Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection. Here we report a case study providing evidence that ganciclovir, administered as valganciclovir, reaches the infant's cerebrospinal fluid when used at the currently recommended dose for congenital cytomegalovirus infection.
Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection / Fabio, Natale; Bizzarri, Bianca; Cardi, Veronica; Gaeta, Aurelia; Paola, Villani; Giuseppina, Liuzzi; DE CURTIS, Mario. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1824-7288. - STAMPA. - 41:1(2015). [10.1186/s13052-015-0132-8]
Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection
BIZZARRI, BIANCA;CARDI, VERONICA;GAETA, Aurelia;DE CURTIS, MARIO
2015
Abstract
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection. Here we report a case study providing evidence that ganciclovir, administered as valganciclovir, reaches the infant's cerebrospinal fluid when used at the currently recommended dose for congenital cytomegalovirus infection.| File | Dimensione | Formato | |
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