Background A 71-year-old woman was referred to a surgical oncology clinic after CT raised suspicion for a bladder neoplasm. She had previously undergone right hemicolectomy and received adjuvant chemotherapy for pT3N1MX cancer of the cecum. A retroperitoneal recurrence had been deemed unsuitable for surgical resection, and had instead been treated with chemoradiation therapy. Follow-up CT raised suspicion for a possible bladder neoplasm. Investigations CT, physical examination, urinalysis, cystoscopy with biopsy, pathological analysis and immunohistochemical analysis. Diagnosis Adenocarcinoma of the cecum metastatic to the bladder. Management The patient underwent open bladder resection with total excision of the neoplasm and was administered adjuvant chemotherapy consisting of irinotecan and cetuximab. Subsequent recurrences at the same site were treated with transurethral resection, while chemotherapy was still in progress. At 7 months' follow-up, the patient remained alive, with no evidence of further recurrence.

A case of relapsing secondary bladder adenocarcinoma after right colonic cancer / Izzo, Luciano; Pietrasanta, Dario; Paolo, Izzo; Mario, Caputo; Pierfrancesco Di, Cello; Meloni, Paolo; Bolognese, Antonio. - In: NATURE CLINICAL PRACTICE UROLOGY. - ISSN 1743-4270. - STAMPA. - 5:7(2008), pp. 403-407. [10.1038/ncpuro1155]

A case of relapsing secondary bladder adenocarcinoma after right colonic cancer

IZZO, Luciano;PIETRASANTA, DARIO;Paolo Izzo;MELONI, PAOLO;BOLOGNESE, Antonio
2008

Abstract

Background A 71-year-old woman was referred to a surgical oncology clinic after CT raised suspicion for a bladder neoplasm. She had previously undergone right hemicolectomy and received adjuvant chemotherapy for pT3N1MX cancer of the cecum. A retroperitoneal recurrence had been deemed unsuitable for surgical resection, and had instead been treated with chemoradiation therapy. Follow-up CT raised suspicion for a possible bladder neoplasm. Investigations CT, physical examination, urinalysis, cystoscopy with biopsy, pathological analysis and immunohistochemical analysis. Diagnosis Adenocarcinoma of the cecum metastatic to the bladder. Management The patient underwent open bladder resection with total excision of the neoplasm and was administered adjuvant chemotherapy consisting of irinotecan and cetuximab. Subsequent recurrences at the same site were treated with transurethral resection, while chemotherapy was still in progress. At 7 months' follow-up, the patient remained alive, with no evidence of further recurrence.
bladder adenocarcinoma; bladder metastasis; colorectal cancer; immunohistochemistry; secondary bladder adenocarcinoma
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A case of relapsing secondary bladder adenocarcinoma after right colonic cancer / Izzo, Luciano; Pietrasanta, Dario; Paolo, Izzo; Mario, Caputo; Pierfrancesco Di, Cello; Meloni, Paolo; Bolognese, Antonio. - In: NATURE CLINICAL PRACTICE UROLOGY. - ISSN 1743-4270. - STAMPA. - 5:7(2008), pp. 403-407. [10.1038/ncpuro1155]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/25749
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