The use of β-blockers represents a milestone in the treatment of heart failure with reduced ejection fraction (HFrEF). Few studies have compared β-blockers in HFrEF, and there is little data on the effects of different doses. The present study aimed to investigate in a large database of HFrEF patients (MECKI score database) the association of β-blocker treatment with a composite outcome of cardiovascular death, urgent heart transplantation or left ventricular assist device implantation, addressing the role of β-selectivity and dosage regimens.
Prognostic role of β-blocker selectivity and dosage regimens in heart failure patients. Insights from the MECKI score database / Paolillo, S., Mapelli, M., Bonomi, A., Corrà, U., Piepoli, M., Veglia, F., Salvioni, E., Gentile, P., Lagioia, R., Metra, M., Limongelli, G., Sinagra, G., Cattadori, G., Scardovi, A.B., Carubelli, V., Scrutino, D., Badagliacca, R., Raimondo, R., Emdin, M., Magri', D., et al.. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - 19:7(2017), pp. 904-914. [10.1002/ejhf.775]
Prognostic role of β-blocker selectivity and dosage regimens in heart failure patients. Insights from the MECKI score database
BADAGLIACCA, ROBERTO;MAGRI', DAMIANO;SCIOMER, Susanna;
2017
Abstract
The use of β-blockers represents a milestone in the treatment of heart failure with reduced ejection fraction (HFrEF). Few studies have compared β-blockers in HFrEF, and there is little data on the effects of different doses. The present study aimed to investigate in a large database of HFrEF patients (MECKI score database) the association of β-blocker treatment with a composite outcome of cardiovascular death, urgent heart transplantation or left ventricular assist device implantation, addressing the role of β-selectivity and dosage regimens.| File | Dimensione | Formato | |
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