Obstructive sleep apnea syndrome (OSAS) has emerged as a risk factor for cardiovascular disease. A prothrombotic state may affect coagulation and participate in the atherosclerotic process in subjects with OSAS. These alterations in coagulation seem to involve the plasminogen activation system. We evaluated the imbalances of the plasminogen activation system related to OSAS, and we assessed the effects of CPAP on the plasminogen activation system.

The plasminogen system and transforming growth factor-β in subjects with obstructive sleep pnea syndrome: effects of CPAP treatment / Steffanina, Alessia; Proietti, Lidia; Antonaglia, Caterina; Palange, Paolo; Angelici, Elena; Canipari, Rita. - In: RESPIRATORY CARE. - ISSN 0020-1324. - STAMPA. - 63:11(2015), pp. 1643-1651. [10.4187/respcare.03571]

The plasminogen system and transforming growth factor-β in subjects with obstructive sleep pnea syndrome: effects of CPAP treatment

STEFFANINA, ALESSIA;PROIETTI, LIDIA;ANTONAGLIA, CATERINA;PALANGE, Paolo;ANGELICI, Elena;CANIPARI, Rita
2015

Abstract

Obstructive sleep apnea syndrome (OSAS) has emerged as a risk factor for cardiovascular disease. A prothrombotic state may affect coagulation and participate in the atherosclerotic process in subjects with OSAS. These alterations in coagulation seem to involve the plasminogen activation system. We evaluated the imbalances of the plasminogen activation system related to OSAS, and we assessed the effects of CPAP on the plasminogen activation system.
CPAP; PAI-1; TGF-β; sleep apnea; tPA; uPA
01 Pubblicazione su rivista::01a Articolo in rivista
The plasminogen system and transforming growth factor-β in subjects with obstructive sleep pnea syndrome: effects of CPAP treatment / Steffanina, Alessia; Proietti, Lidia; Antonaglia, Caterina; Palange, Paolo; Angelici, Elena; Canipari, Rita. - In: RESPIRATORY CARE. - ISSN 0020-1324. - STAMPA. - 63:11(2015), pp. 1643-1651. [10.4187/respcare.03571]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/814855
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