Finding new ways to fight cancer is essential to increase the patients life expectancy. This paper reports the latest results of the project CHIRONE finalized to increase the potential of the Radio Guided Surgery through the use of β- emitting radio-tracers and β- probes. This innovation could overcome the present main limiting factor represented by a diffuse background due to the high penetration power of the gamma radiation used. We created a prototype of β- probe and in this paper we report measures of photon efficiency, acquired with commercial photons sources. Then we estimated the signal and background rates in realistic cases of meningioma through a simulation. The device is able to detect residuals of 0.1 ml in 1 s with an administered activity less than 3 MBq/kg.

An innovative radio-guided surgery technique for complete resection of tumors / Russomando, Andrea; Collamati, Francesco; Bellini, Fabio; V., Bocci; Erika De, Lucia; Faccini, Riccardo; P. M., Frallicciardi; M., Marafini; I., Mattei; S., Morganti; Patera, Vincenzo; Piersanti, Luca; Davide, Pinci; L., Recchia; Senzacqua, Martina; Sarti, Alessio; Sciubba, Adalberto; SOLFAROLI CAMILLOCCI, Elena; Voena, Cecilia. - In: JOURNAL OF PHYSICS. CONFERENCE SERIES. - ISSN 1742-6588. - 566:1(2014), p. 012020. ((Intervento presentato al convegno 5th Young Researcher Meeting, YRM 2014 nel 14 July 2014 through 15 July 2014 [10.1088/1742-6596/566/1/012020].

An innovative radio-guided surgery technique for complete resection of tumors

RUSSOMANDO, ANDREA;COLLAMATI, FRANCESCO;BELLINI, Fabio;FACCINI, Riccardo;PATERA, Vincenzo;PIERSANTI, LUCA;SENZACQUA, MARTINA;SARTI, ALESSIO;SCIUBBA, Adalberto;SOLFAROLI CAMILLOCCI, ELENA;VOENA, Cecilia
2014

Abstract

Finding new ways to fight cancer is essential to increase the patients life expectancy. This paper reports the latest results of the project CHIRONE finalized to increase the potential of the Radio Guided Surgery through the use of β- emitting radio-tracers and β- probes. This innovation could overcome the present main limiting factor represented by a diffuse background due to the high penetration power of the gamma radiation used. We created a prototype of β- probe and in this paper we report measures of photon efficiency, acquired with commercial photons sources. Then we estimated the signal and background rates in realistic cases of meningioma through a simulation. The device is able to detect residuals of 0.1 ml in 1 s with an administered activity less than 3 MBq/kg.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/654611
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