Background: Peritoneal surface malignancies (PSMs) are usually staged using Sugarbaker's Peritoneal Cancer Index (PCI) and completeness of cytoreduction score (CC-s). Although these staging tools are essential for selecting patients and evaluating outcome after cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC), both scoring models lack some anatomic information, thus making staging laborious and unreliable. Maintaining Sugarbaker's original concepts, we therefore developed a computerized digital tool, including a new anatomic scheme for calculating PCI and CC-s corresponding closely to patients' real anatomy. Our new anatomic model belongs in a web-based application known as the PSM Staging System, which contains essential clinical and pathological data for the various PSMs currently treated. Methods: The new digital tool for staging PSM runs on a personal computer or tablet and comprises male and female colored anatomic models for the 13 endoabdominal regions, with borders defined according to real anatomic landmarks. A drag-and-drop tool allows users to compute the PCI and CC-s, making it easier to localize and quantify disease at diagnosis and throughout treatment, and residual disease after CRS. Conclusions: Once tested online by registered users, our computerized application should provide a modern, shareable, comprehensive, user-friendly PSM staging system. Its anatomic features, along with the drag-and-drop tool, promise to make it easier to compare preoperative and postoperative PCIs, thus improving the criteria for selecting patients to undergo CRS plus HIPEC. By specifying the size, site, and number of residual lesions after CRS plus HIPEC, our digital tool should help stratify patients into outcome classes.

Computerized system for staging peritoneal surface malignancies / Sammartino, Paolo; Biacchi, Daniele; Cornali, Tommaso; Accarpio, Fabio; Sibio, Simone; Luraschi, Bernard Stephane C.; Impagnatiello, Alessio; Di Giorgio, Angelo. - In: ANNALS OF SURGICAL ONCOLOGY. - ISSN 1068-9265. - ELETTRONICO. - 23:5(2016), pp. 1454-1460. [10.1245/s10434-015-4966-5]

Computerized system for staging peritoneal surface malignancies

SAMMARTINO, Paolo;BIACCHI, DANIELE;CORNALI, TOMMASO;ACCARPIO, Fabio;SIBIO, SIMONE;LURASCHI, Bernard Stephane C.;IMPAGNATIELLO, ALESSIO;DI GIORGIO, Angelo
2016

Abstract

Background: Peritoneal surface malignancies (PSMs) are usually staged using Sugarbaker's Peritoneal Cancer Index (PCI) and completeness of cytoreduction score (CC-s). Although these staging tools are essential for selecting patients and evaluating outcome after cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC), both scoring models lack some anatomic information, thus making staging laborious and unreliable. Maintaining Sugarbaker's original concepts, we therefore developed a computerized digital tool, including a new anatomic scheme for calculating PCI and CC-s corresponding closely to patients' real anatomy. Our new anatomic model belongs in a web-based application known as the PSM Staging System, which contains essential clinical and pathological data for the various PSMs currently treated. Methods: The new digital tool for staging PSM runs on a personal computer or tablet and comprises male and female colored anatomic models for the 13 endoabdominal regions, with borders defined according to real anatomic landmarks. A drag-and-drop tool allows users to compute the PCI and CC-s, making it easier to localize and quantify disease at diagnosis and throughout treatment, and residual disease after CRS. Conclusions: Once tested online by registered users, our computerized application should provide a modern, shareable, comprehensive, user-friendly PSM staging system. Its anatomic features, along with the drag-and-drop tool, promise to make it easier to compare preoperative and postoperative PCIs, thus improving the criteria for selecting patients to undergo CRS plus HIPEC. By specifying the size, site, and number of residual lesions after CRS plus HIPEC, our digital tool should help stratify patients into outcome classes.
2016
Surgery; Oncology, peritoneal carcinomatosis
01 Pubblicazione su rivista::01a Articolo in rivista
Computerized system for staging peritoneal surface malignancies / Sammartino, Paolo; Biacchi, Daniele; Cornali, Tommaso; Accarpio, Fabio; Sibio, Simone; Luraschi, Bernard Stephane C.; Impagnatiello, Alessio; Di Giorgio, Angelo. - In: ANNALS OF SURGICAL ONCOLOGY. - ISSN 1068-9265. - ELETTRONICO. - 23:5(2016), pp. 1454-1460. [10.1245/s10434-015-4966-5]
File allegati a questo prodotto
File Dimensione Formato  
Sammartino_ Computerized-system_2016.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 3.33 MB
Formato Adobe PDF
3.33 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/833182
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 4
social impact