Anomalous diffusion (AD) stretched-exponential g-imaging model, was applied to investigate a fixed mouse spinal cord by using gradient strength varying PGSTE sequence at 9.4T. To highlight the new additional information provided by AD approach, we compared AD images with results obtained by using conventional DTI, relaxometry and histological data. Mean g (Mg), g-anisotropy (Ag), gpar and gortho are able to detect microstructural information of white matter (WM) in spinal cord more specific and complementary to those provided by DTI. Specifically, the correlation between Ag and myelin fraction is in agreement with the anisotropic rearrangement of myelin along WM fibers.
Anomalous diffusion stretched exponential gamma-imaging model provides new information on spinal cord microstructure - e-poster #2907 / Caporale, Alessandra; Palombo, Marco; Capuani, Silvia. - In: ISMRM 23rd meeting - Proceedings educational syllabus. - ELETTRONICO. - (2015). (Intervento presentato al convegno International Society for Magnetic Resonance in Medicine - 23rd meeting tenutosi a Toronto, Ontario, Canada nel 30/05/2015 - 05/06/2015).
Anomalous diffusion stretched exponential gamma-imaging model provides new information on spinal cord microstructure - e-poster #2907
CAPORALE, ALESSANDRA;CAPUANI, Silvia
2015
Abstract
Anomalous diffusion (AD) stretched-exponential g-imaging model, was applied to investigate a fixed mouse spinal cord by using gradient strength varying PGSTE sequence at 9.4T. To highlight the new additional information provided by AD approach, we compared AD images with results obtained by using conventional DTI, relaxometry and histological data. Mean g (Mg), g-anisotropy (Ag), gpar and gortho are able to detect microstructural information of white matter (WM) in spinal cord more specific and complementary to those provided by DTI. Specifically, the correlation between Ag and myelin fraction is in agreement with the anisotropic rearrangement of myelin along WM fibers.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
