Herpes viruses are ubiquitous pathogens associated with high morbidity and mortality in immunocompromised individuals. Following symptomatic primary infection, all herpes viruses maintain a state of lifelong asymptomatic latent persistence in the host with sporadic symptomatic reactivation. The persistence of these viruses has been described in several tissues including stomach, intestine and colon Viral reactivation from such reservoirs may induce disease in immunocompromised individuals. We evaluated the presence of herpes viruses (EBV, HHV6 and CMV) in gastric, duodenal and colon biopsies from HIV-positive patients. Viral DNA was quantified with Taqman Real-Time PCR
Herpes viruses are ubiquitous pathogens associated with high morbidity and mortality in immunocompromised individuals. Following symptomatic primary infection, all herpes viruses maintain a state of lifelong asymptomatic latent persistence in the host with sporadic symptomatic reactivation. The persistence of these viruses has been described in several tissues including stomach, intestine and colon Viral reactivation from such reservoirs may induce disease in immunocompromised individuals. We evaluated the presence of herpes viruses (EBV, HHV6 and CMV) in gastric, duodenal and colon biopsies from HIV-positive patients. Viral DNA was quantified with Taqman Real-Time PCR
Quantification of EBV, HHV6 and CMV DNA in gastrointestinal biopsies from HIV-1 positive patients / Maida, Paola; Falasca, Francesca; Gaeta, Aurelia; Donato, Giuseppe; Montagna, C; Fantauzzi, Alessandra; Nazzari, Cristina; Mezzaroma, Ivano; Antonelli, Guido; Turriziani, Ombretta. - ELETTRONICO. - (2012). (Intervento presentato al convegno ICAR 2012 tenutosi a Napoli, Italia nel 10-12 Giugno 2012).
Quantification of EBV, HHV6 and CMV DNA in gastrointestinal biopsies from HIV-1 positive patients.
MAIDA, PAOLA;FALASCA, FRANCESCA;GAETA, Aurelia;DONATO, Giuseppe;FANTAUZZI, Alessandra;NAZZARI, Cristina;MEZZAROMA, Ivano;ANTONELLI, Guido;TURRIZIANI, Ombretta
2012
Abstract
Herpes viruses are ubiquitous pathogens associated with high morbidity and mortality in immunocompromised individuals. Following symptomatic primary infection, all herpes viruses maintain a state of lifelong asymptomatic latent persistence in the host with sporadic symptomatic reactivation. The persistence of these viruses has been described in several tissues including stomach, intestine and colon Viral reactivation from such reservoirs may induce disease in immunocompromised individuals. We evaluated the presence of herpes viruses (EBV, HHV6 and CMV) in gastric, duodenal and colon biopsies from HIV-positive patients. Viral DNA was quantified with Taqman Real-Time PCRI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
