Various grafts or combination of graft materials have been used in sinus floor augmentations, and human histologic reports on their performance are available, although limited in number. Histologic analysis of the regenerated tissues will provide useful information regarding the nature and amount of newly formed bone. Aim of the present study was a histological and histomorphometrical evaluation, in humans, of specimens retrieved from sinuses augmented with The maxillary sinuses were filled with phycogene hydroxyapatite (Algipore®, DENTSPLY-Friadent, Mannheim, Germany), macroporous biphasic calcium phosphate (MBCP®) (Leone, Firenze, Italy), calcium carbonate (Biocoral®, Biocoral®, Leader-Novaxa, Milan, Italy), collagenized porcine cortical/cancellous bone (Apatos Cortical, Tecnoss, Coazze, Turin, Italy), anorganic bovine bone (Geistlich Bio-Oss®, Geistlich, Wohlhusen, Switzerland). In every case, 100% biomaterial was used. A total of 15 patients, undergoing 30 sinus augmentation procedures with 6 biomaterials, participated in this study. A total of 82 bone cores were retrieved and processed for histology after healing period of 6 months. In all biomaterials, many grafted particles were lined and, sometimes, bridged by newly formed bone. Some biomaterials particles appeared to be partially resorbed and substituted by newly formed bone. Histomorphometry showed that, in all biomaterials, newly formed bone and residual grafted material particles represented about 30.0 %. The high interconnecting microporosity allowed, in all the present biomaterials, the ingrowth of newly formed bone and vessels in the pores of the partially resorbed particles. In conclusion, within the limitations of the present study, the data provided support the fact that all these biomaterials can be used, successfully, in sinus augmentation procedures.

A Human Comparative Histological Evaluation, After a 6Months Healing Period, of Different Biomaterials Used in Sinus Lifting.

FRATTO, Giovanni;
2012

Abstract

Various grafts or combination of graft materials have been used in sinus floor augmentations, and human histologic reports on their performance are available, although limited in number. Histologic analysis of the regenerated tissues will provide useful information regarding the nature and amount of newly formed bone. Aim of the present study was a histological and histomorphometrical evaluation, in humans, of specimens retrieved from sinuses augmented with The maxillary sinuses were filled with phycogene hydroxyapatite (Algipore®, DENTSPLY-Friadent, Mannheim, Germany), macroporous biphasic calcium phosphate (MBCP®) (Leone, Firenze, Italy), calcium carbonate (Biocoral®, Biocoral®, Leader-Novaxa, Milan, Italy), collagenized porcine cortical/cancellous bone (Apatos Cortical, Tecnoss, Coazze, Turin, Italy), anorganic bovine bone (Geistlich Bio-Oss®, Geistlich, Wohlhusen, Switzerland). In every case, 100% biomaterial was used. A total of 15 patients, undergoing 30 sinus augmentation procedures with 6 biomaterials, participated in this study. A total of 82 bone cores were retrieved and processed for histology after healing period of 6 months. In all biomaterials, many grafted particles were lined and, sometimes, bridged by newly formed bone. Some biomaterials particles appeared to be partially resorbed and substituted by newly formed bone. Histomorphometry showed that, in all biomaterials, newly formed bone and residual grafted material particles represented about 30.0 %. The high interconnecting microporosity allowed, in all the present biomaterials, the ingrowth of newly formed bone and vessels in the pores of the partially resorbed particles. In conclusion, within the limitations of the present study, the data provided support the fact that all these biomaterials can be used, successfully, in sinus augmentation procedures.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/580179
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