Objectives. To review the current knowledge of the aetiology of vestibular neuritis including viral infections, vascular occlusion, and immunomediatedmechanisms and to discuss the pathogenesis with relevance to pharmacotherapy. Systematic ReviewMethodology. Relevant publications on the aetiology and treatment of vestibular neuritis from1909 to 2013were analysed. Results and Conclusions. Vestibular neuritis is the second most common cause of peripheral vestibular vertigo and is due to a sudden unilateral loss of vestibular function. Vestibular neuronitis is a disorder thought to represent the vestibular-nerve equivalent of sudden sensorineural hearing loss. Histopathological studies of patients who died from unrelated clinical problems have demonstrated degeneration of the superior vestibular nerve.The characteristic signs and symptoms include sudden and prolonged vertigo, the absence of auditory symptoms, and the absence of other neurological symptoms. The aetiology and pathogenesis of the condition remain unknown. Proposed theories of causation include viral infections, vascular occlusion, and immunomediatedmechanisms.Themanagement of vestibular neuritis involves symptomatic treatment with antivertiginous drugs, causal treatment with corticosteroids, and physical therapy. Antiviral agents did not improve the outcomes.

Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? / Greco, Antonio; Macri, GIAN FRANCO; Gallo, Andrea; Fusconi, Massimo; DE VIRGILIO, Armando; Pagliuca, Giulio; Marinelli, Caterina; DE VINCENTIIS, Marco. - In: JOURNAL OF IMMUNOLOGY RESEARCH. - ISSN 2314-7156. - 2014:459048(2014). [10.1155/2014/459048]

Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo?

GRECO, Antonio
Primo
;
MACRI, GIAN FRANCO
Secondo
;
GALLO, Andrea;FUSCONI, Massimo;DE VIRGILIO, ARMANDO;PAGLIUCA, GIULIO;DE VINCENTIIS, Marco
Ultimo
2014

Abstract

Objectives. To review the current knowledge of the aetiology of vestibular neuritis including viral infections, vascular occlusion, and immunomediatedmechanisms and to discuss the pathogenesis with relevance to pharmacotherapy. Systematic ReviewMethodology. Relevant publications on the aetiology and treatment of vestibular neuritis from1909 to 2013were analysed. Results and Conclusions. Vestibular neuritis is the second most common cause of peripheral vestibular vertigo and is due to a sudden unilateral loss of vestibular function. Vestibular neuronitis is a disorder thought to represent the vestibular-nerve equivalent of sudden sensorineural hearing loss. Histopathological studies of patients who died from unrelated clinical problems have demonstrated degeneration of the superior vestibular nerve.The characteristic signs and symptoms include sudden and prolonged vertigo, the absence of auditory symptoms, and the absence of other neurological symptoms. The aetiology and pathogenesis of the condition remain unknown. Proposed theories of causation include viral infections, vascular occlusion, and immunomediatedmechanisms.Themanagement of vestibular neuritis involves symptomatic treatment with antivertiginous drugs, causal treatment with corticosteroids, and physical therapy. Antiviral agents did not improve the outcomes.
2014
animals; humans; infection; vertigo; vestibular nerve; vestibular neuronitis; medicine
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? / Greco, Antonio; Macri, GIAN FRANCO; Gallo, Andrea; Fusconi, Massimo; DE VIRGILIO, Armando; Pagliuca, Giulio; Marinelli, Caterina; DE VINCENTIIS, Marco. - In: JOURNAL OF IMMUNOLOGY RESEARCH. - ISSN 2314-7156. - 2014:459048(2014). [10.1155/2014/459048]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/835509
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