Background. Infliximab (IFX) has found an increasing application in children with IBD. Because of the risk of immunogenicity, a concomitant therapy with immunosuppressants, like Azathioprine (AZA) is frequently prescribed. However, lack of data of their cumulative effect is an emerging issue, especially in children due to their prolonged exposure. Data on prevalence and clinical significance of infection with Herpesviruses are scanty. When infection occurs, a modification in the therapeutic regimen for IBD is often required
Role of viral infections in children receiving infliximab and immunosuppressive drugs: When to suspect them / A., Morley Fletcher; O., Borrelli; F., Viola; M., Barbato; Gaeta, Aurelia; Nazzari, Cristina; Mancini, Carlo; S., Cucchiara. - 38:(2006), pp. A101-A102. [10.1016/j.dld.2006.07.052]
Role of viral infections in children receiving infliximab and immunosuppressive drugs: When to suspect them
GAETA, Aurelia;NAZZARI, Cristina;MANCINI, Carlo;
2006
Abstract
Background. Infliximab (IFX) has found an increasing application in children with IBD. Because of the risk of immunogenicity, a concomitant therapy with immunosuppressants, like Azathioprine (AZA) is frequently prescribed. However, lack of data of their cumulative effect is an emerging issue, especially in children due to their prolonged exposure. Data on prevalence and clinical significance of infection with Herpesviruses are scanty. When infection occurs, a modification in the therapeutic regimen for IBD is often requiredI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.