Background: While psychiatry literature has shown renewed interest in fine psychopathological investigation to the pre-psychotic phase of schizophrenia, very few studies have been focus the attention to the potentially predictive value of the clinicians impression. Objective and Methods: The objective of this study was to evaluate the validity of a standardized questionnaire on clinical impression. A three-year cohort study (N = 240) within the early detection project Liberiamo il futuro was designed to identify high-risk subjects for developing a psychosis among a help-seeking population. From January 2012, all subjects between 12 and 35 years seeking assistance at six community mental health services in the Lazio Region were enrolled in the study. To identify potential ultra-high risk (UHR) patients the Prodromal Questionnaire (PQ 92-items) and a Clinical impression assessment of pre-psychotic phase of schizophrenia (CIAPPS) questionnaire were used. The CIAPPS is a short standardized questionnaire (10 items) that was developed by a panel of expert psychiatrists. UHR subjects were established by SIPS. Results: Out of 114 subjects, 28 were classified as UHR+. There was a sensitivity of 71.4%, specificity of 86.9%, positive predictive value (PPV) of 37.7% and negative predictive value (NPV) of 86.9% for CIAPPS, while there was a sensitivity of 53.6%, specificity of 80.0%, PPV of 30.6% and NPV of 80.0% using the PQ. Conclusion: Our study suggests that clinical impression questionnaire may be consider
The validity of a clinical impression questionnarie to identify UHR patients / J. Fortes Lindau, M. Brandizzi; Masillo, Alice; Kotzalidis, Giorgio; Fortes, C.; Mastroeni, S.; Solfanelli, Andrea; Curto, Martina; Leccisi, D.; Girardi, Paolo. - In: EARLY INTERVENTION IN PSYCHIATRY. - ISSN 1751-7885. - STAMPA. - vol. 8, supp. 1:(2014), pp. 132-132. (Intervento presentato al convegno 9th Interantional Conference on Early Psychosis tenutosi a Tokyo nel 17/19 novembre 2014).
The validity of a clinical impression questionnarie to identify UHR patients
MASILLO, ALICE;KOTZALIDIS, GIORGIO;SOLFANELLI, ANDREA;CURTO, MARTINA;GIRARDI, Paolo
2014
Abstract
Background: While psychiatry literature has shown renewed interest in fine psychopathological investigation to the pre-psychotic phase of schizophrenia, very few studies have been focus the attention to the potentially predictive value of the clinicians impression. Objective and Methods: The objective of this study was to evaluate the validity of a standardized questionnaire on clinical impression. A three-year cohort study (N = 240) within the early detection project Liberiamo il futuro was designed to identify high-risk subjects for developing a psychosis among a help-seeking population. From January 2012, all subjects between 12 and 35 years seeking assistance at six community mental health services in the Lazio Region were enrolled in the study. To identify potential ultra-high risk (UHR) patients the Prodromal Questionnaire (PQ 92-items) and a Clinical impression assessment of pre-psychotic phase of schizophrenia (CIAPPS) questionnaire were used. The CIAPPS is a short standardized questionnaire (10 items) that was developed by a panel of expert psychiatrists. UHR subjects were established by SIPS. Results: Out of 114 subjects, 28 were classified as UHR+. There was a sensitivity of 71.4%, specificity of 86.9%, positive predictive value (PPV) of 37.7% and negative predictive value (NPV) of 86.9% for CIAPPS, while there was a sensitivity of 53.6%, specificity of 80.0%, PPV of 30.6% and NPV of 80.0% using the PQ. Conclusion: Our study suggests that clinical impression questionnaire may be considerI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
