BACKGROUND: The occurrence of radiological mediastinal lymphadenopathy as the only evidence of tumor recurrence of cervical carcinoma is very rare. We report on such a case with stenosis of the esophagus. CASE REPORT: A 36-year-old Caucasian woman, without any relevant history of gynecological cancer, underwent a trans-vaginal ultrasound with evidence of any cervical lesion locally extended. After histologically-proven diagnosis of squamous cell carcinoma of the cervix uterine, the patient was treated by neoadjuvant chemoradiation, followed by total abdominal hysterectomy with bilateral salpingoophorectomy. A subsequent close follow-up was negative for recurrence of disease until December 2008, two years after diagnosis. At that period, the patient experienced cough and severe dysphagia and for this reason she underwent several examinations including esophagogastroduodenoscopy, whole-body computed tomographic scan and bronchoscopy with transbronchial needle aspiration. Histology led to diagnosis of recurrence of cervical cancer, HPV31-positive, in multiple mediastinal lymphnodes, with infiltration of the esophageal mucosa. CONCLUSION: Mediastinal lymphade-nopathy in patients with a history of cervical carcinoma should be suspicious of metastatic disease, even if there is no radiological evidence of distant metastases.

Esophageal stenosis: a differential diagnosis between esophageal cancer and metastasis from other neoplasia / Paris, Ida; Prelaj, Arsela; Onesti, CONCETTA ELISA; Baldoni, Alessandra; Giovagnoli, Maria Rosaria; Bassanelli, Maria; Lauro, Salvatore; Marchetti, Paolo. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - STAMPA. - 34:1(2014), pp. 363-366.

Esophageal stenosis: a differential diagnosis between esophageal cancer and metastasis from other neoplasia

PRELAJ, ARSELA;ONESTI, CONCETTA ELISA;GIOVAGNOLI, Maria Rosaria;BASSANELLI, MARIA;LAURO, Salvatore;MARCHETTI, PAOLO
2014

Abstract

BACKGROUND: The occurrence of radiological mediastinal lymphadenopathy as the only evidence of tumor recurrence of cervical carcinoma is very rare. We report on such a case with stenosis of the esophagus. CASE REPORT: A 36-year-old Caucasian woman, without any relevant history of gynecological cancer, underwent a trans-vaginal ultrasound with evidence of any cervical lesion locally extended. After histologically-proven diagnosis of squamous cell carcinoma of the cervix uterine, the patient was treated by neoadjuvant chemoradiation, followed by total abdominal hysterectomy with bilateral salpingoophorectomy. A subsequent close follow-up was negative for recurrence of disease until December 2008, two years after diagnosis. At that period, the patient experienced cough and severe dysphagia and for this reason she underwent several examinations including esophagogastroduodenoscopy, whole-body computed tomographic scan and bronchoscopy with transbronchial needle aspiration. Histology led to diagnosis of recurrence of cervical cancer, HPV31-positive, in multiple mediastinal lymphnodes, with infiltration of the esophageal mucosa. CONCLUSION: Mediastinal lymphade-nopathy in patients with a history of cervical carcinoma should be suspicious of metastatic disease, even if there is no radiological evidence of distant metastases.
2014
Esophageal stenosis; cervical cancer; mediastinal lymph node; recurrence of cervical carcinoma; Adult; Diagnosis, Differential; Esophageal Neoplasms; Esophageal Stenosis; Female; Humans; Lymphatic Metastasis; Mediastinal Neoplasms; Prognosis
01 Pubblicazione su rivista::01a Articolo in rivista
Esophageal stenosis: a differential diagnosis between esophageal cancer and metastasis from other neoplasia / Paris, Ida; Prelaj, Arsela; Onesti, CONCETTA ELISA; Baldoni, Alessandra; Giovagnoli, Maria Rosaria; Bassanelli, Maria; Lauro, Salvatore; Marchetti, Paolo. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - STAMPA. - 34:1(2014), pp. 363-366.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/872953
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact