Glaucomatous optic neuropathy is the most commonly acquired optic neuropathy encountered in clinical practice. It is the second leading cause of blindness globally, after cataracts, but it presents a greater public health challenge than cataracts, because the blindness it causes is irreversible. It has pathogenesis still largely unknown and no established cure. Alterations in serum antibody profiles, upregulation, and downregulation have been described, but it still remains elusive if the autoantibodies seen in glaucoma are an epiphenomenon or causative. Hypertension, diabetes, and hearing disorders also are associated. This review is a glaucoma update with focus about the recent advances in the last 15 years.

Glaucoma: recent advances in the involvement of autoimmunity / Rizzo, MARIA IDA; Greco, Antonio; DE VIRGILIO, Armando; Gallo, Andrea; Taverniti, Luciano; Fusconi, Massimo; Conte, Michela; Pagliuca, Giulio; Turchetta, Rosaria; DE VINCENTIIS, Marco. - In: IMMUNOLOGIC RESEARCH. - ISSN 0257-277X. - 65:1(2017), pp. 207-217. [10.1007/s12026-016-8837-3]

Glaucoma: recent advances in the involvement of autoimmunity

RIZZO, MARIA IDA
Primo
;
GRECO, Antonio
Secondo
;
DE VIRGILIO, ARMANDO
;
GALLO, Andrea;TAVERNITI, Luciano;FUSCONI, Massimo;CONTE, MICHELA;PAGLIUCA, GIULIO;TURCHETTA, Rosaria
Penultimo
;
DE VINCENTIIS, Marco
Ultimo
2017

Abstract

Glaucomatous optic neuropathy is the most commonly acquired optic neuropathy encountered in clinical practice. It is the second leading cause of blindness globally, after cataracts, but it presents a greater public health challenge than cataracts, because the blindness it causes is irreversible. It has pathogenesis still largely unknown and no established cure. Alterations in serum antibody profiles, upregulation, and downregulation have been described, but it still remains elusive if the autoantibodies seen in glaucoma are an epiphenomenon or causative. Hypertension, diabetes, and hearing disorders also are associated. This review is a glaucoma update with focus about the recent advances in the last 15 years.
2017
angle-closure glaucoma; autoimmunity; glaucoma; glaucomatous optic neuropathy; normal-tension glaucoma; open-angle glaucoma; immunology
01 Pubblicazione su rivista::01a Articolo in rivista
Glaucoma: recent advances in the involvement of autoimmunity / Rizzo, MARIA IDA; Greco, Antonio; DE VIRGILIO, Armando; Gallo, Andrea; Taverniti, Luciano; Fusconi, Massimo; Conte, Michela; Pagliuca, Giulio; Turchetta, Rosaria; DE VINCENTIIS, Marco. - In: IMMUNOLOGIC RESEARCH. - ISSN 0257-277X. - 65:1(2017), pp. 207-217. [10.1007/s12026-016-8837-3]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/889696
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