The GRO1 oncogene (melanoma growth-stimulating activity alpha) has been localized in region 4q21. The involvement of this chromosomal region in clonal aberrations found in primary melanoma cell cultures could have an important role in the etiology and pathogenesis of this tumor. We characterized three primary cell cultures obtained from different patients, each of which showed clonal chromosomal aberrations involving the 4q21 region.

Involvement of the 4q21 region in human malignant melanomas. Cytogenetics and immunocytochemical characterization of three primary cell cultures / Grammatico, Paola; Roccella, M; Catricalà, C; Roccella, F; Bucher, S; Mordenti, C; Amantea, A; Di Rosa, C; DEL PORTO, Giuseppe. - In: WORLD JOURNAL OF SURGERY. - ISSN 0364-2313. - STAMPA. - 19,n.3:(1995), pp. 350-351. [10.1007/BF00299156]

Involvement of the 4q21 region in human malignant melanomas. Cytogenetics and immunocytochemical characterization of three primary cell cultures.

GRAMMATICO, Paola;DEL PORTO, Giuseppe
1995

Abstract

The GRO1 oncogene (melanoma growth-stimulating activity alpha) has been localized in region 4q21. The involvement of this chromosomal region in clonal aberrations found in primary melanoma cell cultures could have an important role in the etiology and pathogenesis of this tumor. We characterized three primary cell cultures obtained from different patients, each of which showed clonal chromosomal aberrations involving the 4q21 region.
1995
human malignant melanomas; 4q21 region
01 Pubblicazione su rivista::01a Articolo in rivista
Involvement of the 4q21 region in human malignant melanomas. Cytogenetics and immunocytochemical characterization of three primary cell cultures / Grammatico, Paola; Roccella, M; Catricalà, C; Roccella, F; Bucher, S; Mordenti, C; Amantea, A; Di Rosa, C; DEL PORTO, Giuseppe. - In: WORLD JOURNAL OF SURGERY. - ISSN 0364-2313. - STAMPA. - 19,n.3:(1995), pp. 350-351. [10.1007/BF00299156]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/256860
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