The development of the β− based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for brain tumours. To validate the technique, prototypes of the intraoperative β− probe have been developed. This paper discusses the design details of one of the prototypes and its tests performed in laboratory. In such tests particular care has to be taken to reproduce the surgical field conditions. The tests showed that the prototype under study has 70% efficiency on electrons with an energy threshold at 540 keV, a point-like resolution of 2.8±0.1 mm, and a sensitivity to photons lower than 1%. The tests also demonstrated, with an innovative technique to produce specific phantoms, that 0.5 ml residuals can be safely identified in 1 s with tumor-non-tumor ratio equal to 10.

An Intraoperative β- Detecting Probe for Radio-Guided Surgery in Tumour Resection / Russomando, Andrea; Bellini, Fabio; Bocci, Valerio; Collamati, Francesco; DE LUCIA, Erika; Faccini, Riccardo; Marafini, Michela; Mattei, Ilaria; Chiodi, Giacomo; Patera, Vincenzo; Recchia, Luigi; Sarti, Alessio; Sciubba, Adalberto; SOLFAROLI CAMILLOCCI, Elena; Paramatti, Riccardo; Voena, Cecilia; Donnarumma, Raffaella; MANCINI TERRACCIANO, Carlo; Morganti, Silvio. - In: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. - ISSN 0018-9499. - STAMPA. - 63:5(2016), pp. 2533-2539. [10.1109/TNS.2016.2600266]

An Intraoperative β- Detecting Probe for Radio-Guided Surgery in Tumour Resection

RUSSOMANDO, ANDREA;BELLINI, Fabio;COLLAMATI, FRANCESCO;DE LUCIA, Erika;FACCINI, Riccardo;PATERA, Vincenzo;SARTI, ALESSIO;SCIUBBA, Adalberto;SOLFAROLI CAMILLOCCI, ELENA;PARAMATTI, Riccardo;VOENA, Cecilia;DONNARUMMA, RAFFAELLA;MANCINI TERRACCIANO, CARLO;
2016

Abstract

The development of the β− based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for brain tumours. To validate the technique, prototypes of the intraoperative β− probe have been developed. This paper discusses the design details of one of the prototypes and its tests performed in laboratory. In such tests particular care has to be taken to reproduce the surgical field conditions. The tests showed that the prototype under study has 70% efficiency on electrons with an energy threshold at 540 keV, a point-like resolution of 2.8±0.1 mm, and a sensitivity to photons lower than 1%. The tests also demonstrated, with an innovative technique to produce specific phantoms, that 0.5 ml residuals can be safely identified in 1 s with tumor-non-tumor ratio equal to 10.
Beta probe; cancer detection; phantoms; radio-guided surgery; simulation; surgical instruments; Nuclear and High Energy Physics; Nuclear Energy and Engineering; Electrical and Electronic Engineering
01 Pubblicazione su rivista::01a Articolo in rivista
An Intraoperative β- Detecting Probe for Radio-Guided Surgery in Tumour Resection / Russomando, Andrea; Bellini, Fabio; Bocci, Valerio; Collamati, Francesco; DE LUCIA, Erika; Faccini, Riccardo; Marafini, Michela; Mattei, Ilaria; Chiodi, Giacomo; Patera, Vincenzo; Recchia, Luigi; Sarti, Alessio; Sciubba, Adalberto; SOLFAROLI CAMILLOCCI, Elena; Paramatti, Riccardo; Voena, Cecilia; Donnarumma, Raffaella; MANCINI TERRACCIANO, Carlo; Morganti, Silvio. - In: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. - ISSN 0018-9499. - STAMPA. - 63:5(2016), pp. 2533-2539. [10.1109/TNS.2016.2600266]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/905390
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