Severe obstructive sleep apnea syndrome and erectile dysfunction: a prospective randomised study to compare sildenafil versus nasal continuous positive airway pressure

A high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS) has been reported. In this prospective randomized controlled trial, we investigated 82 men with ED consecutively who were referred to the outpatient clinic for sleep disorders and had severe OSAS (AHI > 30 events/h) without any other comorbidities as a possible cause of ED. The aim of this study was to evaluate and compare the efficacy of sildenafil versus continuous positive airway pressure (CPAP) in men with ED and severe OSAS.