The case here reported involves a schizophrenic 19-year-old girl under treatment with clotiapine, which was well tolerated except for a moderate dry mouth. The woman ingested a whole sole (Solea solea), which caused a very rapid death by choking. A complete autopsy was performed 24 h later, as well as histological and toxicological analysis. At autopsy, the sole was wedged in the esophagus causing a choking ab extrinseco. The fish had a length of 18 cm and a maximum width of 6 cm, weighing 188.7 g. Toxicological analysis detected 0.57 mg/L of clotiapine in blood, which falls within the therapeutic range. The peculiarity of this case is represented by two factors: one is the choking by fish and the second was the adverse affect caused by clotiapine, which induced a condition of dry mouth making the act of swallowing even more difficult, thereby contributing to a very rapid mechanical asphyxia and the death of the young woman.

A very unusual accidental mechanical asphyxia of choking with a whole solea solea / Busardo', FRANCESCO PAOLO; Mannocchi, Giulio; Pugnetti, Paola; Santurro, Alessandro; Maggiordomo, Aldo; Zaami, Simona. - In: JOURNAL OF FORENSIC SCIENCES. - ISSN 0022-1198. - ELETTRONICO. - 62:2(2017), pp. 511-514. [10.1111/1556-4029.13261]

A very unusual accidental mechanical asphyxia of choking with a whole solea solea

BUSARDO', FRANCESCO PAOLO;MANNOCCHI, Giulio;Santurro, Alessandro;ZAAMI, Simona
2017

Abstract

The case here reported involves a schizophrenic 19-year-old girl under treatment with clotiapine, which was well tolerated except for a moderate dry mouth. The woman ingested a whole sole (Solea solea), which caused a very rapid death by choking. A complete autopsy was performed 24 h later, as well as histological and toxicological analysis. At autopsy, the sole was wedged in the esophagus causing a choking ab extrinseco. The fish had a length of 18 cm and a maximum width of 6 cm, weighing 188.7 g. Toxicological analysis detected 0.57 mg/L of clotiapine in blood, which falls within the therapeutic range. The peculiarity of this case is represented by two factors: one is the choking by fish and the second was the adverse affect caused by clotiapine, which induced a condition of dry mouth making the act of swallowing even more difficult, thereby contributing to a very rapid mechanical asphyxia and the death of the young woman.
2017
adverse effects; clotiapine; fatal case; fish choking; forensic science; mechanical asphyxia; 2734; genetics
01 Pubblicazione su rivista::01i Case report
A very unusual accidental mechanical asphyxia of choking with a whole solea solea / Busardo', FRANCESCO PAOLO; Mannocchi, Giulio; Pugnetti, Paola; Santurro, Alessandro; Maggiordomo, Aldo; Zaami, Simona. - In: JOURNAL OF FORENSIC SCIENCES. - ISSN 0022-1198. - ELETTRONICO. - 62:2(2017), pp. 511-514. [10.1111/1556-4029.13261]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/968857
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