Purpose: To quantify the health related quality of life in primary immunodeficiency patients. Materials and Methods: We used generic health status and general psychological health questionnaires to determine the range of issues that needed to be considered in examining the burden of common variable immunodeficiency (CVID). Results: The health status of patients with CVID was lower than that observed in normal subjects. Overall, Role-Physical and General Health scales correlated with a poorer clinical status. Surprisingly, the duration of disease did not influence health status. Being female, older, General Health Questionnaire-positive and alexithymic proved to be major risk factors associated with a poor health status. Patients with chronic lung disease and chronic diarrhea had the lowest values on the Medical Outcome Study, Short Form SF-36 (SF-36) scales. Disease severity perception was associated with the General Health Questionnaire and alexithymia status. Limitations in daily activities as a result of lower physical health were the major problems facing common variable immunodeficiency patients. Conclusion: Our data underlined the importance of conducting a periodical health related quality of life assessment on patients with primary antibody deficiencies and, moreover, stressed the necessity of providing psychological support to at risk patients. © Yonsei University College of Medicine 2012.

Health related quality of life in common variable immunodeficiency / Quinti, Isabella; Cristina Di, Pietro; Martini, Helene; Pesce, ANNA MARIA; Francesca, Lombardi; Maddalena, Baumghartner; Colantuono, Stefania; Milito, Cinzia; Stefano, Tabolli. - In: YONSEI MEDICAL JOURNAL. - ISSN 0513-5796. - STAMPA. - 53:3(2012), pp. 603-610. [10.3349/ymj.2012.53.3.603]

Health related quality of life in common variable immunodeficiency

QUINTI, Isabella;MARTINI, HELENE;PESCE, ANNA MARIA;COLANTUONO, STEFANIA;MILITO, CINZIA;
2012

Abstract

Purpose: To quantify the health related quality of life in primary immunodeficiency patients. Materials and Methods: We used generic health status and general psychological health questionnaires to determine the range of issues that needed to be considered in examining the burden of common variable immunodeficiency (CVID). Results: The health status of patients with CVID was lower than that observed in normal subjects. Overall, Role-Physical and General Health scales correlated with a poorer clinical status. Surprisingly, the duration of disease did not influence health status. Being female, older, General Health Questionnaire-positive and alexithymic proved to be major risk factors associated with a poor health status. Patients with chronic lung disease and chronic diarrhea had the lowest values on the Medical Outcome Study, Short Form SF-36 (SF-36) scales. Disease severity perception was associated with the General Health Questionnaire and alexithymia status. Limitations in daily activities as a result of lower physical health were the major problems facing common variable immunodeficiency patients. Conclusion: Our data underlined the importance of conducting a periodical health related quality of life assessment on patients with primary antibody deficiencies and, moreover, stressed the necessity of providing psychological support to at risk patients. © Yonsei University College of Medicine 2012.
sf-36; health related quality of life; common variable immunodeficiency; general health questionnaire-12; ghq-12
01 Pubblicazione su rivista::01a Articolo in rivista
Health related quality of life in common variable immunodeficiency / Quinti, Isabella; Cristina Di, Pietro; Martini, Helene; Pesce, ANNA MARIA; Francesca, Lombardi; Maddalena, Baumghartner; Colantuono, Stefania; Milito, Cinzia; Stefano, Tabolli. - In: YONSEI MEDICAL JOURNAL. - ISSN 0513-5796. - STAMPA. - 53:3(2012), pp. 603-610. [10.3349/ymj.2012.53.3.603]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/442690
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