Arginine and zinc(II) play an important role in the human physiology. Arginine is a precursor of NO which is a vasodilator and zinc(II) is frequently an enzyme activator having also therapeutic role. The complex formation between zinc(II) and arginine is studied, at 25 °C and in 1.00 mol dm-3 NaCl as ionic medium. The investigation is carried out potentiometrically, by employing cells involving glass and zinc amalgam electrodes, in a large range of reagent concentration. Experimental data can be explained by assuming the formation of mononuclear complexes in zinc(II), but with the participation of hydrogen ions. The formation of the following species with the relative stability constant explains the experimental data: ZnHL (log β1,1,1 = 16.11 ± 0.07), ZnH2L2 (log β1,2,2 = 33.41 ± 0.05), ZnH3L3 (log β1,3,3 = 45.93), ZnH2L3 (log β1,2,3 = 36.04), and ZnHL3(log β1,1,3 = 27.15), where L represents the completely deprotonated arginine. Graphical Abstract [Figure not available: see fulltext.] © 2014 Springer-Verlag Wien.

Complex formation between zinc(II) and arginine in a large range of reagent concentration / Bottari, Emilio Giovanni; Festa, Maria Rosa; Gentile, Lorella. - In: MONATSHEFTE FÜR CHEMIE. - ISSN 0026-9247. - STAMPA. - 145:(2014), pp. 1707-1714. [10.1007/s00706-014-1279-5]

Complex formation between zinc(II) and arginine in a large range of reagent concentration

BOTTARI, Emilio Giovanni;FESTA, Maria Rosa;GENTILE, LORELLA
2014

Abstract

Arginine and zinc(II) play an important role in the human physiology. Arginine is a precursor of NO which is a vasodilator and zinc(II) is frequently an enzyme activator having also therapeutic role. The complex formation between zinc(II) and arginine is studied, at 25 °C and in 1.00 mol dm-3 NaCl as ionic medium. The investigation is carried out potentiometrically, by employing cells involving glass and zinc amalgam electrodes, in a large range of reagent concentration. Experimental data can be explained by assuming the formation of mononuclear complexes in zinc(II), but with the participation of hydrogen ions. The formation of the following species with the relative stability constant explains the experimental data: ZnHL (log β1,1,1 = 16.11 ± 0.07), ZnH2L2 (log β1,2,2 = 33.41 ± 0.05), ZnH3L3 (log β1,3,3 = 45.93), ZnH2L3 (log β1,2,3 = 36.04), and ZnHL3(log β1,1,3 = 27.15), where L represents the completely deprotonated arginine. Graphical Abstract [Figure not available: see fulltext.] © 2014 Springer-Verlag Wien.
zinc(ii)-arginine complexes; stability constants; coordination chemistry; potentiometric measurements; coordination chemistry zinc(ii)–arginine complexes stability constants potentiometric measurements
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Complex formation between zinc(II) and arginine in a large range of reagent concentration / Bottari, Emilio Giovanni; Festa, Maria Rosa; Gentile, Lorella. - In: MONATSHEFTE FÜR CHEMIE. - ISSN 0026-9247. - STAMPA. - 145:(2014), pp. 1707-1714. [10.1007/s00706-014-1279-5]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/615633
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