San Paolo di Civitate 35
Ottawa 32
Ann Arbor 30
Princeton 30
Millbury 24
San Diego 23
Beijing 22
Jakarta 21
New York 21
Lawrence 20
Helsinki 19
Milan 19
Bremen 18
Lomé 18
Dearborn 15
Fremont 13
Plano 12
Florence 10
Frosinone 8
Sofia 8
Andover 7
Boston 7
Dublin 7
Toronto 7
Fiumicino 6
Lambeth 6
Moscow 6
Redwood City 6
Tehran 6
Urbino 6
Latina 5
London 5
Naples 5
Pasig 5
Queens 5
Shanghai 5
Washington 5
Bay Shore 4
Boardman 4
Chicago 4
Civitanova Marche 4
Kunming 4
Norwalk 4
Phoenix 4
Riyadh 4
Trieste 4
Aviatico 3
Bologna 3
Bühl 3
Catania 3
Cerveteri 3
Chongqing 3
Fuzhou 3
Germantown 3
Gustavo Adolfo Madero 3
Islington 3
Los Angeles 3
Pune 3
Afragola 2
Ardea 2
Berlin 2
Birmingham 2
Brussels 2
Bugry 2
Ceccano 2
Centallo 2
Cinquefrondi 2
Delhi 2
Duncan 2
Ercolano 2
Falkenstein 2
Fasano 2
Ferentino 2
Filettino 2
Forlì 2
Geneva 2
Gurugram 2
Hefei 2
Hyderabad 2
Jinan 2
Kingston 2
Kolkata 2
Kusadasi 2
Mannheim 2
Marino 2
Modena 2
Montreal 2
Nanjing 2
New Delhi 2
Totale 1.713
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Nome #
Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an nadph:o2 oxidoreductase activity shared by glutathione reductase 145
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 132
Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b 118
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 112
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects 101
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 90
Use of ferritin-based metal-encapsulated nanocarriers as anticancer agents 85
Targeting the anti-apoptotic Bcl-2 family proteins: Machine learning virtual screening and biological evaluation of new small molecules 85
Identification of small molecule inhibitors of the aurora-A/TPX2 complex 82
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 80
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 80
Structural basis of Sorcin-mediated calcium-dependent signal transduction 77
Bcl-2 family inhibitors sensitize human cancer models to therapy 75
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 74
Use of organoids in medicinal chemistry: challenges on ethics and biosecurity 74
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity 74
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? 64
null 64
Taxanes in cancer treatment: activity, chemoresistance and its overcoming 63
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 59
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme 54
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target 54
null 45
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach 45
Doxorubicin and other anthracyclines in cancers: activity, chemoresistance and its overcoming 44
ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity 42
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability 39
Inhibitory effect of silver nanoparticles on trypanothione reductase activity and leishmania infantum proliferation 38
Molecular basis of antimony treatment in leishmaniasis 36
null 35
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 33
Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design 32
Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin 32
Trypanothione reductase from leishmania infantum: cloning, expression, purification, crystallization and preliminary x-ray data analysis 29
Sorcin promotes cell proliferation, migration and invasion in cancer by regulating the EGF-dependent EGFR signaling pathways 26
Regulation of the EGFR endocytic route by an Endoplasmic Reticulum-related Ca2+ binding protein. 25
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 25
Investigation of the entry pathway and molecular nature of σ1 receptor ligands 22
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 20
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 19
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 19
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 18
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 18
null 17
null 16
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate 14
Widespread in vivo efficacy of The-0504: a conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers 13
null 12
null 12
Totale 2.568
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Categoria #
all - tutte 9.168
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 9.168
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020287 0 0 0 0 0 62 63 41 40 31 30 20
2020/2021332 36 27 9 22 3 58 19 10 24 82 23 19
2021/2022350 16 20 26 13 42 14 7 33 37 21 76 45
2022/2023449 65 90 14 36 33 19 37 22 48 27 33 25
2023/2024519 36 41 37 50 53 93 36 44 11 32 50 36
2024/2025356 33 33 48 109 78 55 0 0 0 0 0 0
Totale 2.568