Oxygen-Ozone treatment in bisphosphonate related osteonecrosis of the jaw: a case report

BRONJ is characterizes by a wide range bone exposure with a great deal of variables. The lesions are often anticipated by inflammation of the mucosa together with reddening and/or pain. The bone exposure is often associated with bacterial infection and abscess. The most common complications are: nerves involvement, abscesses in the nasal cavity or in paranasal sinuses and pathological bones fractures. Considering the pathogenesis and the clinical outcome, the therapeutic strategy is oriented to face the infective complications (antibiotic, antiseptic, antifungal) and to remove the necrotic bone (minimally-invasive surgery). Bio-stimulation of involved tissue is also recommended.