Detection of serological markersfor Chlamydia trachomatis infection: comparison between two groups of women

The aim of our work has been to study two groups of women (261 asymptomatic women without genital symptoms and 110 attending a Gynaecologic Clinic for genital infections) in order to evaluate the presence of Chlamydia for each group. Then we determined if the presence of serological markers for this infection such as Antibody to Chsp-60 (Ab-Chsp60) or the detection of IgG, IgA and IgM would be different in these two groups of population and consequently if they could be a sensitive screening marker for the course of C.t.infection. In such a way, we would be able to screen the population at high risk for PID (Pelvic Inflammatory Disease) and sterility. In fact if the correlation between high levels of serological markers and serious sequelae following the infection may be demonstrated, women resulted positive at these tests could be identified and appropriately treated.