Cholangiocarcinoma (CCA) is a malignant tumour that arises from biliary epithelium at any portion of the biliary tree. CCA is currently classified as intra-hepatic or extra-hepatic CCA (EH-CCA). Recent evidences suggest that intra-hepatic CCA (IH-CCA) and EH-CCA are biologically different cancers, giving further support to a number of recent epidemiological studies showing large differences in terms of incidence, mortality and risk factors. The purpose of this manuscript is to review recent literature dealing with the descriptive epidemiology and risk factors of CCA with a special effort to compare IH- with EH-CCA.
Intra-hepatic and extra-hepatic cholangiocarcinoma: New insight into epidemiology and risk factors / Cardinale, Vincenzo; Semeraro, Rossella; Torrice, A.; Gatto, M.; Napoli, C.; Bragazzi, MARIA CONSIGLIA; Gentile, Raffaele; Alvaro, Domenico. - In: WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY. - ISSN 1948-5204. - 2:11(2010), pp. 407-416. [10.4251/wjgo.v2.i11.407]
Intra-hepatic and extra-hepatic cholangiocarcinoma: New insight into epidemiology and risk factors.
Vincenzo Cardinale;SEMERARO, ROSSELLA;BRAGAZZI, MARIA CONSIGLIA;GENTILE, Raffaele;ALVARO, Domenico
2010
Abstract
Cholangiocarcinoma (CCA) is a malignant tumour that arises from biliary epithelium at any portion of the biliary tree. CCA is currently classified as intra-hepatic or extra-hepatic CCA (EH-CCA). Recent evidences suggest that intra-hepatic CCA (IH-CCA) and EH-CCA are biologically different cancers, giving further support to a number of recent epidemiological studies showing large differences in terms of incidence, mortality and risk factors. The purpose of this manuscript is to review recent literature dealing with the descriptive epidemiology and risk factors of CCA with a special effort to compare IH- with EH-CCA.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
