COSTI, Roberta
 Distribuzione geografica
Continente #
NA - Nord America 7.357
EU - Europa 3.325
AS - Asia 1.247
SA - Sud America 93
AF - Africa 81
OC - Oceania 30
Continente sconosciuto - Info sul continente non disponibili 4
Totale 12.137
Nazione #
US - Stati Uniti d'America 7.227
IT - Italia 1.554
SG - Singapore 389
IN - India 382
SE - Svezia 327
CN - Cina 320
UA - Ucraina 312
IE - Irlanda 285
FI - Finlandia 254
DE - Germania 128
CA - Canada 115
GB - Regno Unito 102
BG - Bulgaria 94
AT - Austria 78
AR - Argentina 70
TG - Togo 57
ES - Italia 38
FR - Francia 34
IR - Iran 32
AU - Australia 29
RO - Romania 24
PK - Pakistan 20
TR - Turchia 20
CH - Svizzera 19
JP - Giappone 19
BE - Belgio 18
HK - Hong Kong 17
BR - Brasile 14
KR - Corea 13
GR - Grecia 12
NL - Olanda 10
MX - Messico 9
PL - Polonia 9
RU - Federazione Russa 8
EG - Egitto 7
CL - Cile 6
MY - Malesia 6
TW - Taiwan 6
UG - Uganda 6
ZA - Sudafrica 6
VN - Vietnam 4
EE - Estonia 3
LV - Lettonia 3
NO - Norvegia 3
PA - Panama 3
AP - ???statistics.table.value.countryCode.AP??? 2
CI - Costa d'Avorio 2
CY - Cipro 2
CZ - Repubblica Ceca 2
EU - Europa 2
ID - Indonesia 2
IL - Israele 2
JM - Giamaica 2
OM - Oman 2
PE - Perù 2
PT - Portogallo 2
RS - Serbia 2
SA - Arabia Saudita 2
SC - Seychelles 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BY - Bielorussia 1
BZ - Belize 1
DK - Danimarca 1
EC - Ecuador 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LT - Lituania 1
MA - Marocco 1
MN - Mongolia 1
NZ - Nuova Zelanda 1
TH - Thailandia 1
Totale 12.137
Città #
Fairfield 995
Chandler 684
Rome 678
Ashburn 584
Woodbridge 533
Houston 368
Wilmington 330
Seattle 323
Cambridge 318
Ann Arbor 283
Dublin 274
Singapore 226
Princeton 194
Dearborn 162
Plano 154
Boston 120
Jacksonville 113
San Paolo di Civitate 108
Helsinki 105
Lawrence 105
Tampa 101
New York 98
Beijing 95
Des Moines 90
Millbury 90
San Diego 80
Boardman 67
Federal 65
Sofia 60
Vienna 60
Ottawa 58
Andover 57
Lomé 57
Washington 52
Philadelphia 47
Toronto 44
Milan 35
Norwalk 34
Barcelona 33
Perugia 31
Fasano 29
Shanghai 29
Falls Church 27
Redwood City 26
Florence 25
Santa Clara 25
Fremont 24
Kunming 21
Mannheim 21
Sydney 21
Buffalo 20
Mentana 20
Grafing 19
Nanjing 18
Hefei 17
Naples 17
Bremen 16
Brussels 16
Bühl 16
Urbino 15
London 14
Pessac 14
Viterbo 14
Zurich 14
Ahmedabad 13
Guangzhou 13
Palermo 13
Auburn Hills 12
Gainesville 12
Athens 11
Los Angeles 11
Adana 10
Bologna 10
Dallas 10
Galdo 10
Hong Kong 10
Vigevano 10
Chiyoda-ku 9
Hyderabad 9
Chicago 8
Jinan 8
Karachi 8
Kolkata 8
Lappeenranta 8
St Louis 8
Bari 7
Berlin 7
Edinburgh 7
Fuzhou 7
Memphis 7
Munich 7
Nanchang 7
Pomezia 7
Ardea 6
Fort Worth 6
Genoa 6
Kampala 6
Marietta 6
Mestre 6
Montelibretti 6
Totale 8.698
Nome #
Inhibition of Polycomb Repressive Complex2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings 148
Design, synthesis and evaluation of 3,4-dihydroxybenzoic acid derivatives as antioxidants, bio-metal chelating agents and acetylcholinesterase inhibitors 139
Discovery of a pyrimidine compound endowed with antitumor activity 134
Design, synthesis, and biological evaluation of new 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents 129
Comparison of different methods for the extraction of cannabinoids from cannabis 127
Structure−activity relationship of pyrrolyl diketo acid derivatives as dual Inhibitors of HIV‑1 integrase and reverse transcriptase ribonuclease H domain 119
N‑substituted quinolinonyl diketo acid derivatives as HIV integrase strand transfer inhibitors and their activity against RNase H function of reverse transcriptase 118
Regioselectivity of the methyl-TosMIC reaction with substituted ethyl cinnamates 114
Activity of caffeic acid derivatives against Candida albicans biofilm 114
Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents 112
Antifungal Agents. 5. Chloro and Amino Derivatives of 1,2-Diaryl-1-(1H-imidazol-1-yl)ethane with Potent Antifungal Activities. 111
Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action 111
Towards a new application of amaranth seed oil as an agent against Candida albicans 110
1,2,5-Benzothiadiazepine and Pyrrolo[2,1-d][1,2,5]Benzothiadiazepine Derivatives with Anti-HIV-1 Activity. 108
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 106
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 105
Analytical characterization of an inulin-type fructooligosaccharide from root-tubers of Asphodelus ramosus L 105
Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors 104
Searching for new agents active against candida albicans biofilm: a series of indole derivatives, design, synthesis and biological evaluation 102
Research on Nitrogen Containing Heterocyclic Compounds. XX. Synthesis of 8H-Imidazo[5,1-c]pyrrolo[1,2-a][1,4]benzodiazepine and its 6-Derivatives. 101
Investigation of Commiphora myrrha (Nees) Engl. oil and its main components for antiviral activity 101
Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties 100
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents 100
Design, synthesis and biological evaluation of new pyrimidine derivatives as anticancer agents 100
Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans 98
Design, synthesis, and In vitro, in silico and in cellulo evaluation of new Pyrimidine and Pyridine amide and Carbamate derivatives as multi-functional Cholinesterase Inhibitors 96
Synthesis, biological evaluation and structure-activity correlation study of a series of imidazol-based compounds as Candida albicans inhibitors 95
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach. 94
New Inhibitors of the human p300/CBP acetyltransferase are selectively active against the Arabidopsis HAC proteins 93
Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study 89
Pyrrolyl pyrazoles as non-diketo acid inhibitors of the HIV-1 ribonuclease H function of reverse transcriptase 88
Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans 88
New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation 87
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation 87
New promising compounds with in vitro nanomolar activity against Trypanosoma cruzi 86
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75 84
Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity 84
4-Substituted 2-phenyl- and 2-phenyl-3-aryl pyrroles by reaction of tosylbenzyl isocyanide (TosBIC) with Michael acceptors. 82
Synthesis of Novel HEPT Analogues with Anti-HIV-1 Activity. 82
Novel benzazole derivatives endowed with potent antiheparanase activity 82
1-Arylsulfonyl-3-(a-hydroxybenzyl)-1H-pyrroles, a novel class of anti-HIV-1 reverse transcriptase inhibitors. 82
Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines 82
Pyrrolyl and indolyl α-γ-diketo acid derivatives acting as selective inhibitors of human carbonic anhydrases IX and XII 81
Arylthiopyrrole (ATP) Derivatives as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors 81
HIV-1 Integrase Inhibitors that Block HIV-1 Replication in Infected Cells. Planning Synthetic Derivatives from Natural Products 81
Antimycobacterial Pyrroles: Synthesis, Anti-Mycobacterium tuberculosis Activity and QSAR Studies. 80
Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole: Synthesis, anti-Candida activity, and QSAR studies 80
N-(1-Naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-ylmethyl)methylamines Related to Naftifine. Synthesis and Antifungal Activity. 80
From Iloperidone to new Sigma1 agonists: a structure-based approach for Huntington's disease treatment. 79
Simple synthesis of deuterated pterosines 79
Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase 79
Influence of oral administration mode on the efficacy of commercial bovine Lactoferrin against iron and inflammatory homeostasis disorders 79
New Nucleotide-Competitive Non-Nucleoside Inhibitors of Terminal 2 Deoxynucleotidyl Transferase: Discovery, Characterization, and 3 Crystal Structure in Complex with the Target 79
2H-Pyrrolo[3,4-b][1,5] benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase 78
Novel Heterocyclic Systems. Synthesis of 10H-Pyrrolo[1,2-b][1,2,5]benzothiadiazocine 5,5-Dioxide and Related Derivatives. 78
Hypoglycemic activity of curcumin synthetic analogues in alloxan-induced diabetic rats 76
Toxicological aspects of cannabinoid, pesticide and metal levels detected in light Cannabis inflorescences grown in Italy 76
In vitro antiviral activity of new oxazoline derivatives as potent poliovirus inhibitors 75
Ptaquiloside in Pteridium aquilinum subsp. aquilinum and corresponding soils from South of Italy: influence of physical and chemical features of soils on its occurrence 75
Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity 74
New pyrimidine and pyridine derivatives as multitarget cholinesterase inhibitors. Design, synthesis, and in vitro and in cellulo evaluation 74
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 73
Novel Curcumin Derivatives as p300 Histone Acetyltransferases inhibitors 73
Novel In Vitro Highly Active Antifungal Agents With Pyrrole and Imidazole Moieties. 73
6-Aryl-2,4-dioxo-5-hexenoic Acids, Novel Integrase Inhibitors Active Against HIV-1 Multiplication in Cell-Based Assays. 73
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells 73
Synthesis of Pyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione, a Model System Useful for the Design of 11-Oxosibiromycinone Analogues. 72
6-(1-(4-fluorophenyl)methyl-1H-pyrrol-2-yl))-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro 72
1-[4-(4-Chlorophenyl)-1H-pyrrol-3-yl](2,4-dichlorophenyl)methyl-1H-imidazole (RDS 416) 71
Tegaserod for the treatment of Irritable Bowel syndrome 71
Perturbing Effects of Chiral Stationary Phase on Enantiomerization Second-Order Rate Constants Determined by Enantioselective Dynamic High-Performance Liquid Chromatography: A Practical Tool to Quantify the Accessible Acid and Basic Catalytic Sites Bonded on Chromatographic Supports 70
New deferiprone derivatives as multi-functional cholinesterase inhibitors. Design, synthesis and in vitro evaluation 70
Structure-activity relationship studies on potential non-nucleoside DABO-like inhibitors of HIV-1 reverse transcriptase. 69
Derivatives of 2,3-dihydroimidazo[1,5,4-ef][1,2,5]benzothiadiazepin-6(4H,7H)-thione 1,1-dioxide, a new heterocyclic system related to TIBO 68
Ultrastructural damages to H1N1 influenza virus caused by vapor essential oils 67
Probing HIV-1 integrase inhibitor binding sites with position-specific integrase-DNA cross-linking assays 66
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: Design, synthesis, biological activities, and mechanism of action 66
Quinolinonyl non-diketo acid derivatives as Inhibitors of HIV-1 ribonuclease H and polymerase functions of reverse transcriptase 66
Pyrrolnitrin and Related Pyrroles Endowed with Antibacterial Activities against Mycobacterium Tuberculosis. 65
2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays 65
Antifungal estrogen-like imidazoles. Synthesis and antifungal activities of thienyl and 1H-pyrrolyl derivatives of 1-aryl-2-(1H-imidazol-1-yl)ethane. 64
Geometrically and Conformationally Restrained Cinnamoyl-Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation and Molecular Modeling 64
Simple Synthetic Approach to Arylacetic NSAIAs via TosMIC Procedure. 64
Functional roles of Acetylated Histone marks at mouse meiotic recombination hotspots 64
Acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease–a patent review (2016–present) 64
Enantioselective liquid Chromatography of C3-chiral 2,3-dihydro-1,2,5-benzothiadiazepin-4(5H)-one and thione 1,1-dioxides on polyacrylamide- and polysaccaride-based chiral stationary phases 63
Evaluation of HIV-1 integrase inhibitors on human primary macrophages using a luciferase-based single-cycle phenotypicassay 63
HIV-1 Integrase Inhibitors That Block HIV-1 Replication in Infected Cells: Planning Synthetic Derivatives from Natural Products. 62
Selective inhibition of the PRC2 methyltransferase activity suppresses trimethylation of H3K27 in Arabidopsis seeds 62
Arylthiopyrrole (AThP) Derivatives as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Synthesis, Structure-Activity Relationships and Docking Studies. Part 1. 62
Small-molecule inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H function. Challenges and recent developments 62
Discovery and Pharmacological Profile of New 1H‑Indazole-3- carboxamide and 2H‑Pyrrolo[3,4‑c]quinoline Derivatives as SelectiveSerotonin 4 Receptor Ligands 62
Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors 62
Acidi 6-Aril-2,4-dioxo-5-esenoici, Nuovi Inibitori dell’Integrasi. Blocco la Replicazione dell’HIV-1 in Cellule Infettate. 61
CONVENIENT ROUTE TO 2H-PYRROLO [3,4-b]QUINOLIN-9(4H)-ONE SKELETON VIA TOSMIC REACTION 61
Diaryl disulfides as novel stabilizers of tumor suppressor Pdcd4 61
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 61
Aminopyrimidine derivatives as new protein kinase inhibitors endowed with anticancer activity. 59
A General, Versatile Synthesis of 2H-Pyrrolo[3,4-c]quinolines via Tosylmethylisocyanide Reaction 59
Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: Enzyme selectivity and cellular activity 59
Totale 8.343
Categoria #
all - tutte 37.842
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 478
selected - selezionate 0
volume - volumi 0
Totale 38.320


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.780 0 0 16 111 163 365 336 244 216 156 76 97
2020/20211.067 130 117 32 66 27 82 25 83 121 224 93 67
2021/20222.188 42 134 187 119 246 80 97 192 159 153 270 509
2022/20232.845 386 455 120 314 344 332 67 295 200 110 147 75
2023/20242.135 66 171 163 116 146 541 203 185 48 197 170 129
2024/2025481 154 151 176 0 0 0 0 0 0 0 0 0
Totale 12.675