The development of a biosensor for high throughput screening of membrane proteins is a major challenge in drug development. Our aim is to chemically functionalize supported nanoporous films and nanosieves, so that they can be used as platforms for membrane protein assays. For this we use pH-responsive poly(methacrylic acid) (PMAA) brushes.
Switching transport through nanopores with pH-responsive polymer brushes for controlled ion permeability / G., Wilhelmina De Groot; Kaori, Sugihara; Santonicola, Mariagabriella; Tomaso, Zambelli; Janos, Voros; G., Julius Vancso. - ELETTRONICO. - (2012). (Intervento presentato al convegno Annual Meeting of the MESA+ Institute for Nanotechnology tenutosi a Enschede, The Netherlands nel September 18, 2012).
Switching transport through nanopores with pH-responsive polymer brushes for controlled ion permeability
SANTONICOLA, MARIAGABRIELLA;
2012
Abstract
The development of a biosensor for high throughput screening of membrane proteins is a major challenge in drug development. Our aim is to chemically functionalize supported nanoporous films and nanosieves, so that they can be used as platforms for membrane protein assays. For this we use pH-responsive poly(methacrylic acid) (PMAA) brushes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
