In this paper I use a case study-the discovery of the chaperon function exerted by proteins in the various steps of the hereditary process-to re-discuss the question whether the nucleic acids are the sole repositories of relevant information as assumed in the information theory of heredity. The evidence I here present of a crucial role for molecular chaperones in the folding of nascent proteins, as well as in DNA duplication, RNA folding and gene control, suggests that the family of proteins acting as molecular chaperones provides information that is complementary to that stored in the nucleic acids, and equally important. A re-evaluation of the role of proteins in the hereditary process is in order away from the gene-centric approach of the information theory of heredity, to which neo-Darwinian evolutionists adhere. © 2012 Springer Science+Business Media B.V.

Proteins, the chaperone function and heredity / Mosini, Valeria. - In: BIOLOGY & PHILOSOPHY. - ISSN 0169-3867. - STAMPA. - 28:1(2013), pp. 53-74. [10.1007/s10539-012-9332-4]

Proteins, the chaperone function and heredity

MOSINI, Valeria
2013

Abstract

In this paper I use a case study-the discovery of the chaperon function exerted by proteins in the various steps of the hereditary process-to re-discuss the question whether the nucleic acids are the sole repositories of relevant information as assumed in the information theory of heredity. The evidence I here present of a crucial role for molecular chaperones in the folding of nascent proteins, as well as in DNA duplication, RNA folding and gene control, suggests that the family of proteins acting as molecular chaperones provides information that is complementary to that stored in the nucleic acids, and equally important. A re-evaluation of the role of proteins in the hereditary process is in order away from the gene-centric approach of the information theory of heredity, to which neo-Darwinian evolutionists adhere. © 2012 Springer Science+Business Media B.V.
2013
cell biology; genes; heredity; molecular biology; molecular chaperones; neo-darwinian thinking; protein folding
01 Pubblicazione su rivista::01a Articolo in rivista
Proteins, the chaperone function and heredity / Mosini, Valeria. - In: BIOLOGY & PHILOSOPHY. - ISSN 0169-3867. - STAMPA. - 28:1(2013), pp. 53-74. [10.1007/s10539-012-9332-4]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/484577
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