The authors on the base of two cases of Gardner's syndrome recently observed, proceed to a wide review of literature on this subject so as to stress the peculiar aspects of this syndrome, so complex and uncommon. The greatest emphasis is given to the role of genetics as regarding to diagnosis and screening programs, as well as to the more recent acquisitions about diagnosis, therapy and follow up of risk lesions, such as colorectal and duodenal adenomas, as well as of intrabdominal desmoid tumours, which, although not histologically malignant, may often influence prognosis negatively, because of their remarkable local invasiveness and tendency to recurrence.

Gardner syndrome: diagnostic, clinical and genetic questions in the light of 2 case reports / Messinetti, Silvio; DEL PORTO, Giuseppe; Giacomelli, Laura; Gagliarducci, E; Grammatico, Paola; Manno, A; Fabrizio, G; Finizio, R; Pulcini, Angelo; Granai, Av. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 0003-469X. - STAMPA. - 66:4(1995), pp. 497-512.

Gardner syndrome: diagnostic, clinical and genetic questions in the light of 2 case reports.

MESSINETTI, Silvio;DEL PORTO, Giuseppe;GIACOMELLI, Laura;GRAMMATICO, Paola;PULCINI, Angelo;
1995

Abstract

The authors on the base of two cases of Gardner's syndrome recently observed, proceed to a wide review of literature on this subject so as to stress the peculiar aspects of this syndrome, so complex and uncommon. The greatest emphasis is given to the role of genetics as regarding to diagnosis and screening programs, as well as to the more recent acquisitions about diagnosis, therapy and follow up of risk lesions, such as colorectal and duodenal adenomas, as well as of intrabdominal desmoid tumours, which, although not histologically malignant, may often influence prognosis negatively, because of their remarkable local invasiveness and tendency to recurrence.
1995
Gardner's syndrome; adenoma; desmoid tumour; FAP; APe gene.
01 Pubblicazione su rivista::01a Articolo in rivista
Gardner syndrome: diagnostic, clinical and genetic questions in the light of 2 case reports / Messinetti, Silvio; DEL PORTO, Giuseppe; Giacomelli, Laura; Gagliarducci, E; Grammatico, Paola; Manno, A; Fabrizio, G; Finizio, R; Pulcini, Angelo; Granai, Av. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 0003-469X. - STAMPA. - 66:4(1995), pp. 497-512.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/47383
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